A5007286327- Tracheal and airway disorders
- Voice and Speech Disorders
- Dysphagia Assessment and Management
- Head and Neck Cancer Studies
- Esophageal and GI Pathology
- Organ and Tissue Transplantation Research
- Neurological disorders and treatments
- Botulinum Toxin and Related Neurological Disorders
- Reconstructive Surgery and Microvascular Techniques
- Transplantation: Methods and Outcomes
- Airway Management and Intubation Techniques
- Cleft Lip and Palate Research
- Parkinson's Disease Mechanisms and Treatments
- Tissue Engineering and Regenerative Medicine
- Polyomavirus and related diseases
- Electrospun Nanofibers in Biomedical Applications
- Cervical Cancer and HPV Research
- Tumors and Oncological Cases
- Head and Neck Anomalies
- Head and Neck Surgical Oncology
- Ear and Head Tumors
- 3D Printing in Biomedical Research
- Respiratory and Cough-Related Research
- Trauma Management and Diagnosis
- Additive Manufacturing and 3D Printing Technologies
Mayo Clinic Hospital
2016-2025
Mayo Clinic in Florida
2016-2025
WinnMed
2016-2025
Mayo Clinic in Arizona
2016-2025
Laryngograph (United Kingdom)
2023
Triological Society
2020
St. Michael's Hospital
2018
University of Toronto
2018
American University
2018
District of Columbia Department of Health
2018
The increased incidence of skin cancers in solid organ transplant recipients (OTR) has been well established. However, our understanding the potential aggressive behavior these largely based on findings multiple different studies analyzing isolated indicators behavior. purpose this study was to determine aggressiveness nonmelanotic a large population compared with an immunocompetent control similar cancers.Immunosuppressed transplanted patients and group matched size squamous cell carcinoma...
Surgical treatment comparisons in rare diseases are difficult secondary to the geographic distribution of patients. Fortunately, emerging technologies offer promise reduce these barriers for research.To prospectively compare outcomes 3 most common surgical approaches idiopathic subglottic stenosis (iSGS), a airway disease.In this international, prospective, 3-year multicenter cohort study, 810 patients with untreated, newly diagnosed, or previously treated iSGS were enrolled after undergoing...
Objectives/Hypothesis Idiopathic subglottic stenosis (iSGS) is a rare and potentially life‐threatening disease marked by recurrent progressive airway obstruction frequently requiring repeated surgery to stabilize the airway. Unknown etiology low prevalence have limited ability characterize natural history of iSGS resulted in variability surgical management. It uncertain how this variation relates clinical outcomes. Study Design Medical record abstraction. Methods Utilizing an international,...
<h3>Objective:</h3> This study investigates salivary gland biopsies in living patients with Parkinson disease (PD). <h3>Methods:</h3> Patients PD for ≥5 years underwent outpatient transcutaneous needle core (18-gauge or 16-gauge) of 1 submandibular gland. Minor glands were removed via a small incision the lower lip. Tissue was fixed formalin and serial 6-µm paraffin sections immunohistochemically stained phosphorylated α-synuclein reviewed evidence Lewy type α-synucleinopathy (LTS)....
Assess incidence of conductive hearing loss, ear pathology, and associated communicative disorders in cleft palate patients.Retrospective chart review 101 patients all treated at a tertiary facility since birth.The median patient age was 19 years old (range 8-25) last follow-up, 35% female. Median repair 16 months 12-60). number myringotomy tubes 3 1-7). Conductive loss (CHL) greater than 20 db PTA found 25% follow-up. Severity CHL mild 75%, moderate 21%, severe 4%. Cholesteatoma identified...
ABSTRACT Introduction Finding a peripheral tissue biopsy site to diagnose early PD would be of value for clinical care, biomarker validation, and as research enrollment criteria. Whereas autopsy advanced studies suggest that the submandibular gland is an important site, there are no in PD. The aim this study was determine whether needle reveals Lewy type alpha‐synucleinopathy Methods Twenty‐five (duration < 5 years) 10 controls underwent transcutaneous core biopsies gland. Tissue stained...
A roadblock for research on adductor spasmodic dysphonia (ADSD), abductor SD (ABSD), voice tremor (VT), and muscular tension (MTD) is the lack of criteria selecting patients with these disorders.
To evaluate the safety, immunogenicity, and efficacy of INO-3107, a DNA immunotherapy designed to elicit targeted T-cell responses against human papillomavirus (HPV) types 6 11, in adult patients with recurrent respiratory papillomatosis (RRP; NCT04398433).Eligible required ≥2 surgical interventions for RRP year preceding dosing. INO-3107 was administered by intramuscular (IM) injection followed electroporation (EP) on weeks 0, 3, 6, 9. Patients underwent debulking within 14 days prior first...
