Tewodros Yalew
A5061569159- Cancer Immunotherapy and Biomarkers
- Immunotherapy and Immune Responses
- Ferroptosis and cancer prognosis
- Cancer Genomics and Diagnostics
- Global Cancer Incidence and Screening
- Circular RNAs in diseases
- Autopsy Techniques and Outcomes
- African history and culture analysis
- Cancer Cells and Metastasis
- Liver Disease Diagnosis and Treatment
- Human Rights and Development
- Parasitic Diseases Research and Treatment
- Historical and Contemporary Political Dynamics
Addis Ababa University
2021-2024
Tikur Anbessa Hospital
2023
Abstract The low overall survival rates of patients with breast cancer in sub-Saharan Africa (SSA) are driven by regionally differing tumor biology, advanced stages at diagnosis, and limited access to therapy. However, it is not known whether regional differences the composition microenvironment (TME) exist affect patients’ prognosis. In this international, multicentre cohort study, 1,237 formalin-fixed, paraffin-embedded samples, including samples “African Breast Cancer-Disparities Outcomes...
<p>Figure S1: Consort diagram of the analyzed samples</p>
<p>Figure S1: Consort diagram of the analyzed samples</p>
<p>Figure S2: TILs in SSA</p>
<p>Figure S3: Immune cell subpopulations in SSA</p>
<p>Figure S2: TILs in SSA</p>
<p>Figure S4:PD-L1 expression and cytotoxicity</p>
<p>Figure S3: Immune cell subpopulations in SSA</p>
<p>Figure S5: MHC I expression in SSA</p>
<p>Figure S4:PD-L1 expression and cytotoxicity</p>
<p>Figure S5: MHC I expression in SSA</p>
<p>Figure S6: Multivariate Cox regression analysis of patient's survival.</p>
<p>Figure S6: Multivariate Cox regression analysis of patient's survival.</p>
Diagnostic autopsy has been in use for long to determine the cause of death. Since recently however 'Minimally Invasive Tissue Sampling' (MITS) is introduced definitive neonatal This study describes locally established facilitators introduce MITS procedures death Ethiopia. Exploratory was conducted Butajira community where twenty-two key informants representing opinion leaders' health care workers, five depth interviews with parents who lost neonates and eight FGDs members were completed...
Background: With a neonatal mortality rate of 33 per 1000 livebirths in 2021, Ethiopia is working hard to attain the SDG target 12 deaths 1,000 by 2030. A better understanding major causes needed effectively design and implement interventions achieve this goal. Minimally Invasive Tissue Sampling (MITS), an alternative conventional autopsy, requires fewer resources through task-shifting sample collection from pathologists nurses, has potential support expansion pathology-based post-mortem...
Background: With a neonatal mortality rate of 33 per 1000 livebirths in 2021, Ethiopia is working hard to attain the SDG target 12 deaths 1,000 by 2030. A better understanding major causes needed effectively design and implement interventions achieve this goal. Minimally Invasive Tissue Sampling (MITS), an alternative conventional autopsy, requires fewer resources through task-shifting sample collection from pathologists nurses, has potential support expansion pathology-based post-mortem...
<p>Figure S6: Multivariate Cox regression analysis of patient's survival.</p>
<p>Figure S3: Immune cell subpopulations in SSA</p>