A5013935560- Synthesis and Catalytic Reactions
- Chemical Synthesis and Analysis
- Particle Accelerators and Free-Electron Lasers
- Fungal and yeast genetics research
- Particle accelerators and beam dynamics
- Biocrusts and Microbial Ecology
- Pigment Synthesis and Properties
- Synthesis and Characterization of Heterocyclic Compounds
- Dyeing and Modifying Textile Fibers
- Synthesis of β-Lactam Compounds
- Genomics and Phylogenetic Studies
- Microbial Natural Products and Biosynthesis
- Catalytic Processes in Materials Science
- Thin-Film Transistor Technologies
- biodegradable polymer synthesis and properties
- Gyrotron and Vacuum Electronics Research
- Catalysts for Methane Reforming
- Polymer Nanocomposites and Properties
- Protein Hydrolysis and Bioactive Peptides
- Semiconductor Lasers and Optical Devices
- Magnesium Alloys: Properties and Applications
- Aluminum Alloys Composites Properties
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- RNA and protein synthesis mechanisms
- 2D Materials and Applications
Osaka University
2019-2024
College of Industrial Technology
2023-2024
Nihon University
2008-2024
Osaka Gas (Japan)
2024
Shizuoka Institute of Science and Technology
2024
Tokyo Metropolitan University
2022-2023
National Agriculture and Food Research Organization
2018-2022
The University of Tokyo
2022
Kochi University of Technology
2022
National Institute for Agro-Environmental Sciences
2021-2022
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMammalian chymotrypsin-like enzymes. Comparative reactivities of rat mast cell proteases, human and dog skin chymases, cathepsin G with peptide 4-nitroanilide substrates chloromethyl ketone sulfonyl fluoride inhibitorsJames C. Powers, Takumi Tanaka, J. Wade Harper, Yoshihiro Minematsu, Larry Barker, Danforth Lincoln, Katherine V. Crumley, Jorma E. Fraki, Norman M. Schechter, Cite this: Biochemistry 1985, 24, 8, 2048–2058Publication Date...
Photodimerization of maleic anhydride (MA) gives insoluble precipitated products that can be a trigger to clog conventional microreactor. To avoid this problem, we devised microreactor uses liquid/gas slug flow and ultrasonication. Inert N2 gas introduced into the reaction solution swept through reactor tube transported in liquid segments.Ultrasound vibrations inhibited adhesion sedimentation precipitate tube. The combination ultrasound prevented from clogging. Fluorinated ethylene propylene...
The subsite specificity of human lung and skin tryptase (trypsin-like enzyme) has been studied at pH 7.5 using 17 amino acid dipeptide thioester substrates 14 tripeptide 4-nitroanilide substrates. reactivity the tryptases were compared with bovine trypsin other trypsin-like enzymes. Neither was similar to either kallikrein or factor XIIa (Hageman factor). enzyme most reactive as measured by constant kcat/KM. best substrate benzyloxycarbonyl(Z)-Lys-Arg-S-CH2CH(CH3)2 which had a kcat/KM value...
Lithium L-aziridine-2-carboxylate was synthesized from N-trityl-L-aziridine-carboxylic acid benzyl ester by the treatment with trifluoroacetic followed saponification lithium hydroxide. Several N-acylaziridine-2-carboxylic esters were in good yield.
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTHuman leukocyte cathepsin G. Subsite mapping with 4-nitroanilides, chemical modification, and effect of possible cofactorsTakumi Tanaka, Yoshihiro Minematsu, Christopher F. Reilly, James Travis, C. PowersCite this: Biochemistry 1985, 24, 8, 2040–2047Publication Date (Print):April 9, 1985Publication History Published online1 May 2002Published inissue 9 April...
Monolayers of transition metal dichalcogenides (TMDs) are an ideal 2D platform for studying a wide variety electronic properties and potential applications due to their chemical diversity. Similarly, single-walled TMD nanotubes (SW-TMDNTs)-seamless cylinders rolled-up monolayers-are 1D materials that can exhibit tunable depending on both chirality composition. However, much less has been explored about geometrical structures variations instability under ambient conditions. Here, the...
Atomically flat, sputter-grown Au(111) films allowed well-ordered alkanethiol (exemplified by octanethiol) monolayers to be self-assembled from solution markedly faster and in larger domain sizes than previously reported. An X-ray photoelectron spectroscopy analysis showed that complete monolayer coverage was reached 0.2−60 min of incubation 0.1−0.001 mM ethanolic at room temperature (∼17 °C), with single-step (0.1 0.01 mM) or two-step (0.001 adsorption kinetics. Increasing the 35 °C enough...
