Login

Tariku W. Kenea

ORCID: 0009-0003-0502-5880
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
A5028677865
Research Areas
  • Cancer Immunotherapy and Biomarkers
  • Immunotherapy and Immune Responses
  • Ferroptosis and cancer prognosis
  • Cancer Genomics and Diagnostics
  • Global Cancer Incidence and Screening
  • Circular RNAs in diseases
  • Breast Cancer Treatment Studies
  • Liver Disease Diagnosis and Treatment
  • Cancer Cells and Metastasis
  • BRCA gene mutations in cancer
  • AI in cancer detection
 Regional Variation in the Tumor Microenvironment, Immune Escape and Prognostic Factors in Breast Cancer in Sub-Saharan Africa
OPENALEX - Publications 
Marcus Bauer Martina Vetter Kathrin Stückrath Meron Yohannes Zelalem Desalegn and 27 more Tewodros Yalew Yonas Bekuretsion Tariku W. Kenea Maureen Joffe Eunice J. van den Berg Julien I. Nikulu Bakarou Kamaté Shyam S. Manraj Olufemi J. Ogunbiyi Ima-Obong Ekanem Festus Igbinoba Mohenou Diomande Clement Adebamowo Charles P. Dzamalala Angelica A. Anele Annelle Zietsman Moses Galukande Milena Foerster Isabel dos‐Santos‐Silva Biying Liu Pablo Santos Ahmedin Jemal Tamrat Abebe Claudia Wickenhauser Barbara Seliger Valerie McCormack Eva Johanna Kantelhardt

Abstract The low overall survival rates of patients with breast cancer in sub-Saharan Africa (SSA) are driven by regionally differing tumor biology, advanced stages at diagnosis, and limited access to therapy. However, it is not known whether regional differences the composition microenvironment (TME) exist affect patients’ prognosis. In this international, multicentre cohort study, 1,237 formalin-fixed, paraffin-embedded samples, including samples “African Breast Cancer-Disparities Outcomes...

10.1158/2326-6066.cir-22-0795 article EN Cancer Immunology Research 2023-04-14
 PAM50 breast cancer subtypes and survival of patients in rural Ethiopia without adjuvant treatment: a prospective observational study
OPENALEX - Publications 
Judith Katharina Ballé Martina Vetter Tariku W. Kenea Pia Eber-Schulz Christian Reibold and 8 more Hannes-Viktor Ziegenhorn Kathrin Stückrath Claudia Wickenhauser Adamu Addissie Pablo Santos Eva Johanna Kantelhardt Sefonias Getachew Marcus Bauer

10.1186/s12885-024-12867-6 article EN cc-by BMC Cancer 2024-09-10
 Biologie des Mammakarzinoms in Äthiopien
OPENALEX - Publications 
Martina Vetter Judith Katharina Ballé Marcus Bauer S. Kaudhold Pablo Santos and 2 more Tariku W. Kenea E Kantelhardt

Hintergrund und Fragestellung Das Mammakarzinom ist in den meisten afrikanischen Ländern die Krebserkrankung mit der höchsten Inzidenz einer deutlich höheren Sterberate im Vergleich zu westlichen (teilweise> 50% versus 10% nach fünf Jahren). Genexpressionsprofile ermöglichen Kategorisierung vom klinisch bzw. therapierelevante intrinsische Subtypen (IS). Ziel Studie war, das Überleben von äthiopischen Patientinnen entsprechend IS analysieren.

10.1055/s-0044-1787257 article DE Geburtshilfe und Frauenheilkunde 2024-06-01
 Supplementary Figure 1 from Regional variation in the tumor microenvironment, immune escape and prognostic factors in breast cancer in sub-Saharan Africa
OPENALEX - Publications 
Marcus Bauer Martina Vetter Kathrin Stückrath Meron Yohannes Zelalem Desalegn and 27 more Tewodros Yalew Yonas Bekuretsion Tariku W. Kenea Maureen Joffe Eunice J. van den Berg Julien I. Nikulu Bakarou Kamaté Shyam S. Manraj Olufemi J. Ogunbiyi Ima-Obong Ekanem Festus Igbinoba Mohenou Diomande Clement Adebamowo Charles P. Dzamalala Angelica A. Anele Annelle Zietsman Moses Galukande Milena Foerster Isabel dos‐Santos‐Silva Biying Liu Pablo Santos Ahmedin Jemal Tamrat Abebe Claudia Wickenhauser Barbara Seliger Valerie McCormack Eva Johanna Kantelhardt

