A5103168343- Functional Brain Connectivity Studies
- EEG and Brain-Computer Interfaces
- Neural dynamics and brain function
- Transcranial Magnetic Stimulation Studies
- Neural and Behavioral Psychology Studies
- Cerebrospinal fluid and hydrocephalus
- Traumatic Brain Injury and Neurovascular Disturbances
- Obsessive-Compulsive Spectrum Disorders
- Mindfulness and Compassion Interventions
- Psychedelics and Drug Studies
- Neurological disorders and treatments
- Neurosurgical Procedures and Complications
- Advanced MRI Techniques and Applications
- Brain Tumor Detection and Classification
- Optical Imaging and Spectroscopy Techniques
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Diet and metabolism studies
- Psychosomatic Disorders and Their Treatments
- Creativity in Education and Neuroscience
- Dementia and Cognitive Impairment Research
- Chemical synthesis and alkaloids
- Fetal and Pediatric Neurological Disorders
- Mind wandering and attention
- Neurotransmitter Receptor Influence on Behavior
- Restraint-Related Deaths
Kansai Medical University
2016-2024
University Hospital of Bern
2017-2018
Osaka University
2011-2017
University of Bern
2017
Osaka City General Hospital
2013
Osaka Prefectural Medical Center
2013
To explore neurophysiological biomarkers of Alzheimer's disease (AD), we investigated electroencephalography (EEG) AD patients, and assessed lagged phase synchronization, a measure brain functional connectivity. Twenty-eight probable patients 30 healthy controls (HC) were enrolled. Forty seconds artifact-free EEG data selected compared between with HC. Current source density (CSD) synchronization analyzed by using eLORETA. Patients showed significantly decreased most cortical regions in...
It is unclear whether, like in schizophrenia, psychosis-related disruption connectivity between certain regions, as an index of intrinsic functional disintegration, occurs schizophrenia-like psychosis epilepsy (SLPE). In this study, we sought to determine abnormal patterns resting-state EEG oscillations and patients with SLPE, compared nonpsychotic patients, assess correlations psychopathological deficits.Resting was recorded 21 focal SLPE clinically-matched non-psychotic controls. Source...
Frontal midline theta rhythm (Fmθ) appears widely distributed over medial prefrontal areas in EEG recordings, indicating focused attention. Although mental calculation is often used as an attention-demanding task, little has been reported on calculation-related activation Fmθ experiments. In this study we spatially filtered MEG and permutation analysis to precisely localize cortical generators of the magnetic counterpart Fmθ, well other sources oscillatory activity associated with processing...
Recent functional magnetic resonance imaging (fMRI) studies have shown that networks can be extracted even from resting state data, the so called "Resting State independent Networks" (RS-independent-Ns) by applying component analysis (ICA). However, compared to fMRI, electroencephalography (EEG) and magnetoencephalography (MEG) much higher temporal resolution provide a direct estimation of cortical activity. To date, MEG applied ICA for separate frequency bands only, disregarding...
The aim of this paper is to investigate cortical electric neuronal activity as an indicator brain function, in a mental arithmetic task that requires sustained attention, compared the resting state condition. two questions interest are localization different oscillatory activities, and directional effective flow between regions interest, condition state. In particular, theta alpha here, due their important role attention processing.We adapted ask study. Eyes closed 61-channel EEG was...
It is critical to develop accurate and universally available biomarkers for dementia diseases appropriately deal with the problems under world-wide rapid increasing of patients dementia. In this sense, electroencephalography (EEG) has been utilized as a promising examination screen assist in diagnosing dementia, advantages sensitiveness neural functions, inexpensiveness, high availability. Moreover, algorithm-based deep learning can expand EEG applicability, yielding automatic classification...
Emotion regulation is the process that adjusts type or amount of emotion when we experience an emotional situation. The aim this study was to reveal quantitative changes in brain activity during information processing related psychosomatic states and determine electrophysiological features neuroticism. Twenty-two healthy subjects (mean age 25 years, 14 males 8 females) were registered. Electroencephalography (EEG) measured audiovisual memory task under three conditions (neutral, pleasant...
This study registered consecutive cases to elucidate the efficacy of rTMS treatment for depression within Japanese public health insurance system. Of 102 patients with who received over left dorsolateral prefrontal cortex, 44 (43.1%) reached remission and 14 (13.7%) did not reach but responded treatment. No serious adverse events occurred. Low baseline HAMD-17 score was associated after Favorable outcomes were shown in this cohort Our results provide insights into real-world clinical setting.