The three quantitative trait loci (qSH1, qSH3, and qSH4) causing reduction of seed shattering were investigated to examine their relative importance during rice domestication. qSH1 qSH4 showed a distinct effect on the shattering, compared with qSH3 locus. Fine mapping sequence analysis strongly suggested that are same as recently reported genes. A non-shattering allele at drastically changed phenotype even in presence alleles loci, showing is genetically epistatic other loci. level diversity...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTActive-site mapping of bovine and human blood coagulation serine proteases using synthetic peptide 4-nitroanilide thio ester substratesKyujin Cho, Takumi Tanaka, Robert R. Cook, Walter Kisiel, Kazuo Fujikawa, Kotoku Kurachi, James C. PowersCite this: Biochemistry 1984, 23, 4, 644–650Publication Date (Print):February 14, 1984Publication History Published online1 May 2002Published inissue 14 February...
Rolling two-dimensional (2D) materials into 1D nanotubes allows for greater functionality. Boron-nitride (BNNTs) can serve as insulating templates the coaxial growth of guest nanotubes, without interfering with property characterization. However, their application has been greatly hindered by poor dispersibility, inevitably resulting in formation thick bundles. Here we present facile preparation well-dispersed BNNT via surfactant dispersions and synthesis van der Waals heterostructures based...
The crystallization behavior of poly(ε-caprolactone) (PCL) chains (i.e., PCL block + homopolymer systems) spatially confined in nanocylinders with different diameters D has been investigated as a function the mole fraction homopolymers fhomo existing chains. inside were prepared using microphase separation PCL-block-polystyrene (PCL-b-PS) diblock copolymers photocleavable o-nitrobenzyl group (ONB) between and PS blocks, subsequently ONB was cleaved by controlled irradiation UV light to get...
Atopic dermatitis is a skin disease characterized by inflammation, pruritus, and chronic or relapsing eczematous lesions. Recently, ampholytic polysaccharide sacran has attracted particular focus of attention as novel biomaterial. In the present study, we investigated effect solution on atopic in clinical study. Almost all average scores for symptoms each patient treated with solutions were improved. addition, sleep disorder itching also significantly ameliorated treatment 4 weeks, compared...
It is critical to develop accurate and universally available biomarkers for dementia diseases appropriately deal with the problems under world-wide rapid increasing of patients dementia. In this sense, electroencephalography (EEG) has been utilized as a promising examination screen assist in diagnosing dementia, advantages sensitiveness neural functions, inexpensiveness, high availability. Moreover, algorithm-based deep learning can expand EEG applicability, yielding automatic classification...
Abstract Triarylbismuthines readily reacted with a catalytic amount of palladium(II) acetate in methanol under air to give the corresponding biaryls high yields. The presence oxygen was indispensable for this coupling, biaryl formation being quite slow nitrogen. Oxygen absorption observed during reaction and Pd-oxygen complex prepared separately worked effectively as reagent coupling even inert gas.
Abstract The reaction of Z–Gly–Azy–Gly–OBzl with amines was studied. With primary amines, the 1-acyl group (Z–Gly) aziridine peptide mainly migrated to reactant amine cleaving amide bond between glycine and aziridine, whereas aniline diethylamine gave diaminopropionic acid derivatives via ring opening reaction.
Abstract Actinomycin D (C1) has been synthesized by a route involving the ester formation between two peptide fragments, (2S,3S)-1-(2-nitro-3-benzyloxy-4-methylbenzoyl)-3-methyl-2-aziridinecarbonyl-d-valylproline t-butyl and N-benzyloxycarbonylsarcosyl-N-methylvaline, via ring-opening reaction of aziridine. Cyclization, followed reduction oxidation, gave actinomycin (C1). The synthetic was indistinguishable from natural substance as regards physical properties biological activity.
In all-solid-state batteries (ASSB), increasing the thickness of electrodes is essential for energy density. However, this limits C-rate performance, particularly with a large volume fraction active materials (AMs), transport ions in electrode hindered, leading to poor utilization AMs ASSBs. To accelerate development ASSBs, it highly desirable develop analytical methods understanding thick electrodes. paper, we propose novel impedance analysis method using transmission line model (TLM)...
Hydrophobins are amphipathic proteins secreted by filamentous fungi. When the industrial fungus Aspergillus oryzae is grown in a liquid medium containing polyester polybutylene succinate co-adipate (PBSA), it produces RolA, hydrophobin, and CutL1, PBSA-degrading cutinase. Secreted RolA attaches to surface of PBSA particles recruits which then condenses on stimulates hydrolysis PBSA. Here, we identified amino acid residues that required for RolA-CutL1 interaction using site-directed...