- EEG and Brain-Computer Interfaces
- Functional Brain Connectivity Studies
- Neural dynamics and brain function
- Neural and Behavioral Psychology Studies
- Advanced X-ray and CT Imaging
- Medical Imaging Techniques and Applications
- Neuroscience and Music Perception
- Neurobiology of Language and Bilingualism
- Sleep and Wakefulness Research
- Epigenetics and DNA Methylation
- Particle Detector Development and Performance
- Psychosomatic Disorders and Their Treatments
- Advanced Neuroimaging Techniques and Applications
- Nuclear Physics and Applications
- Advanced X-ray Imaging Techniques
- Mental Health Research Topics
- Schizophrenia research and treatment
- Reading and Literacy Development
- Radiation Dose and Imaging
- Blind Source Separation Techniques
- Radiation Detection and Scintillator Technologies
- Face Recognition and Perception
- Mass Spectrometry Techniques and Applications
- Attention Deficit Hyperactivity Disorder
- Analytical Chemistry and Chromatography
University of Bern
2016-2025
Martin Luther University Halle-Wittenberg
2025
University Hospital of Bern
2013-2024
Karolinska Institutet
2023
Children's Hospital of Los Angeles
2023
RWTH Aachen University
2023
Cuban Neuroscience Center
2001-2022
Mayo Clinic in Florida
2020
WinnMed
2019
Medizinische Hochschule Hannover
2014-2018
The origin of auditory hallucinations, which are one the core symptoms schizophrenia, is still a matter debate. It has been hypothesized that alterations in connectivity between frontal and parietotemporal speech-related areas might contribute to pathogenesis hallucinations. These networks assumed become dysfunctional during generation monitoring inner speech. Magnetic resonance diffusion tensor imaging relatively new vivo method investigate directionality cortical white tracts.To...
We present a program (Ragu; Randomization Graphical User interface) for statistical analyses of multichannel event-related EEG and MEG experiments. Based on measures scalp field differences including all sensors, using powerful, assumption-free randomization statistics, the yields robust, physiologically meaningful conclusions based entire, untransformed, unbiased set measurements. Ragu accommodates up to two within-subject factors one between-subject factor with multiple levels each....
Abstract BACKGROUND Epi proColon® is a new blood-based colorectal cancer (CRC) screening test designed to determine the methylation status of promoter region SEPT9 (septin 9) gene in cell-free DNA isolated from plasma. We describe analytical and clinical performance test. METHODS Analytical at 4 testing laboratories included determination limit detection, precision, reproducibility Clinical was evaluated prospective study by use samples (n = 1544) subjects enrolled PRESEPT trial. Results...
We review the theory and algorithms of electrophysiological brain connectivity analysis. This tutorial is aimed at providing an introduction to functional from signals, including electroencephalography, magnetoencephalography, electrocorticography, stereoelectroencephalography. Various estimators are discussed, introduced. Important issues for estimating mapping with electrophysiology discussed.
Semiconductor detector readout chips with pulse processing electronics have made possible spectroscopic X-ray imaging, bringing an improvement in the overall image quality and, case of medical a reduction dose delivered to patient. In this contribution we review state art semiconductor-detector ASICs for imaging emphasis on hybrid pixel technology. We discuss how some key challenges technology (such as dealing high fluxes, maintaining spectral fidelity, power consumption density) are...
Protein identification by tandem mass spectrometry is based on the reliable processing of acquired data. Unfortunately, generation a large number poor quality spectra commonly observed in LC-MS/MS, and these mostly noninformative with its associated costs should be avoided. We present continuous score that can computed very quickly considered an approximation MASCOT case correct identification. This used to reject low prior database identification, or draw attention those exhibit...
Background fMRI Resting State Networks (RSNs) have gained importance in the present literature. Although their functional role is unquestioned and physiological origin nowadays widely accepted, little known about relationship to neuronal activity. The combined recording of EEG allows temporal correlation between fluctuations RSNs dynamics spectral amplitudes. So far, only relationships several frequency bands some could be demonstrated, but no study accounted for spatial distribution domain...
Schizophrenia patients show abnormalities in a broad range of task demands. Therefore, an explanation common to all these has be sought independently any particular task, ideally the brain dynamics before takes place or during resting state. For neurobiological investigation such baseline states, EEG microstate analysis is particularly well suited, because it identifies subsecond global states stable connectivity patterns directly related recruitment different types information processing...
Synaptic dysfunction is the best anatomical correlate of early cognitive impairment in Alzheimer's disease (AD). Electroencephalography (EEG) directly reflects brain electrical activity at level synapses. The aim present study was to investigate correlations quantitative EEG measures, global field power (GFP) and synchronization (GFS), with conventional cerebrospinal fluid (CSF) biomarkers neurodegeneration patients diagnosed subjective decline (n = 210), mild 230), AD 197). Decreased CSF...