Masafumi Yoshimura

ORCID: 0000-0003-4846-5037
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About
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Research Areas
  • Functional Brain Connectivity Studies
  • EEG and Brain-Computer Interfaces
  • Neural dynamics and brain function
  • Sports Performance and Training
  • Sports injuries and prevention
  • Lower Extremity Biomechanics and Pathologies
  • Glycosylation and Glycoproteins Research
  • Neural and Behavioral Psychology Studies
  • Transcranial Magnetic Stimulation Studies
  • Sports Analytics and Performance
  • Brain Tumor Detection and Classification
  • Osteoarthritis Treatment and Mechanisms
  • Sports Dynamics and Biomechanics
  • Knee injuries and reconstruction techniques
  • Sport Psychology and Performance
  • Dementia and Cognitive Impairment Research
  • Schizophrenia research and treatment
  • Carbohydrate Chemistry and Synthesis
  • Winter Sports Injuries and Performance
  • Neurological Disease Mechanisms and Treatments
  • Treatment of Major Depression
  • Occupational Health and Performance
  • Neurological disorders and treatments
  • Monoclonal and Polyclonal Antibodies Research
  • Musculoskeletal pain and rehabilitation

Kansai Medical University
2016-2025

Juntendo University
2015-2024

Juntendo University Hospital
2016-2024

University Hospital of Bern
2007

Kumamoto University
1998

Osaka University
1994-1998

Jichi Medical University
1996

Osaka Medical Center for Cancer and Cardiovascular Diseases
1991

Kureha (Japan)
1989

University of Toronto
1989

Introduction of the β1-4 N-acetylglucosaminyltransferase (GnT-III) gene was reported to suppress metastasis in highly metastatic B16-hm murine melanoma cells (Yoshimura, M., Nishikawa, A., Ihara, Y., Taniguchi, S., and N. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 8754-8758). In this study, effect GnT-III transfer on E-cadherin studied, since acts as a suppressor metastasis. expression at cell-cell contacts expressing high activity greater than controls without affecting transcription....

10.1074/jbc.271.23.13811 article EN cc-by Journal of Biological Chemistry 1996-06-01

The fifth metatarsal bone is a common site of stress fractures in soccer athletes. Although several endocrine risk factors for have been proposed, the risks (5-MT) not evaluated.To evaluate fractures, we conducted cumulative case-control study. present study included 37 athletes, which 18 had history zone 2 or 3 fracture and 19 controls. We analyzed serum 25-hydroxyvitamin D (25-OHD), parathyroid hormone (PTH), as well biochemical markers turnover by univariate multivariate analyses.Logistic...

10.1177/1071100715617042 article EN Foot & Ankle International 2015-11-23

Efficient learning methods are important for cognitive rehabilitation. Studies have compared the benefits of errorless and trial-and-error (T&E) methods, focusing primarily on memory functions. Executive function related to error management has also been implicated in underlying processes needed T&E method, although few studies addressed this issue. Herein, further investigate adaptation involving executive function, we developed an experimental execution task correction process (i.e., chip...

10.1080/23279095.2025.2466831 article EN Applied Neuropsychology Adult 2025-02-15

Internal fixation is advocated as the primary treatment for fifth metatarsal Jones fractures in athletes; however, screw insertion site discomfort and refracture can occur especially competitive athletes. The ideal implant has not been determined.Headless compression of proximal an effective approach athletes.Case series; Evidence level, 4.We studied 60 athletes treated surgically with a headless (mean age, 19 years). mean follow-up time was 178 weeks. We evaluated clinical radiographic...

10.1177/0363546512459460 article EN The American Journal of Sports Medicine 2012-09-18

To explore brain functions in schizophrenic patients, the global analytic strategy of multichannel EEG was performed that combines measures complexity (Omega), total power (Sigma) and generalized frequency (Phi), microstate analysis applied to data for 24 nonmedicated patients healthy subjects. The had higher Omega Sigma values, lower Phi values compared with Three topographical classes were obtained from all by analysis. mean duration one class shortened These results indicated looser...

10.1159/000098264 article EN Neuropsychobiology 2006-01-01

There are inconsistent reports regarding the caudate nucleus volume in patients with schizophrenia compared healthy subjects. The reason for this is that neuroleptic medication may affect of schizophrenic patients. To clarify which antipsychotic changes schizophrenia, we measured volumes grey and white matter Ten were examined twice by magnetic resonance imaging (MRI) to measure nucleus. After first MRI examination, all treated olanzapine. clinical responses evaluated positive negative...