The left dorsolateral prefrontal cortex (lDLPFC) is a commonly targeted brain region for repetitive transcranial magnetic stimulation (rTMS) depression. lDLPFC has been identified using the "5-cm rule." However, identification of may deviate from ideal site localized by neuronavigation. Therefore, we aimed to compare this method with other methods and examine relationship between deviation treatment effects. While most existing studies have focused on participants European descent, study...
Background Liver regeneration (LR) involves an early inductive phase characterized by the proliferation of hepatocytes, and a delayed angiogenic distinguished expansion non-parenchymal compartment. The interest in understanding mechanism LR has lately shifted from growth parenchymal cells to vascular remodeling during LR. Angiogenesis accompanied exerts pivotal role accomplish process. Vascular endothelial factor (VEGF) been elucidated as most dynamic regulator angiogenesis. From this...
Transcranial direct current stimulation is a promising neuromodulation method for treating depression. However, compared with pharmacological treatment, previous studies have reported that relatively limited proportion of patients respond to tDCS treatment. In addition, the neurophysiological mechanisms underlying treatment remain unclear, making it difficult identify response predictors based on function. Because effects are achieved by repetitive application tDCS, studying immediate in...
Recently, cerebrospinal fluid (CSF) biomarkers related to Alzheimer’s disease (AD) have garnered a lot of clinical attention. To explore neurophysiological traits AD and parameters for its diagnosis, we examined the association between CSF electroencephalography (EEG) in 14 probable patients. Using exact low-resolution electromagnetic tomography (eLORETA), artifact-free 40-sesond EEG data were estimated with current source density (CSD) lagged phase synchronization (LPS) as parameters....
The aim of this study was to investigate the changes brain electric field induced by symptom provocation in patients with obsessive-compulsive disorder (OCD) comparison healthy controls resting state. For purpose, EEG recordings conditions initial rest, clean control, imaginal exposure, and final rest were used for computing spatiotemporal activity characteristics based on microstate segmentation. Within-group comparisons significant condition: OCD showed high global power (GFP) transition...
Idiopathic normal pressure hydrocephalus (iNPH) is a neuropsychiatric syndrome characterized by gait disturbance, cognitive impairment and urinary incontinence that affect elderly individuals. These symptoms can potentially be reversed cerebrospinal fluid (CSF) drainage or shunt operation. Prior to operation, of small amount CSF "CSF tapping" usually performed ascertain the effect Unfortunately, conventional neuroimaging methods such as single photon emission computed tomography (SPECT)...
Variance of state variables shifts due to phase-instability and may serve as an early-warning signal phase transition complex systems such epileptic seizure brain cortical activity. Neuronal Activity Topology (NAT) analysis calculates a normalized-power-variance (NPV) electroencephalogram (EEG) data in each frequency band obtain relative values comparable among different power states. In this study, using AT analysis, we investigated PV changes between the pre-ictal ictal patient with mesial...
Idiopathic normal pressure hydrocephalus (iNPH) is a syndrome characterized by gait disturbance, cognitive deterioration and urinary incontinence in elderly individuals. These symptoms can be improved shunt operation some but not all patients. Therefore, discovering predictive factors for the surgical outcome of great clinical importance. We used normalized power variance (NPV) electroencephalography (EEG) waves, sensitive measure instability cortical electrical activity found significantly...
Neurophysiological changes related to meditation have recently attracted scientific attention. We aimed detect in electroencephalography (EEG) parameters induced by a meditative intervention subjects with post-traumatic residual disability (PTRD), which has been confirmed for effectiveness and safety previous study. This will allow us estimate the objective effect of this at neurophysiological level. Ten PTRD were recruited underwent psychological assessment EEG recordings before after...
Exact low-resolution brain electromagnetic tomography (eLORETA) is a technique for three-dimensional representation of the distribution sources electrical activity in brain. Kurtosis analysis allows identification spiky To evaluate reliability eLORETA kurtosis analysis, results were compared with those equivalent current dipole (ECD) and synthetic aperture magnetometry (SAM) magnetoencephalography (MEG) data patient epilepsy elementary visual seizures 6-year follow-up. The...
<b><i>Objectives:</i></b> eLORETA (exact low-resolution brain electromagnetic tomography) is a technique created by Pascual-Marqui et al. [Int J Psychophysiol. 1994 Oct; 18(1): 49–65] for the 3-dimensional representation of current source density in electroencephalography (EEG) data. Kurtosis analysis allows identification spiky activity brain. In this study, we focused on evaluation reliability kurtosis analysis. For purpose, results localization paroxysmal EEG were...