We conducted a retrospective review of patients with unknown primary head and neck cancer who underwent transoral laser microsurgery (TLM)-assisted search for an occult tumor.Fifty-two at single center primaries squamous cell carcinoma (SCC) were treated surgical algorithm.The overall rate tumor identification was 75% (39 52 patients). When selecting those cases in which TLM algorithm lingual tonsillectomy utilized, the detection 86% (31 36). Tumors most commonly found (65.0%) palatine...
Objective: Analyze demographic data collected over a 25-year experience of 718 patients with spasmodic dysphonia (SD) who have been treated botulinum toxin-A (BoNT-A) and compare our previously published studies. Methods: Seven hundred eighteen SD were 6621 BoNT-A injections at Mayo Clinic Arizona between 1989 2014. All by the same physician team. Background for each patient recorded. Results: Of patients, 557 female (77.6%). Six sixty (91.8%) had adductor (AdSD), 58 (8.1%) abductor (AbSD)....
Objectives/Hypothesis The purpose of this study is to develop consensus on key points that would support the use systemic bevacizumab for treatment recurrent respiratory papillomatosis (RRP), and provide preliminary guidance surrounding modality. Study Design Delphi method‐based survey series. Methods A multidisciplinary, multi‐institutional panel physicians with experience using RRP was established. method used identify obtain characteristics associated across five domains: 1) patient...
Abstract The North American Airway Collaborative (NoAAC) previously published a 3‐year multi‐institutional prospective cohort study showing variation in treatment effectiveness between 3 primary surgical techniques for idiopathic subglottic stenosis (iSGS). In this report, we update these findings to include 5 years of data evaluating effectiveness. Patients the NoAAC were re‐enrolled 2 additional and followed using prespecified protocol. Consistent with prior data, observation 487 iSGS...
Medical advances have enabled the realization of vascularized composite allografts and to date demonstrated reasonably successful graft survival rates. Larynx Trachea Transplantation (LT) has long been contemplated as a therapeutic option for severe laryngeal trauma patients following total laryngectomy. Progress limited most likely due lack awareness an option, technical surgical expertise, transplant centers worldwide, need multidisciplinary engagement from hospital leadership,...
Objectives/Goals: Aspiration causes or aggravates lung diseases. While bedside swallow evaluations are not sensitive/specific, gold standard tests for aspiration invasive, uncomfortable, expose patients to radiation, and resource intensive. We propose the development validation of an AI model that analyzes voice noninvasively predict aspiration. Methods/Study Population: Retrospectively recorded [i] phonations from 163 unique ENT were analyzed acoustic features including jitter, shimmer,...
Cleft lip and palate deformities are one of the most common birth defects. The alveolar cleft requires bony repair to allow proper eruption dentition. purpose this study is evaluate success in clefts examine whether addition allogenic materials improves outcomes.One hundred three patients with were identified retrospectively after institutional review board approval was obtained. authors reviewed their medical records, surgical complication rate, need for revision surgery, used. data then...
To report and compare patients' experiences with acquired subglottic stenosis (AS) versus idiopathic tracheal (ISTS).A survey was made available to patients AS ISTS. Results were analyzed for inter- intragroup differences using a 2-tailed t test.The study included 160 participants (AS n = 28; ISTS 132), predominance of female (82% AS, 98% ISTS). Acid reflux the most prevalent comorbidity across groups (42%-43%). A significant difference in time diagnosis found between groups, 32% diagnosed...
Idiopathic subglottic stenosis (iSGS) is an unexplained progressive obstruction of the upper airway that occurs almost exclusively in adult, Caucasian women. The disease characterised by mucosal inflammation and localised fibrosis resulting life-threatening blockage airway. Because high recurrence rates, patients with iSGS will frequently require multiple procedures following their initial diagnosis. Both its therapies profoundly affect patients' ability to breathe, communicate swallow. A...
There is a paucity of data regarding financial trends for procedural reimbursements in otolaryngology. The purpose this study was to evaluate monetary Medicare reimbursement rates the 20 most commonly billed otolaryngology procedures from 2000 2019.Analysis physician reimbursement.The American Academy Otolaryngology-Head and Neck Surgery database queried determine performed procedures. Next, Physician Fee Schedule Look-Up Tool Centers Medicaid Services utilized assess each top Current...