A5007424237- Balance, Gait, and Falls Prevention
- Muscle activation and electromyography studies
- Neural dynamics and brain function
- Motor Control and Adaptation
- stochastic dynamics and bifurcation
- Nonlinear Dynamics and Pattern Formation
- Gene Regulatory Network Analysis
- EEG and Brain-Computer Interfaces
- Effects of Vibration on Health
- Transcranial Magnetic Stimulation Studies
- Robotic Locomotion and Control
- Neuroscience and Neural Engineering
- Microbial Metabolic Engineering and Bioproduction
- Advanced Numerical Analysis Techniques
- Ergonomics and Musculoskeletal Disorders
- Cerebral Palsy and Movement Disorders
- Fluid Dynamics and Vibration Analysis
- Chaos control and synchronization
- Gaze Tracking and Assistive Technology
- Gait Recognition and Analysis
- Visual perception and processing mechanisms
- Lattice Boltzmann Simulation Studies
- Parkinson's Disease Mechanisms and Treatments
- Cardiac electrophysiology and arrhythmias
- Wind and Air Flow Studies
Osaka University
2015-2024
Kyoto College of Graduate Studies for Informatics
2024
Kyoto University
2024
The University of Tokyo
1993-2018
Toyama Prefectural University
2004-2016
Fukuoka University
2014
Toyota Motor Corporation (Japan)
2014
Ritsumeikan University
2011
Nihon University
1997-2010
Peking University
2009
The main purpose of this study is to compare two different feedback controllers for the stabilization quiet standing in humans, taking into account that intrinsic ankle stiffness insufficient and there a large delay inducing instability loop: 1) standard linear, continuous-time PD controller 2) an intermittent characterized by switching function defined phase plane, with or without dead zone around nominal equilibrium state. stability analysis first carried out using tools linear control...
Human upright posture, as a mechanical system, is characterized by an instability of saddle type, involving both stable and unstable dynamic modes. The brain stabilizes such system generating active joint torques, according to time-delayed neural feedback control. What still unsolved clear understanding the control strategies mechanisms that are used central nervous in order stabilize posture robust way while maintaining flexibility. Most studies this direction have been limited single...
The time course of the center pressure (CoP) during human quiet standing, corresponding to body sway, is a stochastic process, influenced by variety features underlying neuro-musculo-skeletal system, such as postural stability and flexibility. Due complexity sway patterns have been characterized in an empirical way number indices, size mean velocity. Here, we describe statistical approach with aim estimating "universal" namely parameters that are independent individual characteristics thus...
Quantitative trait loci (QTLs) for a number of agronomically important traits perennial ryegrass ( Lolium perenne L.) were identified by means reference molecular marker‐based genetic map. Replicated phenotypic data was obtained field‐assessed morphological and developmental as well the winter hardiness‐associated characters survival electrical conductivity. Marker‐trait association analysis performed methods, high degree congruence observed between respective results. QTLs detected such...
Several radiological methods of measuring anteversion the acetabular component after total hip replacement (THR) have been described. These studies used different definitions and reference planes to compare methods, allowing for misinterpretation results. We compared reliability accuracy five current using plain radiographs (those Lewinnek, Widmer, Liaw, Pradhan, Woo Morrey) with CT measurements, same definition plane. retrospectively studied scans in 84 hips patients who underwent primary...
Background Formaldehyde is associated with sick building syndrome (SBS), a set of diffuse and irritative symptoms predominantly involving the eyes respiratory tract. However, its pathophysiological mechanism in SBS has not yet been clarified. Objective In this study we investigated effect formaldehyde on expression adhesion molecules human mucosal microvascular endothelial cells (HMMECs). Furthermore, adhesiveness HMMECs to eosinophils. Materials methods were incubated various concentrations...
The development of standards for encoding mathematical models is an important component model building and sharing among scientists interested in understanding multi-scale physiological processes. CellML provides such a standard, particularly based on biophysical mechanisms, substantial number are now available the Model Repository. However, there urgent need to extend current metadata standard provide biological annotation order facilitate sharing, automated reduction connection databases....