10.1159/000103575 article EN Neuropsychobiology 2007-01-01

The aim of this paper is to investigate cortical electric neuronal activity as an indicator brain function, in a mental arithmetic task that requires sustained attention, compared the resting state condition. two questions interest are localization different oscillatory activities, and directional effective flow between regions interest, condition state. In particular, theta alpha here, due their important role attention processing.We adapted ask study. Eyes closed 61-channel EEG was...

10.1016/j.cnp.2017.09.002 article EN cc-by-nc-nd Clinical Neurophysiology Practice 2017-01-01

A brain microstate is characterized by a unique, fixed spatial distribution of electrically active neurons with time varying amplitude. It hypothesized that implements functional/physiological state the during which specific neural computations are performed. Based on this hypothesis, electrical activity modeled as sequence non-overlapping microstates variable, finite durations (Lehmann and Skrandies 1980, 1984; Lehmann et al 1987). In study, EEG recordings from 109 participants eyes closed...

10.48550/arxiv.1411.1949 preprint EN cc-by-nc-sa arXiv (Cornell University) 2014-01-01

A brain microstate is characterized by a unique, fixed spatial distribution of electrically active neurons with time varying amplitude. It hypothesized that implements functional/physiological state the during which specific neural computations are performed. Based on this hypothesis, electrical activity modeled as sequence non-overlapping microstates variable, finite durations (Lehmann and Skrandies 1980, 1984; Lehmann et al 1987). In study, EEG recordings from 109 participants eyes closed...

10.5167/uzh-100596 preprint EN arXiv (Cornell University) 2014-11-07

1. Abstract EEG/MEG neuroimaging consists of estimating the cortical distribution time varying signals electric neuronal activity, for study functional localization and connectivity. Currently, many different imaging methods are being used, with very capabilities correct activity The aim here is to provide a guideline choosing best (i.e. least bad) method. This first limited comparison following EEG signals: sLORETA eLORETA (standardized exact low resolution electromagnetic tomography), MNE...

10.1101/269753 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2018-02-22

It is critical to develop accurate and universally available biomarkers for dementia diseases appropriately deal with the problems under world-wide rapid increasing of patients dementia. In this sense, electroencephalography (EEG) has been utilized as a promising examination screen assist in diagnosing dementia, advantages sensitiveness neural functions, inexpensiveness, high availability. Moreover, algorithm-based deep learning can expand EEG applicability, yielding automatic classification...

10.1159/000528439 article EN Neuropsychobiology 2023-01-01

N -Acetylglucosaminyltransferase III (GnT-III) produces “bisecting-GlcNAc” and regulates the branching of N-glycans. GnT-III activity is elevated during hepatocarcinogenesis, which in contrast to undetectable level found normal hepatocytes. To determine biological significance hepatocytes, transgenic mice that specifically express liver were established characterized. The hepatocytes had a swollen oval-like morphology, with many lipid droplets. Apolipoprotein B, contained increased...

10.1073/pnas.95.5.2526 article EN Proceedings of the National Academy of Sciences 1998-03-03

The problem of interest here is the study brain functional and effective connectivity based on non-invasive EEG-MEG inverse solution time series. These signals generally have low spatial resolution, such that an estimated signal at any one site instantaneous linear mixture true, actual, unobserved across all cortical sites. False can result from analysis these low-resolution signals. Recent efforts toward "unmixing" been developed, under name "leakage correction". One recent noteworthy...

10.1101/178657 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2017-08-20

<b><i>Purpose:</i></b> The aim of this study was to compare the effects risperidone long-acting injection (RLAI) and paliperidone palmitate (PP) on non-acute-phase social functioning in patients with schizophrenia. <b><i>Patients Methods:</i></b> In 6-month pilot, open-label, randomized controlled study, 30 schizophrenia who had been treated RLAI were randomly allocated continuation group or switched PP group. Patients evaluated at baseline 6...

10.1159/000442209 article EN Neuropsychobiology 2016-01-01

The left dorsolateral prefrontal cortex (lDLPFC) is a commonly targeted brain region for repetitive transcranial magnetic stimulation (rTMS) depression. lDLPFC has been identified using the "5-cm rule." However, identification of may deviate from ideal site localized by neuronavigation. Therefore, we aimed to compare this method with other methods and examine relationship between deviation treatment effects. While most existing studies have focused on participants European descent, study...

10.1159/000541006 article EN Neuropsychobiology 2024-10-07
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