<p>Figure S1: Consort diagram of the analyzed samples</p>

10.1158/2326-6066.27026444.v1 preprint EN 2024-09-16
 Supplementary Figure 1 from Regional variation in the tumor microenvironment, immune escape and prognostic factors in breast cancer in sub-Saharan Africa
OPENALEX - Publications 
Marcus Bauer Martina Vetter Kathrin Stückrath Meron Yohannes Zelalem Desalegn and 27 more Tewodros Yalew Yonas Bekuretsion Tariku W. Kenea Maureen Joffe Eunice J. van den Berg Julien I. Nikulu Bakarou Kamaté Shyam S. Manraj Olufemi J. Ogunbiyi Ima-Obong Ekanem Festus Igbinoba Mohenou Diomande Clement Adebamowo Charles P. Dzamalala Angelica A. Anele Annelle Zietsman Moses Galukande Milena Foerster Isabel dos‐Santos‐Silva Biying Liu Pablo Santos Ahmedin Jemal Tamrat Abebe Claudia Wickenhauser Barbara Seliger Valerie McCormack Eva Johanna Kantelhardt

<p>Figure S1: Consort diagram of the analyzed samples</p>

10.1158/2326-6066.27026444 preprint EN 2024-09-16
 Supplementary Figure 2 from Regional variation in the tumor microenvironment, immune escape and prognostic factors in breast cancer in sub-Saharan Africa
OPENALEX - Publications 
Marcus Bauer Martina Vetter Kathrin Stückrath Meron Yohannes Zelalem Desalegn and 27 more Tewodros Yalew Yonas Bekuretsion Tariku W. Kenea Maureen Joffe Eunice J. van den Berg Julien I. Nikulu Bakarou Kamaté Shyam S. Manraj Olufemi J. Ogunbiyi Ima-Obong Ekanem Festus Igbinoba Mohenou Diomande Clement Adebamowo Charles P. Dzamalala Angelica A. Anele Annelle Zietsman Moses Galukande Milena Foerster Isabel dos‐Santos‐Silva Biying Liu Pablo Santos Ahmedin Jemal Tamrat Abebe Claudia Wickenhauser Barbara Seliger Valerie McCormack Eva Johanna Kantelhardt

<p>Figure S2: TILs in SSA</p>

10.1158/2326-6066.27026441 preprint NL 2024-09-16
 Supplementary Figure 3 from Regional variation in the tumor microenvironment, immune escape and prognostic factors in breast cancer in sub-Saharan Africa
OPENALEX - Publications 
Marcus Bauer Martina Vetter Kathrin Stückrath Meron Yohannes Zelalem Desalegn and 27 more Tewodros Yalew Yonas Bekuretsion Tariku W. Kenea Maureen Joffe Eunice J. van den Berg Julien I. Nikulu Bakarou Kamaté Shyam S. Manraj Olufemi J. Ogunbiyi Ima-Obong Ekanem Festus Igbinoba Mohenou Diomande Clement Adebamowo Charles P. Dzamalala Angelica A. Anele Annelle Zietsman Moses Galukande Milena Foerster Isabel dos‐Santos‐Silva Biying Liu Pablo Santos Ahmedin Jemal Tamrat Abebe Claudia Wickenhauser Barbara Seliger Valerie McCormack Eva Johanna Kantelhardt

