A5040053574- Global Cancer Incidence and Screening
- Cancer Immunotherapy and Biomarkers
- Global Health and Surgery
- Immunotherapy and Immune Responses
- Global Health Workforce Issues
- Cervical Cancer and HPV Research
- Ferroptosis and cancer prognosis
- Cancer Genomics and Diagnostics
- Genital Health and Disease
- Colorectal Cancer Screening and Detection
- Global Maternal and Child Health
- Breast Cancer Treatment Studies
- Innovations in Medical Education
- Trauma and Emergency Care Studies
- Economic and Financial Impacts of Cancer
- Cancer Risks and Factors
- BRCA gene mutations in cancer
- Female Genital Mutilation/Cutting Issues
- Urologic and reproductive health conditions
- AI in cancer detection
- Cardiac, Anesthesia and Surgical Outcomes
- Diversity and Career in Medicine
- Circular RNAs in diseases
- Breast Lesions and Carcinomas
- Prostate Cancer Diagnosis and Treatment
Makerere University
2016-2025
Future University Hakodate
2023
Clarke International University
2023
Hudson Institute
2023
John Wiley & Sons (United States)
2023
Creative Commons
2020
Mulago Hospital
2008-2020
International Hospital Kampala
2012-2017
University of Bahrain
2012-2014
BackgroundBreast cancer is the second leading cause of death from in women sub-Saharan Africa, yet there are few well characterised large-scale survival studies with complete follow-up data. We aimed to provide robust estimates this setting and apportion gaps.MethodsThe African Breast Cancer-Disparities Outcomes (ABC-DO) prospective cohort study was done at eight hospitals across five countries (Namibia, Nigeria, South Uganda, Zambia). prospectively recruited (aged ≥18 years) who attended...
Abstract Background Triple-negative breast cancer (TNBC) exhibit characteristics quite distinct from other kinds of cancer, presenting as an aggressive disease--recurring and metastasizing more often than without tumor-specific treatment options accounts for 15% all types with higher percentages in premenopausal African-American Hispanic women. The reason this phenotype is currently the focus intensive research. However, progress hampered by lack suitable TNBC cell model systems. Methods To...
In this Policy Forum, the Bellagio Essential Surgery Group, which was formed to advocate for increased access surgery in Africa, recommends four priority areas national and international agencies target order address surgical burden of disease sub-Saharan Africa.
Background There is a growing recognition that the provision of surgical services in low-income countries inadequate to need. While constrained health budgets and worker shortages have been blamed for low rates surgery, there has little empirical data on providers surgery cost Africa. This study described range care anesthesia estimated resources dedicated at district hospitals three African countries. Methods Findings We conducted retrospective cross-sectional survey from eight Mozambique,...
In the first of two papers investigating surgical provision in eight district hospitals Saharan African countries, Margaret Kruk and colleagues find low levels care suggesting unmet need for services.
The objective was to investigate survival of breast cancer patients at Mulago Hospital. A retrospective study the medical records 297 referred combined clinic housed in radiotherapy department between 1996 and 2000 done. female/male ratio 24 : 1. age range 22–85 years, with a median 45 years peak group 30–39 years. Twenty-three percent had early disease (stages 0–IIb) 26% metastatic disease. Poorly differentiated most common pathological grade (58%) followed by moderately (33%)...
Improving breast cancer survival in sub-Saharan Africa (SSA) is urgently needed, requiring early diagnosis and improved access to treatment. However, data on the types of barriers receiving therapy this region are limited have not been compared between different SSA countries treatment settings. In health care settings across Uganda, Nigeria Namibian sites prospective African Breast Cancer - Disparities Outcomes cohort study, we assessed percentage newly diagnosed patients who received...
Despite women being disproportionally affected by cancer deaths at young ages, there are no global estimates of the resulting maternal orphans, who experience health and education disadvantages throughout their lives. We estimated number children became orphans in 2020 due to mother dying from that year, for 185 countries worldwide cause cancer-related death. Female deaths-by country, type age (derived GLOBOCAN estimates)-were multiplied each woman's under 18 years time her death (fertility...
Breast cancer (BC) survival rates in sub-Saharan Africa (SSA) are low part due to advanced stage at diagnosis. As one component of a study the entire journey SSA women with BC, we aimed identify shared and setting-specific drivers BC. Women newly diagnosed multicountry African Cancer-Disparities Outcomes (ABC-DO) completed baseline interview their information was extracted from medical records. Ordinal logistic regression used estimate odds ratios (OR) 95% confidence intervals (CI) for (I,...
