- Neural dynamics and brain function
- stochastic dynamics and bifurcation
- Nonlinear Dynamics and Pattern Formation
- Dementia and Cognitive Impairment Research
- EEG and Brain-Computer Interfaces
- Neural Networks and Applications
- Functional Brain Connectivity Studies
- Aortic Disease and Treatment Approaches
- Cerebrospinal fluid and hydrocephalus
- Control Systems and Identification
- Chaos control and synchronization
- Parkinson's Disease Mechanisms and Treatments
- Advanced Thermodynamics and Statistical Mechanics
- Aortic aneurysm repair treatments
- Probabilistic and Robust Engineering Design
- Congenital Heart Disease Studies
- Diffusion and Search Dynamics
- Neurosurgical Procedures and Complications
- Schizophrenia research and treatment
- Gene Regulatory Network Analysis
- Advanced Image and Video Retrieval Techniques
- Traumatic Brain Injury and Neurovascular Disturbances
- Botulinum Toxin and Related Neurological Disorders
- Scientific Research and Discoveries
- Spinal Cord Injury Research
Osaka University
2016-2025
Oji General Hospital
2025
Creative Commons
2023
Sapporo Medical University
2015-2023
Juntendo University Hospital
2021
Osaka City General Hospital
2020
Southern Tohoku General Hospital
2020
Osaka Prefectural Medical Center
2019-2020
Kyorin University
2017-2019
Nagoya University
2015-2017
A detailed study of the asymptotic behavior first-passage-time p.d.f. and its moments is carried out for an unrestricted conditional Ornstein-Uhlenbeck process a constant boundary. Explicit expressions are determined which include those earlier discussed by Sato [15] Nobile et al. [9]. In particular, it shown that can be expressed as sum exponential functions with negative exponents latter reduces to single density time increases, irrespective chosen The explicit obtained any order appear...
Behavioral and psychological symptoms of dementia (BPSDs) negatively impact the prognosis patients increase caregiver distress. The aims this study were to clarify differences trajectories 12 kinds BPSDs by disease severity in four major dementias develop charts showing frequency, severity, associated distress (ACD) using data a Japan multicenter (J-BIRD).We gathered Neuropsychiatric Inventory (NPI) with Alzheimer's (AD; n = 1091), Lewy bodies (DLB; 249), vascular (VaD; 156), frontotemporal...
ABSTRACT Objectives To evaluate the preoperative risk factors for early intravesical recurrence after radical nephroureterectomy (RNU) in patients with upper urinary tract carcinoma (UTUC) according to history of non‐muscle invasive bladder cancer (NMIBC). Methods We retrospectively evaluated who underwent RNU UTUC between 2012 and 2022 at 14 hospitals. Early was defined as pathologically confirmed within 1 year RNU. Patients received single‐dose immediate instillation (IVI) prevention were...
Abstract Background This study aimed to identify cases of potential prodromal DLB in very late-onset schizophrenia-like psychosis (VLOSLP), using indicative biomarkers dementia with Lewy bodies (DLB), and evaluate the characteristics as DLB. Methods Data patients VLOSLP without Parkinsonism, who underwent testing for at least one biomarker DLB, were retrospectively collected from database psychiatry clinic Osaka University Hospital. Patients divided into two groups based on positive...
There has been no systematic analysis of coping strategies for behavioral and psychological symptoms dementia (BPSD) using large-scale cumulative data. We preliminarily examined the characteristics successful unsuccessful BPSD. employed a deductive inductive (hybrid approach) data derived from "Ninchisho Chienowa-net," web-based system that collects caregivers' Antecedent control procedure consequence manipulation in applied behavior (ABA) were used as theory-driven codes classification....
<title>Abstract</title> Background Dual-task composed of gait or stepping tasks combined with cognitive has been well-established as valuable tools for detecting neurocognitive disorders such mild impairment and early-stage Alzheimer’s disease. We previously developed a novel dual-task system high accuracy differentiating patients from healthy controls. In this study, we aimed to elucidate whether the output value obtained through artificial intelligence assumptions clinical meaning other...
The algorithm given by Buonocore et al. [1] to evaluate first-passage-time p.d.f.’s for Wiener and Ornstein–Uhlenbeck processes through a time-dependent boundary is extended wide class of time-homogeneous one-dimensional diffusion processes. Several examples are thoroughly discussed along with some computational results.
This paper gives an asymptotic evaluation of the probability that Wiener path first crosses a square root boundary. The result is applied to estimate moments first-passage time distribution Ornstein–Uhlenbeck process constant
Background Sleep disturbances in Alzheimer disease (AD) may affect behavioral and psychological symptoms of dementia (BPSD). Our aim was to elucidate the associations between sleep other BPSD at different stages AD. Methods This investigation part a multicenter‐retrospective study Japan (J‐BIRD). Eligible for final analyses were 684 AD patients. Global severity estimated using Clinical Dementia Rating (CDR) scale. assessed Neuropsychiatric Inventory (NPI). We analyzed relationships according...
ABSTRACT Objectives: We aimed to investigate the association between very late-onset schizophrenia-like psychosis (VLOSLP), a schizophrenia spectrum disorder with an onset of ≥60 years, and Alzheimer’s disease (AD) using biomarkers. Design: Retrospective cross-sectional study. Setting: Neuropsychology clinic Osaka University Hospital in Japan. Participants: Thirty-three participants were classified into three groups: eight AD biomarker-negative VLOSLP (VLOSLP−AD), nine biomarker-positive...
Dementia with Lewy bodies (DLB) is characterized by progressive cognitive decline, fluctuating cognition, visual hallucinations, rapid eye movement sleep behavior disorder, and parkinsonism. DLB the second most common type of degenerative dementia all cases. However, DLB, particularly in early stage, underdiagnosed sometimes misdiagnosed other types dementia. Thus, it great interest investigating neurophysiological markers DLB.We introduced exact low-resolution brain electromagnetic...
Background: Although apathy is associated with damage to the frontal and temporal lobes in Alzheimer's disease (AD), crucial regions for patients amnestic mild cognitive impairment (aMCI) are unknown. Objective: To identify brain aMCI patients. M ethods: The subjects of this study were 98 who entered our dementia registry between March 1, 2009 April 30, 2015 satisfied criteria aMCI. association score Neuropsychiatric Inventory regional gray matter volume was analyzed using voxel-based...