A5062766951- Cancer Immunotherapy and Biomarkers
- Immunotherapy and Immune Responses
- Ferroptosis and cancer prognosis
- Cancer Genomics and Diagnostics
- Global Cancer Incidence and Screening
- Cervical Cancer and HPV Research
- Circular RNAs in diseases
- Viral-associated cancers and disorders
- Lymphoma Diagnosis and Treatment
- Acute Lymphoblastic Leukemia research
- Colorectal Cancer Screening and Detection
- Genital Health and Disease
- AI in cancer detection
- Lymphadenopathy Diagnosis and Analysis
- Reproductive Health and Contraception
- Adolescent Sexual and Reproductive Health
- Oral and Maxillofacial Pathology
- Poverty, Education, and Child Welfare
- BRCA gene mutations in cancer
- Prostate Cancer Treatment and Research
- Gynecological conditions and treatments
- Dermatological and Skeletal Disorders
- Infectious Diseases and Mycology
- Pneumocystis jirovecii pneumonia detection and treatment
- Head and Neck Cancer Studies
University of Calabar
2015-2025
Federal Ministry of Health
2021
Institute of Human Virology
2016
London School of Hygiene & Tropical Medicine
2016
University of Abuja Teaching Hospital
2016
National Hospital Abuja
2016
University of Maryland, Baltimore
2016
PURPOSE The number of patients with childhood cancer (CC) in sub-Saharan Africa is expected to rise over the coming years. According WHO Initiative for Childhood Cancer, access care crucial and must be guided by needs their families. Our study explored barriers CC treatment from a patient's perspective guide health providers. METHODS From February September 2021, we conducted multinational cross-sectional sample nine population-based registries countries. Inclusion criteria comprised...
Abstract Background Pathologists face major challenges in breast cancer diagnostics sub-Saharan Africa (SSA). The problems identified as impairing the quality of pathology reports are shortcomings equipment, organization and insufficiently qualified personnel. In addition, context cancer, immunohistochemistry (IHC) needs to be available for evaluation biomarkers. study presented, we aim describe current state order highlight unmet needs. Methods We obtained information on services within...
Abstract The low overall survival rates of patients with breast cancer in sub-Saharan Africa (SSA) are driven by regionally differing tumor biology, advanced stages at diagnosis, and limited access to therapy. However, it is not known whether regional differences the composition microenvironment (TME) exist affect patients’ prognosis. In this international, multicentre cohort study, 1,237 formalin-fixed, paraffin-embedded samples, including samples “African Breast Cancer-Disparities Outcomes...
Abstract Background and Objectives Prostate cancer is the most commonly diagnosed in Nigerian men despite lack of PSA based screening. Current prevalence estimates Nigeria are on registry data obtained primarily from hospital admissions therefore not truly reflective prostate incidence. Prior autopsy series did adhere to modern pathologic quality practices. The aim this study was explore asymptomatic among at time autopsy. Methods Prostates were collected Universities Lagos Calabar Teaching...
Context: There has been a steady rise in Nigeria's HIV/AIDS burden since the first sero-prevalence survey 1991. economy is mainly dependent on oil that comes from Niger Delta Region. The majority of people delta region depend fishing and farming for livelihood. Years exploration activities with frequent spillages have led to severe environmental degradation resultant destruction farmlands aquatic flora fauna. situation characterised by poverty, high fertility disease. Issue: Oil become, doom...
Context: The incidence of induced abortion and the associated health risks are high in Calabar, Nigeria. There is need to confirm whether all women subjected these procedures really pregnant. Objective: To determine what proportion seeking services Calabar were Design Setting: Cross sectional study on who seek obtain services. capital River State South-Eastern part Subjects Methods: Women sought obtained abortions during period recruited into study. products conception from sent for...
Material and methods A five year retrospective study was carried out to review the frequency of diagnosis three tumours classified as AIDS defining malignancies (Kaposi sarcoma, non Hodgkin lymphoma, cervical cancer) one malignancy (squamous cell carcinoma conjunctiva), also commonly diagnosed in these patients. Records patients which are histologically confirmed between 1 January 2005 31 2009 were sorted their retroviral status classified.
Welcome to Annals of Global Health,Annals Health is a peer-reviewed, fully open access, online journal dedicated publishing high quality articles all aspects global health. The journal's mission advance health, promote research, and foster the prevention treatment disease worldwide. Its goals are improve health well-being people, equity, wise stewardship earth's environment. latest impact factor 3.64.Annals supported by Program for Public Common Good at Boston College. It was founded in 1934...
Triple negative breast cancer (TNBC) is an aggressive subtype that disproportionately affects women of African ancestry (WAA) and often associated with poor survival. Although there a high prevalence TNBC across West Africa in the diaspora, has been no comprehensive genomics study to investigate mutational profile ancestrally related Caribbean Africa.This multisite cross-sectional used 31 formalin-fixed paraffin-embedded (FFPE) samples from Barbadian Nigerian participants. High-resolution...
<p>Figure S1: Consort diagram of the analyzed samples</p>
<p>Figure S1: Consort diagram of the analyzed samples</p>
<p>Figure S2: TILs in SSA</p>
<p>Figure S3: Immune cell subpopulations in SSA</p>
<p>Figure S2: TILs in SSA</p>
<p>Figure S4:PD-L1 expression and cytotoxicity</p>
<p>Figure S3: Immune cell subpopulations in SSA</p>
<p>Figure S5: MHC I expression in SSA</p>
<p>Figure S4:PD-L1 expression and cytotoxicity</p>
<p>Figure S5: MHC I expression in SSA</p>
<p>Figure S6: Multivariate Cox regression analysis of patient's survival.</p>
<p>Figure S6: Multivariate Cox regression analysis of patient's survival.</p>