Cancer of the breast is a major health burden and most common cancer among women worldwide. Though its incidence fourfold greater in high-income countries, sharp contrast, mortality rates are greatest low-income countries. Early detection linked to appropriate treatment effective strategy improve survival. The purpose this study therefore was establish survival experiences with at Ugandan hospital.
Little is known about the prevalence of pediatric surgical conditions in low- and middle-income countries. Many children never seek medical care, thus true Uganda unknown. The objective this study was to determine Uganda.Using Surgeons OverSeas Assessment Surgical Need (SOSAS) survey, we enumerated 4248 individuals 2315 households 105 randomly selected clusters throughout Uganda. Children aged 0-18 were included if from household; for those who could not answer themselves, parents served as...
Community transmission of COVID-19 is already being reported in Africa.1 Most countries on the continent will have +10,000 confirmed cases within month.2 The population, while generally younger than Europe and North America, has much higher rates poverty, malnutrition, HIV, TB, which could shift demographics lethality. For surgeons, obstetricians, anesthesiologists, major challenge be maintaining provision emergency essential surgery obstetric care preserving precious resources, minimizing...
In low income countries, many patients with breast cancer present advanced disease which is majorly attributed to late presentation and this associated poor survival rates. The aim of study was determine the magnitude patient delay factors that influence, in seeking health care female patients.A cross-sectional done between January April 2014 at a tertiary unit. Female above age 18 years were interviewed. Ethical approval obtained.In total 162 recruited, mean months 22.6 (SD = 26.4), median...
Introduction Sub-Saharan African (SSA) women with breast cancer (BC) have low survival rates from this potentially treatable disease. An understanding of context-specific societal, health-systems and woman-level barriers to BC early detection, diagnosis treatment are needed. Methods The Breast Cancer—Disparities in Outcomes (ABC-DO) is a prospective hospital-based study overall survival, impact on quality life (QOL) delays along the journey SSA. ABC-DO currently recruiting Namibia, Nigeria,...
Open AccessUnravelling bladder cancer in Uganda: insights from the discrepancies TP53 assessment between immunohistochemistry and whole exome sequencing B Ssekitooleko, H Nalwoga, S Kalungi, N Kiwanuka, M Galukande, D Namuguzi, I Kajja, Ssuna, F Asiimwe, J Kuteesa, JB Masaba Muwonge Ssekitooleko12 https://orcid.org/0000-0002-3561-055X , Nalwoga1 https://orcid.org/0000-0002-2965-9445 Kalungi3 https://orcid.org/0009-0003-4877-3184 Kiwanuka1 https://orcid.org/0000-0003-2471-9290 Galukande1...
Anecdotal evidence shows that unprofessional conduct is becoming a common occurrence amongst health workers in Uganda. The development of appropriate professional values, attitudes and behaviors continuum starts when student joins training institution as such professionals need to be exposed the essence professionalism. We sought explore undergraduate professions students' perceptions experiences learning professionalism preliminary step addressing problem Eight focus group discussions were...
The shortage and mal-distribution of surgical specialists in sub-Saharan African countries is born out individuals choosing a career, limited training capacity, inadequate remuneration, reluctance on the part professionals to work rural remote areas, among other reasons. This study set assess views clinicians managers use task shifting as an effective way alleviating shortages skilled personnel at facility level. 37 in-depth interviews with key informants 24 focus group discussions were held...
Good sanitation and clean water are basic human rights yet they remain elusive to many rural communities in Sub-Saharan Africa (SSA). We carried out a cross sectional study examine the impact of four-year intervention aimed at improving access reducing waterborne disease, especially diarrhea children under five years old. The was April May 2015 Busangi, Chela Ntobo wards Kahama District Tanzania. interventions included education campaigns improved supply, sanitation. percentage households...
Mammography, the gold standard for breast cancer screening misses some cancers, especially in women with dense breasts. Breast ultrasonography as a supplementary imaging tool further evaluation of symptomatic mammographically breasts may improve detection mass lesions otherwise missed at mammography. The purpose this study was to determine incremental rate using US scanning resource poor environment. A cross sectional descriptive study. Women referred mammography underwent bilateral...