A5018765418- Cancer Immunotherapy and Biomarkers
- Immunotherapy and Immune Responses
- Global Cancer Incidence and Screening
- Ferroptosis and cancer prognosis
- Cancer Genomics and Diagnostics
- Tattoo and Body Piercing Complications
- Body Image and Dysmorphia Studies
- Child Development and Digital Technology
- Impact of Technology on Adolescents
- Colorectal Cancer Screening and Detection
- Cervical Cancer and HPV Research
- Dermatologic Treatments and Research
- Electromagnetic Fields and Biological Effects
- Economic and Financial Impacts of Cancer
- Circular RNAs in diseases
- Cancer Risks and Factors
- Social Media and Politics
- Breast Cancer Treatment Studies
- Energy Harvesting in Wireless Networks
- Family Support in Illness
- Viral-associated cancers and disorders
- Cancer survivorship and care
- Cancer Diagnosis and Treatment
- Sexuality, Behavior, and Technology
- Identity, Memory, and Therapy
Centre International de Recherche sur le Cancer
2018-2025
Hudson Institute
2023
John Wiley & Sons (United States)
2023
World Health Organization - Pakistan
2019-2022
Swiss Tropical and Public Health Institute
2015-2021
World Health Organization
2021
University of Basel
2017-2020
Swiss School of Public Health
2018
BackgroundBreast cancer is the second leading cause of death from in women sub-Saharan Africa, yet there are few well characterised large-scale survival studies with complete follow-up data. We aimed to provide robust estimates this setting and apportion gaps.MethodsThe African Breast Cancer-Disparities Outcomes (ABC-DO) prospective cohort study was done at eight hospitals across five countries (Namibia, Nigeria, South Uganda, Zambia). prospectively recruited (aged ≥18 years) who attended...
Nocturnal media use has been linked to adolescents' sleeping problems in cross-sectional studies which do not address reverse causality. To prospectively assess the new occurrence of sleep or health symptoms relation electronic and nocturnal mobile phone use, we used data from longitudinal Swiss HERMES (Health Effects Related Mobile usE adolescentS) cohort on 843 children 7th 9th grade. Logistic regression models were fitted adjusted for relevant confounders. Adolescents reporting at...
Improving breast cancer survival in sub-Saharan Africa (SSA) is urgently needed, requiring early diagnosis and improved access to treatment. However, data on the types of barriers receiving therapy this region are limited have not been compared between different SSA countries treatment settings. In health care settings across Uganda, Nigeria Namibian sites prospective African Breast Cancer - Disparities Outcomes cohort study, we assessed percentage newly diagnosed patients who received...
Despite safety concerns regarding the toxicity of tattoo ink, no studies have reported consequences tattooing on immune response. In this work, we characterized transport and accumulation different inks in lymphatic system using a murine model. Upon quick drainage, observed that macrophages mainly capture ink lymph node (LN). An initial inflammatory reaction at local systemic levels follows capture. Notably, process is maintained over time as clear signs inflammation draining LN two months...
About one-fifth of people in industrialised countries are tattooed, potentially putting them at risk exposure to possible carcinogenic or otherwise harmful substances. This study aims determine the soluble tattoo ink ingredients and their excretion within 24 h after tattooing. In this clinical study, subjects were tattooed with black red which 3 tracer substances, potassium iodide, 4-aminobenzoic acid (PABA) 2-phenoxyethanol (PEtOH), had been added mimic known substances found inks. Tracers...
Background: The potential impact of microwave radiofrequency electromagnetic fields (RF-EMF) emitted by wireless communication devices on neurocognitive functions adolescents is controversial. In a previous analysis, we found changes in figural memory scores associated with higher cumulative RF-EMF brain dose adolescents. Objective: We aimed to follow-up our results using new study population, estimation, and approach controlling for confounding from media usage itself. Methods: each...
Most breast cancer patients in sub-Saharan Africa are diagnosed at advanced stages after prolonged symptomatic periods. In the multicountry African Breast Cancer-Disparities Outcomes cohort, we dissected diagnostic journey to inform downstaging interventions. At hospital presentation for cancer, women recalled their journey, including dates of first noticing symptoms and health-care provider (HCP) visits. Negative binomial regression models were used identify correlates length journey. Among...
Abstract We examined the geospatial dimension of delays to diagnosis breast cancer in a prospective study 1541 women newly diagnosed African Breast Cancer—Disparities Outcomes (ABC‐DO) Study. Women were recruited at treatment facilities Namibia, Nigeria, Uganda and Zambia. The baseline interview included information used generate features: urban/rural residence, travel mode facility straight‐line distances from home first‐care provider diagnostic/treatment facility, categorized into...
Low breast cancer survival in sub-Saharan Africa's young population increases the likelihood that deaths result maternal orphans, ie, children (<18 years) losing their mother.
Abstract The low overall survival rates of patients with breast cancer in sub-Saharan Africa (SSA) are driven by regionally differing tumor biology, advanced stages at diagnosis, and limited access to therapy. However, it is not known whether regional differences the composition microenvironment (TME) exist affect patients’ prognosis. In this international, multicentre cohort study, 1,237 formalin-fixed, paraffin-embedded samples, including samples “African Breast Cancer-Disparities Outcomes...
There is an urgent need to improve breast cancer survival in sub-Saharan Africa. Geospatial barriers delay diagnosis and treatment, but their effect on these settings not well understood. We examined geospatial disparities 4-year the African Breast Cancer-Disparities Outcomes cohort. In this prospective cohort study, women (aged ≥18 years) newly diagnosed with were recruited from eight hospitals Namibia, Nigeria, South Africa, Uganda, Zambia. They reported sociodemographic information...
Accurate survival estimates are needed for guiding cancer control efforts in sub-Saharan Africa, but previous studies have been hampered by unknown biases due to excessive loss follow-up (LTFU). In the African Breast Cancer-Disparities Outcomes Study, a prospective breast cohort study, we implemented active mobile health follow-up, telephoning each woman or her next-of-kin (NOK) trimonthly on phone update information vital status. Dates of every contact with women/NOK were analyzed from...
Tattooing, whose popularity is growing worldwide, an invasive body art that involves the injection of chemical mixtures, tattoo ink, into upper layer dermis. Although these inks may contain environmental toxins, including known human carcinogens, their long-term health effects are poorly studied. To conduct urgently required epidemiological studies on tattoos and effects, a validated method for assessing complex exposure needed.