- Tattoo and Body Piercing Complications
- Body Image and Dysmorphia Studies
- Dermatologic Treatments and Research
- Contact Dermatitis and Allergies
- Sexuality, Behavior, and Technology
- Visual Culture and Art Theory
- Skin Protection and Aging
- Mycotoxins in Agriculture and Food
- Laser Applications in Dentistry and Medicine
- Bee Products Chemical Analysis
- Plant Pathogens and Fungal Diseases
- Cultural Heritage Materials Analysis
- Photopolymerization techniques and applications
- Forensic Toxicology and Drug Analysis
- Plant-Microbe Interactions and Immunity
- Martial Arts: Techniques, Psychology, and Education
- Ocular Surface and Contact Lens
- Dyeing and Modifying Textile Fibers
- melanin and skin pigmentation
- Advancements in Transdermal Drug Delivery
Federal Institute for Risk Assessment
2016-2025
University of Amsterdam
2013
Abstract Background The plant-pathogenic fungus Fusarium oxysporum f.sp .lycopersici ( Fol ) has accessory, lineage-specific (LS) chromosomes that can be transferred horizontally between strains. A single LS chromosome in the Fol4287 reference strain harbors all known effector genes. Transfer of this pathogenicity confers virulence to a previously non-pathogenic recipient strain. We hypothesize expression and evolution genes is influenced by their genomic context. Results To gain better...
The increasing prevalence of tattoos provoked safety concerns with respect to particle distribution and effects inside the human body. We used skin lymphatic tissues from corpses address local biokinetics by means synchrotron X-ray fluorescence (XRF) techniques at both micro (μ) nano (ν) scale. Additional advanced mass spectrometry-based methodology enabled demonstrate simultaneous transport organic pigments, heavy metals titanium dioxide regional lymph nodes. Among these compounds, pigments...
About one-fifth of people in industrialised countries are tattooed, potentially putting them at risk exposure to possible carcinogenic or otherwise harmful substances. This study aims determine the soluble tattoo ink ingredients and their excretion within 24 h after tattooing. In this clinical study, subjects were tattooed with black red which 3 tracer substances, potassium iodide, 4-aminobenzoic acid (PABA) 2-phenoxyethanol (PEtOH), had been added mimic known substances found inks. Tracers...
Abstract Background Red tattoos are prone to allergic reactions. The identity of the allergen(s) is mostly unknown. Objectives Chemical analysis human skin biopsies from chronic reactions in red identify culprit pigment(s) and metals. Material methods One hundred four dermatome were analyzed by matrix‐assisted laser desorption/ionization tandem mass spectrometry (MALDI‐MS/MS) for identification commonly used organic pigments. Metal concentrations assessed inductively coupled plasma (ICP)‐MS...
Allergic reactions to tattoos are amongst the most common side effects occurring with this permanent deposition of pigments into dermal skin layer. The characterization such and their distribution has been investigated in recent decades. health impact tattoo equipment on extensive number people inked focus neither research nor medical diagnostics. Although needles contain high amounts sensitizing elements like nickel (Ni) chromium (Cr), influence metal never investigated. Here, we report...
Abstract Since laser treatment of tattoos is the favored method for removing no longer wanted permanent skin paintings, analytical, biokinetics and toxicological data on fragmentation pattern commonly used pigments are urgently required health safety reasons. Applying dynamic headspace—gas chromatography with mass spectrometric detection (DHS—GC/MS) comprehensive two-dimensional gas coupled to time-of-flight spectrometry (GCxGC—ToF-MS), we identified 1,2-benzene dicarbonitrile, benzonitrile,...
The implementation of regulation for tattoo ink ingredients across Europe has generated the need analytical methods suitable to identify prohibited compounds. Common challenges this subject are poor solubility and lack volatility most pigments polymers applied in inks. Here, we present pyrolysis coupled online gas chromatography electron impact ionization mass spectrometry (py-GC/MS) as quick reliable tool pigment identification using both purified formulations. Some 36 organic frequently...
Summary Background Allergic reactions to tattoos are not uncommon. However, identification of the culprit allergen(s) remains challenging. Objectives We present a patient with papulo‐nodular infiltration 20‐year‐old associated systemic symptoms that disappeared within week after surgical removal metal osteosynthesis implants from his spine. aimed explore causal relationship between and patient's clinical presentation. Methods Metal skin biopsy reactive tattoo were analysed for elemental...
<b><i>Introduction:</i></b> Pigments of tattoo inks may over time migrate to other parts the body. Inks kinetics are still poorly understood and little studied. The aim this first study was investigate pigment in tattooed porcine skin, which is closer human skin than mouse studied past. <b><i>Methods:</i></b> Three animals were on inner thigh one animal served as untreated control. Skin biopsies taken days 7, 14, 28 after tattooing. Animals...
Abstract Reports of tattoo-associated risks boosted the interest in tattoo pigment toxicity over last decades. Nonetheless, influence pigments on skin homeostasis remains largely unknown. In vitro systems are not available to investigate interactions between and skin. Here, we established TatS, a reconstructed human full-thickness model with incorporated into dermis. We mixed most frequently used carbon black (0.02 mg/ml) titanium dioxide (TiO 2 , 0.4 as well organic diazo compound Pigment...
Tattooing, whose popularity is growing worldwide, an invasive body art that involves the injection of chemical mixtures, tattoo ink, into upper layer dermis. Although these inks may contain environmental toxins, including known human carcinogens, their long-term health effects are poorly studied. To conduct urgently required epidemiological studies on tattoos and effects, a validated method for assessing complex exposure needed.
Highly specific identification of water-insoluble organic pigments is facilitated by automated matrix-assisted laser desorption/ionization tandem mass spectrometry and data evaluation.
Tattoos have been gaining popularity in recent years, leading to a growing interest researching tattoo inks and the tattooing process itself. Since exposure soluble ink ingredients has not yet investigated, we here present method validation for short-term biokinetics study on ingredients. The three tracers 4-aminobenzoic acid (PABA), 2-phenoxyethanol (PEtOH) iodine will be added commercially available inks, which subsequently used healthy participants. Following process, blood urine sampled...
Just as the number of tattooed people has increased in recent years, so adverse reactions skin. Tattoo colourants contain numerous, partly unidentified substances, which have potential to provoke skin like allergies or granulomatous reactions. Identification triggering substances is often difficult even impossible.Ten patients with typical were enrolled study. Skin punch biopsies taken and paraffin-embedded specimens analysed by standard haematoxylin eosin anti-CD3 stainings. provided...