<p>Figure S3: Immune cell subpopulations in SSA</p>

10.1158/2326-6066.27026438 preprint FR 2024-09-16
 Supplementary Figure 2 from Regional variation in the tumor microenvironment, immune escape and prognostic factors in breast cancer in sub-Saharan Africa
OPENALEX - Publications 
Marcus Bauer Martina Vetter Kathrin Stückrath Meron Yohannes Zelalem Desalegn and 27 more Tewodros Yalew Yonas Bekuretsion Tariku W. Kenea Maureen Joffe Eunice J. van den Berg Julien I. Nikulu Bakarou Kamaté Shyam S. Manraj Olufemi J. Ogunbiyi Ima-Obong Ekanem Festus Igbinoba Mohenou Diomande Clement Adebamowo Charles P. Dzamalala Angelica A. Anele Annelle Zietsman Moses Galukande Milena Foerster Isabel dos‐Santos‐Silva Biying Liu Pablo Santos Ahmedin Jemal Tamrat Abebe Claudia Wickenhauser Barbara Seliger Valerie McCormack Eva Johanna Kantelhardt

<p>Figure S2: TILs in SSA</p>

10.1158/2326-6066.27026441.v1 preprint NL 2024-09-16
 Supplementary Figure 4 from Regional variation in the tumor microenvironment, immune escape and prognostic factors in breast cancer in sub-Saharan Africa
OPENALEX - Publications 
Marcus Bauer Martina Vetter Kathrin Stückrath Meron Yohannes Zelalem Desalegn and 27 more Tewodros Yalew Yonas Bekuretsion Tariku W. Kenea Maureen Joffe Eunice J. van den Berg Julien I. Nikulu Bakarou Kamaté Shyam S. Manraj Olufemi J. Ogunbiyi Ima-Obong Ekanem Festus Igbinoba Mohenou Diomande Clement Adebamowo Charles P. Dzamalala Angelica A. Anele Annelle Zietsman Moses Galukande Milena Foerster Isabel dos‐Santos‐Silva Biying Liu Pablo Santos Ahmedin Jemal Tamrat Abebe Claudia Wickenhauser Barbara Seliger Valerie McCormack Eva Johanna Kantelhardt

<p>Figure S4:PD-L1 expression and cytotoxicity</p>

10.1158/2326-6066.27026435 preprint EN 2024-09-16
 Supplementary Figure 3 from Regional variation in the tumor microenvironment, immune escape and prognostic factors in breast cancer in sub-Saharan Africa
OPENALEX - Publications 
Marcus Bauer Martina Vetter Kathrin Stückrath Meron Yohannes Zelalem Desalegn and 27 more Tewodros Yalew Yonas Bekuretsion Tariku W. Kenea Maureen Joffe Eunice J. van den Berg Julien I. Nikulu Bakarou Kamaté Shyam S. Manraj Olufemi J. Ogunbiyi Ima-Obong Ekanem Festus Igbinoba Mohenou Diomande Clement Adebamowo Charles P. Dzamalala Angelica A. Anele Annelle Zietsman Moses Galukande Milena Foerster Isabel dos‐Santos‐Silva Biying Liu Pablo Santos Ahmedin Jemal Tamrat Abebe Claudia Wickenhauser Barbara Seliger Valerie McCormack Eva Johanna Kantelhardt

<p>Figure S3: Immune cell subpopulations in SSA</p>

10.1158/2326-6066.27026438.v1 preprint FR 2024-09-16
 Supplementary Figure 5 from Regional variation in the tumor microenvironment, immune escape and prognostic factors in breast cancer in sub-Saharan Africa
OPENALEX - Publications 
Marcus Bauer Martina Vetter Kathrin Stückrath Meron Yohannes Zelalem Desalegn and 27 more Tewodros Yalew Yonas Bekuretsion Tariku W. Kenea Maureen Joffe Eunice J. van den Berg Julien I. Nikulu Bakarou Kamaté Shyam S. Manraj Olufemi J. Ogunbiyi Ima-Obong Ekanem Festus Igbinoba Mohenou Diomande Clement Adebamowo Charles P. Dzamalala Angelica A. Anele Annelle Zietsman Moses Galukande Milena Foerster Isabel dos‐Santos‐Silva Biying Liu Pablo Santos Ahmedin Jemal Tamrat Abebe Claudia Wickenhauser Barbara Seliger Valerie McCormack Eva Johanna Kantelhardt

