A5071736735- Cancer Immunotherapy and Biomarkers
- Immunotherapy and Immune Responses
- Cancer Genomics and Diagnostics
- Global Cancer Incidence and Screening
- Ferroptosis and cancer prognosis
- Cervical Cancer and HPV Research
- Colorectal Cancer Screening and Detection
- Cancer-related Molecular Pathways
- Hepatitis B Virus Studies
- Gastrointestinal disorders and treatments
- RNA modifications and cancer
- Genital Health and Disease
- Genetic factors in colorectal cancer
- Circular RNAs in diseases
- Liver Disease Diagnosis and Treatment
- Gastric Cancer Management and Outcomes
- Economic and Financial Impacts of Cancer
- Advances in Oncology and Radiotherapy
- Prostate Cancer Diagnosis and Treatment
- HIV/AIDS drug development and treatment
- Cancer and Skin Lesions
- Head and Neck Surgical Oncology
- Thyroid Cancer Diagnosis and Treatment
- Multiple and Secondary Primary Cancers
- Folate and B Vitamins Research
University of Bamako
2012-2025
Université des Sciences, des Techniques et des Technologies de Bamako
2019-2025
Registre général des cancers de Lille et de sa région
2024
African Field Epidemiology Network
2024
Mali-Folkecenter
2018-2023
Point University
2022
Martin Luther University Halle-Wittenberg
2018
Institut National de Recherche en Santé Publique
2005-2013
Breast cancer is the leading diagnosis and second most common cause of deaths in sub-Saharan Africa (SSA). Yet, there are few population-level survival data from none on differences by stage at diagnosis. Here, we estimate breast within SSA area, country-level human development index (HDI). We obtained a random sample 2,588 incident cases, diagnosed 2008-2015 14 population-based registries 12 countries (Benin, Cote d'Ivoire, Ethiopia, Kenya, Mali, Mauritius, Mozambique, Namibia, Seychelles,...
Abstract Background: Prostate cancer is the leading in men sub-Saharan Africa (SSA) regarding incidence and mortality. Published data from a few registries SSA suggest that rates are still rising, but there little comprehensive information on time trends of prostate incidence. Methods: We analyzed registry 13,170 incident cases aged 40 years or above, 12 population-based 11 countries, with at least 10-year span comparable data. Results: observed an increase cumulative risks (CR)...
Objectives Breast cancer is the most prevalent and second leading cause of cancer-related deaths among women after cervical in much sub-Saharan Africa. This study aims to examine prevalence sociodemographic–socioeconomic factors associated with breast screening reproductive age Design A weighted population-based cross-sectional using Demographic Health Surveys (DHS) data. We used all available data on from DHS for four African countries (Burkina Faso, Ivory Coast, Kenya Namibia). was outcome...
The Cancer Survival in Africa, Asia, and South America project (SURVCAN-3) of the International Agency for Research on aims to fill gaps availability population-level cancer survival estimates from countries these regions. Here, we analysed 18 cancers using data member registries African Registry Network across 11 sub-Saharan Africa.
Objective To analyse patient and healthcare system related factors influencing the time to first visit, diagnosis treatment of breast cancer patients in sub-Saharan Africa impact on survival order advise early detection strategies. Methods A prospective hospital cohort study was conducted at only pathology department Mali, University Hospital Bamako. All female with a between January April 2016 were interviewed structured questionnaire (N = 64) gather information about symptom recognition...
<b><i>Background:</i></b> Breast cancer, the most common cancer among women worldwide, has a high mortality rate in low-income countries. In sub-Saharan Africa, breast patients are diagnosed with advanced disease. Some studies have quantified time delay to diagnosis but very few used qualitative methods understand barriers leading delay. This study analyses throughout patient's pathway from symptom recognition treatment Mali....
PURPOSE The number of patients with childhood cancer (CC) in sub-Saharan Africa is expected to rise over the coming years. According WHO Initiative for Childhood Cancer, access care crucial and must be guided by needs their families. Our study explored barriers CC treatment from a patient's perspective guide health providers. METHODS From February September 2021, we conducted multinational cross-sectional sample nine population-based registries countries. Inclusion criteria comprised...
Abstract With the reclassification of non-invasive follicular variant papillary thyroid carcinoma as “tumors” (NIFTP), challenge diagnosing lies in recognizing invasion: blood vessel invasion (BVI) or capsular (CI). We aimed to assess reproducibility BVI and CI follicular-patterned tumors using a web-platform, under conditions close possible routine surgical pathology practice. Six-hundred-fourteen pathologists reviewed 69 lesions diagnostically challenging for CI, made available three...