It has been considered that the brain stabilizes unstable body dynamics by regulating co-activation levels of antagonist muscles. Here we critically reexamined this established theory impedance control in a postural balancing task using novel EMG-based human-computer interface, which subjects were asked to balance virtual inverted pendulum visual feedback information on pendulum's position. The was actuated pair joint torques determined real-time activations corresponding ankle muscles...
The stabilization of an inverted pendulum on a manually controlled cart (cart-inverted-pendulum; CIP) in upright position, which is analogous to balancing stick fingertip, considered order investigate how the human central nervous system (CNS) stabilizes unstable dynamics due mechanical instability and time delays neural feedback control. We explore possibility that type intermittent time-delayed control, has been proposed for postural control during quiet standing, also promising strategy...
Postural instability is one of the major symptoms Parkinson’s disease. Here, we assimilated a model intermittent delay feedback control during quiet standing into postural sway data from healthy young and elderly individuals as well patients with disease to elucidate possible mechanisms instability. Specifically, estimated joint probability distribution set parameters in using Bayesian parameter inference such that inferred can best-fit for each individual. It was expected values three...
Cervical transcutaneous spinal cord stimulation (tSCS) efficacy for rehabilitation of upper-limb motor function was suggested to depend on recruitment Ia afferents. However, selectivity and excitability activation with different electrode configurations remain unclear. In this study, pools examined cathode anode during cervical tSCS in 10 able-bodied individuals. Muscle responses were measured from six muscles simultaneously. First, postactivation depression confirmed paired pulses (50-ms...
This paper explores a predictive game in which Forecaster announces odds based on time-homogeneous Markov kernel, establishing game-theoretic law of large numbers for the relative frequencies occurrences all finite strings. A key feature our proof is betting strategy built universal coding scheme, inspired by martingale convergence theorem and algorithmic randomness theory, without relying diversified approach that involves countably many operating accounts. We apply these insights to...
Drying experiments were conducted on raw potato slices, using atmospheric pressure superheated steam and hot air as drying media at 170 240°C. Mass changes of the material continuously measured, conditions cross section near surfaces observed with an electron microscope, also color their surface measured during drying. The respective methods temperature compared it was found that, in case drying, moisture content temporarily increases due to condensation initial stage therewith, well starch...
The main purpose of this study is to compare two different feedback controllers for the stabilization quiet standing in humans, taking into account that intrinsic ankle stiffness insufficient and there a large delay inducing instability loop: 1) standard linear, continuous-time PD controller 2) an intermittent characterized by switching function defined phase plane, with or without dead zone around nominal equilibrium state.The stability analysis first carried out using tools linear control...
Abstract Proper spatiotemporal gene expression is achieved by selective DNA binding of transcription factors in the genome. The most intriguing question how dynamic interactions between and their target sites contribute to regulation recruiting basal transcriptional machinery. Here we demonstrate individual dissociation events factor cAMP response element-binding protein (CREB), both vitro living cells, using single-molecule imaging. Fluorescent–tagged CREB bound its sequence cAMP-response...
Background Although interleukin (IL)‐4 and IL‐5 have been demonstrated to play a critical role in the pathophysiology of allergic diseases such as rhinitis, mechanism that causes predominance Th2 lymphocytes has yet be clarified. Thymus activation‐regulated chemokine (TARC) known facilitate recruitment, activation development polarized cells, leading investigators suggest for TARC responses. Objective To gain better understanding pathogenesis rhinitis we investigated cellular sources this...
Abstract A heat and mass transfer model was proposed for the superheated steam drying, focusing on phenomena which occur during initial stage of i.e., condensation material surfaces subsequent shift from to evaporation leading beginning actual drying (Reverse Process Model). Next, equations considering reverse process were formulated a shrinking/swelling infinite flat plate calculate moisture content temperature distributions in material, changes with time, characteristic curve. Then,...
Objective. Cervical transcutaneous spinal cord stimulation (tSCS) is a promising technology that can support motor function recovery of upper-limbs after injury. Its efficacy may depend on the ability to recruit sensory afferents, conveying excitatory inputs onto motoneurons. Therefore, understanding its physiological mechanisms critical accelerate development towards clinical applications. In this study, we used an anatomically realistic cervical tSCS computational model compare α-motor,...