<p>Figure S5: MHC I expression in SSA</p>

10.1158/2326-6066.27026432 preprint EN 2024-09-16
 Supplementary Figure 4 from Regional variation in the tumor microenvironment, immune escape and prognostic factors in breast cancer in sub-Saharan Africa
OPENALEX - Publications 
Marcus Bauer Martina Vetter Kathrin Stückrath Meron Yohannes Zelalem Desalegn and 27 more Tewodros Yalew Yonas Bekuretsion Tariku W. Kenea Maureen Joffe Eunice J. van den Berg Julien I. Nikulu Bakarou Kamaté Shyam S. Manraj Olufemi J. Ogunbiyi Ima-Obong Ekanem Festus Igbinoba Mohenou Diomande Clement Adebamowo Charles P. Dzamalala Angelica A. Anele Annelle Zietsman Moses Galukande Milena Foerster Isabel dos‐Santos‐Silva Biying Liu Pablo Santos Ahmedin Jemal Tamrat Abebe Claudia Wickenhauser Barbara Seliger Valerie McCormack Eva Johanna Kantelhardt

<p>Figure S4:PD-L1 expression and cytotoxicity</p>

10.1158/2326-6066.27026435.v1 preprint EN 2024-09-16
 Supplementary Figure 5 from Regional variation in the tumor microenvironment, immune escape and prognostic factors in breast cancer in sub-Saharan Africa
OPENALEX - Publications 
Marcus Bauer Martina Vetter Kathrin Stückrath Meron Yohannes Zelalem Desalegn and 27 more Tewodros Yalew Yonas Bekuretsion Tariku W. Kenea Maureen Joffe Eunice J. van den Berg Julien I. Nikulu Bakarou Kamaté Shyam S. Manraj Olufemi J. Ogunbiyi Ima-Obong Ekanem Festus Igbinoba Mohenou Diomande Clement Adebamowo Charles P. Dzamalala Angelica A. Anele Annelle Zietsman Moses Galukande Milena Foerster Isabel dos‐Santos‐Silva Biying Liu Pablo Santos Ahmedin Jemal Tamrat Abebe Claudia Wickenhauser Barbara Seliger Valerie McCormack Eva Johanna Kantelhardt

<p>Figure S5: MHC I expression in SSA</p>

10.1158/2326-6066.27026432.v1 preprint EN 2024-09-16
 Supplementary Figure 6 from Regional variation in the tumor microenvironment, immune escape and prognostic factors in breast cancer in sub-Saharan Africa
OPENALEX - Publications 
Marcus Bauer Martina Vetter Kathrin Stückrath Meron Yohannes Zelalem Desalegn and 27 more Tewodros Yalew Yonas Bekuretsion Tariku W. Kenea Maureen Joffe Eunice J. van den Berg Julien I. Nikulu Bakarou Kamaté Shyam S. Manraj Olufemi J. Ogunbiyi Ima-Obong Ekanem Festus Igbinoba Mohenou Diomande Clement Adebamowo Charles P. Dzamalala Angelica A. Anele Annelle Zietsman Moses Galukande Milena Foerster Isabel dos‐Santos‐Silva Biying Liu Pablo Santos Ahmedin Jemal Tamrat Abebe Claudia Wickenhauser Barbara Seliger Valerie McCormack Eva Johanna Kantelhardt

<p>Figure S6: Multivariate Cox regression analysis of patient's survival.</p>

10.1158/2326-6066.27026429.v1 preprint EN 2024-09-16
 Supplementary Figure 6 from Regional variation in the tumor microenvironment, immune escape and prognostic factors in breast cancer in sub-Saharan Africa
OPENALEX - Publications 
Marcus Bauer Martina Vetter Kathrin Stückrath Meron Yohannes Zelalem Desalegn and 27 more Tewodros Yalew Yonas Bekuretsion Tariku W. Kenea Maureen Joffe Eunice J. van den Berg Julien I. Nikulu Bakarou Kamaté Shyam S. Manraj Olufemi J. Ogunbiyi Ima-Obong Ekanem Festus Igbinoba Mohenou Diomande Clement Adebamowo Charles P. Dzamalala Angelica A. Anele Annelle Zietsman Moses Galukande Milena Foerster Isabel dos‐Santos‐Silva Biying Liu Pablo Santos Ahmedin Jemal Tamrat Abebe Claudia Wickenhauser Barbara Seliger Valerie McCormack Eva Johanna Kantelhardt