Introduction: Amputation is a surgical procedure that involves the removal of limb, segment or protruding part. Objective: To assess clinical, etiological, and therapeutic aspects necrotic limbs in pediatric surgery department Gabriel Touré University Hospital. Methodology: This was prospective study from January 1, 2020 to December 31, 2022, involving all children aged 0-15 years who were treated for department. Results: We collected 35 cases with hospital frequency 2.3%. The average age...
Abstract Background Pathologists face major challenges in breast cancer diagnostics sub-Saharan Africa (SSA). The problems identified as impairing the quality of pathology reports are shortcomings equipment, organization and insufficiently qualified personnel. In addition, context cancer, immunohistochemistry (IHC) needs to be available for evaluation biomarkers. study presented, we aim describe current state order highlight unmet needs. Methods We obtained information on services within...
Abstract Objectives To describe human papillomavirus (HPV) distribution in invasive cervical carcinoma (ICC) from Mali and Senegal to compare type‐specific relative contribution among sub‐Saharan African (SSA) countries. Methods A multicentric study was conducted collect paraffin‐embedded blocks of ICC. Polymerase chain reaction, DNA enzyme immunoassay line probe assay were performed for HPV detection genotyping. Data SSA (Mozambique, Nigeria Uganda) 35 other countries compared. Results One...
Abstract Background Retinoblastoma (Rb) is the most common intraocular primary malignancy in children. In industrialised countries, cure rate about 95%. We present results of a prospective study on management Rb paediatric oncology unit Gabriel Touré Teaching Hospital and African Institute Tropical Ophthalmology, from November 1, 2011 to December 31, 2015. Procedure The aims this were evaluate treatment localised Rb, ocular prosthesis after enucleation, conservative for bilateral as well...
Abstract Ovarian cancer (OC) is one of the commonest cancers women in sub‐Saharan Africa (SSA), although to date no data have been available on time trends incidence better understand disease pattern region. We estimate by histological subtype from 12 population‐based registries 11 countries: Kenya (Nairobi), Mauritius, Seychelles, Uganda (Kampala), Congo (Brazzaville), Zimbabwe (Bulawayo and Harare), Cote d'Ivoire (Abidjan), The Gambia, Mali (Bamako), Nigeria (Ibadan) South (Eastern Cape)....
Abstract The low overall survival rates of patients with breast cancer in sub-Saharan Africa (SSA) are driven by regionally differing tumor biology, advanced stages at diagnosis, and limited access to therapy. However, it is not known whether regional differences the composition microenvironment (TME) exist affect patients’ prognosis. In this international, multicentre cohort study, 1,237 formalin-fixed, paraffin-embedded samples, including samples “African Breast Cancer-Disparities Outcomes...
Background: Breast cancer (BC) is the most common in sub-Saharan Africa (SSA). However, little known about actual therapy received by women with BC and their survival outcome at population level SSA. This study aims to describe cancer-directed patients SSA, compare these results NCCN Harmonized Guidelines for SSA (NCCN Guidelines), evaluate impact on survival. Methods: Random samples of (≥40 per registry), diagnosed from 2009 through 2015, were drawn 11 urban population–based registries 10...
Abstract Background The burden of cervical cancer is disproportionately high in low-resource settings. With limited implementation human papillomavirus (HPV) vaccines on the horizon developing world, reliable data epidemiology high-risk HPV (HR-HPV) infection distinct geographic populations essential to planners vaccination programs. purpose this study was determine whether urban patterns HR-HPV occurrence can be generalized rural areas same country, using from Mali, West Africa, as an...
Information on pathways of women seeking diagnostic services due to breast- related symptoms can help highlight challenges the healthcare system in improving early diagnosis breast cancer.We retrospectively analysed entire patient pathway, from first symptom recognition via initial visit up final at pathology service Mali. Data questionnaire-based structured interviews (n = 124) were used calculate time (median 91 days) and consecutive 21 extract information type initially visited facility...
Abstract Introduction Long-term exposure to high-risk human papillomavirus (Hr-HPV) is a well-known necessary condition for development of cervical cancer. The aim this study screen Hr-HPV using vaginal self-sampling, which more effective approach improve women’s adherence and increase screening rates. Methods This pilot included total 100 Women living with HIV (WLWHIV), recruited from the Center Listening, Care, Animation, Counseling People Living in Bamako. genotyping was performed on...
To investigate the epidemiology of human papillomavirus (HPV) infection in Malian women, for whom cervical cancer is most common and second cause cancer-related mortality.Pilot study 202 women aged 15-65 to determine prevalence rate high-risk HPV among unscreened women. Information on risk factors was collected through a standardized, structured interview clinical examination. High-risk (HR) DNA detected using signal amplification methods (hybrid capture II).High-risk 12% while visual...