- Surfactants and Colloidal Systems
- Marine and fisheries research
- Electrostatics and Colloid Interactions
- Oral microbiology and periodontitis research
- Hydrogels: synthesis, properties, applications
- Photosynthetic Processes and Mechanisms
- Spectroscopy and Quantum Chemical Studies
- Food Industry and Aquatic Biology
- Plant Gene Expression Analysis
- Glycosylation and Glycoproteins Research
- Biopolymer Synthesis and Applications
- Prostate Cancer Diagnosis and Treatment
- Plant biochemistry and biosynthesis
- Chemical and Physical Properties in Aqueous Solutions
- Analytical Chemistry and Chromatography
- Synthetic Organic Chemistry Methods
- Thermodynamic properties of mixtures
- Prostate Cancer Treatment and Research
- Proteoglycans and glycosaminoglycans research
- Carbohydrate Chemistry and Synthesis
- biodegradable polymer synthesis and properties
- GABA and Rice Research
- Enzyme Structure and Function
- Photochemistry and Electron Transfer Studies
- Oral and gingival health research
University of Wisconsin–Madison
2016-2025
Juntendo University
2025
Kyowa Kirin (Japan)
2012-2024
Tokyo University of Agriculture and Technology
2011-2024
Yodogawa Christian Hospital
2015-2024
Madison Group (United States)
2023-2024
Juntendo University Hospital
2024
Kyoto Prefectural University of Medicine
2015-2023
Osaka Dental University
2017-2022
North Medical Center
2019
Accurate quantification of bacterial species in dental plaque is needed for microbiological diagnosis periodontal diseases. The present study was designed to assess the sensitivity, specificity and quantitativity real-time PCR using GeneAmp Sequence Detection System with two fluorescence chemistries. TaqMan probe reporter quencher dye, SYBR Green dye were used sources fluorescence. Primers probes Actinobacillus actinomycetemcomitans, Porphyromonas gingivalis, Prevotella intermedia total...
Abstract To test whether tocopherols (vitamin E) are essential in the protection against oxidative stress plants, a series of Arabidopsis thaliana vitamin E (vte) biosynthetic mutants that accumulate different types and levels pathway intermediates were analyzed under abiotic stress. Surprisingly subtle differences observed between tocopherol-deficient vte2 mutant wild type during high-light, salinity, drought stresses. However, vte2, to lesser extent vte1, exhibited dramatic phenotypes low...
Abstract l-Phe, a protein building block and precursor of numerous phenolic compounds, is synthesized from prephenate via an arogenate and/or phenylpyruvate route in which dehydratase (ADT) or dehydratase, respectively, plays key role. Here, we used Petunia hybrida flowers, are rich Phe-derived volatiles, to determine the biosynthetic routes involved Phe formation planta. Of three identified petunia ADTs, expression ADT1 was highest petals positively correlated with endogenous levels...
Summary Diverse natural products are synthesized in plants by specialized metabolic enzymes, which often lineage‐specific and derived from gene duplication followed functional divergence. However, little is known about the contribution of primary metabolism to evolution pathways. Betalain pigments, uniquely found plant order Caryophyllales, aromatic amino acid l ‐tyrosine (Tyr) replaced otherwise ubiquitous phenylalanine‐derived anthocyanins. This study combined biochemical, molecular...
Abstract The plant shikimate pathway directs bulk carbon flow toward biosynthesis of aromatic amino acids (AAAs, i.e. tyrosine, phenylalanine, and tryptophan) numerous phytochemicals. microbial is feedback inhibited by AAAs at the first enzyme, 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase (DHS). However, generally do not inhibit DHS activities from extracts how plants regulate remains elusive. Here, we characterized recombinant Arabidopsis thaliana DHSs (AthDHSs) found that tyrosine...
Abstract Objectives: Tumour necrosis factor‐ α (TNF‐ ) and interleukin‐1 β (IL‐1 participate in the establishment of inflammatory lesions periodontitis. High production these cytokines may relate to severity There have already been several studies examining association between periodontitis single nucleotide polymorphisms (SNPs) that affect cytokine productivity. Recently, new SNPs TNF‐α , −1031, −863 −857, variants which are observed a relatively large proportion Japanese, identified. The...
Abstract Tocopherols (vitamin E) are lipid-soluble antioxidants synthesized only by photosynthetic eukaryotes and some cyanobacteria, have been assumed to play important roles in protecting membranes from oxidative stress. To test this hypothesis, tocopherol-deficient mutants of Synechocystis sp. strain PCC 6803 (slr1736 slr1737 mutants) were challenged with a series reactive oxygen species-generating lipid peroxidation-inducing chemicals combination high-light (HL) intensity The wild type...