<p>Figure S6: Multivariate Cox regression analysis of patient's survival.</p>

10.1158/2326-6066.27026429 preprint EN 2024-09-16
 Supplementary Figure 6 from Regional Variation in the Tumor Microenvironment, Immune Escape and Prognostic Factors in Breast Cancer in Sub-Saharan Africa
OPENALEX - Publications 
Marcus Bauer Martina Vetter Kathrin Stückrath Meron Yohannes Zelalem Desalegn and 27 more Tewodros Yalew Yonas Bekuretsion Tariku W. Kenea Maureen Joffe Eunice J. van den Berg Julien I. Nikulu Bakarou Kamaté Shyam S. Manraj Olufemi J. Ogunbiyi Ima-Obong Ekanem Festus Igbinoba Mohenou Diomande Clement Adebamowo Charles P. Dzamalala Angelica A. Anele Annelle Zietsman Moses Galukande Milena Foerster Isabel dos‐Santos‐Silva Biying Liu Pablo Santos Ahmedin Jemal Tamrat Abebe Claudia Wickenhauser Barbara Seliger Valerie McCormack Eva Johanna Kantelhardt

<p>Figure S6: Multivariate Cox regression analysis of patient's survival.</p>

10.1158/2326-6066.23283420 preprint EN cc-by 2023-06-02
 Supplementary Figure 3 from Regional Variation in the Tumor Microenvironment, Immune Escape and Prognostic Factors in Breast Cancer in Sub-Saharan Africa
OPENALEX - Publications 
Marcus Bauer Martina Vetter Kathrin Stückrath Meron Yohannes Zelalem Desalegn and 27 more Tewodros Yalew Yonas Bekuretsion Tariku W. Kenea Maureen Joffe Eunice J. van den Berg Julien I. Nikulu Bakarou Kamaté Shyam S. Manraj Olufemi J. Ogunbiyi Ima-Obong Ekanem Festus Igbinoba Mohenou Diomande Clement Adebamowo Charles P. Dzamalala Angelica A. Anele Annelle Zietsman Moses Galukande Milena Foerster Isabel dos‐Santos‐Silva Biying Liu Pablo Santos Ahmedin Jemal Tamrat Abebe Claudia Wickenhauser Barbara Seliger Valerie McCormack Eva Johanna Kantelhardt

<p>Figure S3: Immune cell subpopulations in SSA</p>

10.1158/2326-6066.23283429 preprint FR cc-by 2023-06-02
 Supplementary Figure 4 from Regional Variation in the Tumor Microenvironment, Immune Escape and Prognostic Factors in Breast Cancer in Sub-Saharan Africa
OPENALEX - Publications 
Marcus Bauer Martina Vetter Kathrin Stückrath Meron Yohannes Zelalem Desalegn and 27 more Tewodros Yalew Yonas Bekuretsion Tariku W. Kenea Maureen Joffe Eunice J. van den Berg Julien I. Nikulu Bakarou Kamaté Shyam S. Manraj Olufemi J. Ogunbiyi Ima-Obong Ekanem Festus Igbinoba Mohenou Diomande Clement Adebamowo Charles P. Dzamalala Angelica A. Anele Annelle Zietsman Moses Galukande Milena Foerster Isabel dos‐Santos‐Silva Biying Liu Pablo Santos Ahmedin Jemal Tamrat Abebe Claudia Wickenhauser Barbara Seliger Valerie McCormack Eva Johanna Kantelhardt

<p>Figure S4:PD-L1 expression and cytotoxicity</p>

10.1158/2326-6066.23283426 preprint EN cc-by 2023-06-02
Coming Soon ...