A5103126263- Sleep and related disorders
- Sleep and Wakefulness Research
- Mental Health Research Topics
- Dementia and Cognitive Impairment Research
- Obstructive Sleep Apnea Research
- Digital Mental Health Interventions
- Mental Health Treatment and Access
- Sleep and Work-Related Fatigue
- COVID-19 and Mental Health
- Parkinson's Disease Mechanisms and Treatments
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Dysphagia Assessment and Management
- Workplace Health and Well-being
- Emotion and Mood Recognition
- Employment and Welfare Studies
- Restless Legs Syndrome Research
- Heart Rate Variability and Autonomic Control
- Temporomandibular Joint Disorders
- Alzheimer's disease research and treatments
- Social Robot Interaction and HRI
- Tryptophan and brain disorders
- EEG and Brain-Computer Interfaces
- Stress Responses and Cortisol
- Neurological Disease Mechanisms and Treatments
- IoT-based Smart Home Systems
Osaka University
2014-2024
Osaka Health Science University
2007-2023
Osaka University Hospital
2010-2022
Saitama Medical University
2022
Kyoto University
2022
University of Occupational and Environmental Health Japan
2022
Counseling Center
2019-2020
Itami City Hospital
2019-2020
Ethics and Public Policy Center
2019-2020
Ehime University
2007-2013
Abstract Neurofilament light chain (NfL) is a novel biomarker of neurodegenerative diseases. It detectable in the peripheral blood, allowing low-invasive assessment early signs neurodegeneration. The level NfL gradually increases with age; however, what other factors affect it remains unclear. present study examined association between blood and renal function among healthy participants undergoing health check (n = 43, serum NfL) patients diabetes mellitus 188, plasma NfL). All were 60 years...
Despite many studies about the association between caregiver burden and behavioral psychological symptoms of dementia (BPSD), there have been no population-based to evaluate associated with each BPSD.To individual BPSD in elderly people living community.The subjects were 67 participants their caregivers (diagnosed third Nakayama study): 51 Alzheimer's disease, 5 vascular 11 other. The Neuropsychiatric Inventory (NPI) NPI Caregiver Distress Scale (NPI-D) used assess subjects' related...
Behavioral and psychological symptoms of dementia (BPSDs) negatively impact the prognosis patients increase caregiver distress. The aims this study were to clarify differences trajectories 12 kinds BPSDs by disease severity in four major dementias develop charts showing frequency, severity, associated distress (ACD) using data a Japan multicenter (J-BIRD).We gathered Neuropsychiatric Inventory (NPI) with Alzheimer's (AD; n = 1091), Lewy bodies (DLB; 249), vascular (VaD; 156), frontotemporal...
This paper proposes a new approach to automatically detect dementia. Even though some works have detected dementia from speech and language attributes, most applied detection using picture descriptions, narratives, cognitive tasks. In this paper, we propose computer avatar with spoken dialog functionalities that produces queries based on the mini-mental state examination, Wechsler memory scale-revised, other related neuropsychological questions. We recorded interactive data of dialogues 29...
Twenty-one dogs were studied under conditions of normal oxygenation and hypoxia with the microsphere distribution method to determine effect arterial oxygen saturation on regional cardiac output. The anesthetized artifically ventilated. Cannulas placed in left ventricle administer microspheres a peripheral artery Each dog received two injections: (1) while normally oxygenated (room air), (2) (10% oxygen-90% nitrogen 10 5% oxygen-95% 11 dogs). Absolute output increased from 87 +/- 15 ml/min...
Abstract Background When comparing with early‐onset Alzheimer's disease (EO‐AD) and late‐onset (LO‐AD), some symptomatological differences in clinical features can be seen between them. Rapid progression, more severe language problems or visuospatial dysfunction occur often EO‐AD patients. However, there have been very few reports about the behavioral psychological symptoms these two groups. Aim The aim of this study was to demonstrate LO‐AD Method Three hundred seven consecutive outpatients...
Background: Eating problems occur frequently in patients with dementia, and almost half of all Parkinson's disease have such problems. It has therefore been assumed that eating are also common dementia Lewy bodies (DLB). However, few systematic studies investigated DLB patients. The aim this study was to clarify the frequency characteristics DLB.Methods: We examined 29 consecutive 33 Alzheimer's (AD) terms age, sex, education, Mini-mental State Examination, clinical rating (CDR),...
Background Sleep disturbances in Alzheimer disease (AD) may affect behavioral and psychological symptoms of dementia (BPSD). Our aim was to elucidate the associations between sleep other BPSD at different stages AD. Methods This investigation part a multicenter‐retrospective study Japan (J‐BIRD). Eligible for final analyses were 684 AD patients. Global severity estimated using Clinical Dementia Rating (CDR) scale. assessed Neuropsychiatric Inventory (NPI). We analyzed relationships according...
Cognitive restructuring is a well-established mental health technique for amending automatic thoughts, which are distorted and biased beliefs about situation, into objective balanced thoughts. Since virtual agents can be used anytime anywhere, they expected to perform cognitive without being influenced by medical infrastructure or patients' stigma toward illness. Unfortunately, since the quantitative analysis of human-agent interaction still insufficient, effect on user's state remains...
Abstract Obesity is a common predisposition to gastroesophageal reflux disease (GERD) and obstructive sleep apnea syndrome (OSAS). By statistical analysis of the respondents questionnaire that was distributed members Kansai Rugby Association, we examined whether weight gain increased incidence these diseases GERD alone disturbs sleep. Prevalence distribution by age differed from another survey, which suggests predispositions other than may contribute GERD. Weight tended increase In our...
Aims: Oxidative stress has gained attention recently in psychiatric medicine and been reported to be associated with various diseases. However, the psychosocial factors involved oxidative are still not well understood. Thus, aim of this study was examine whether anxiety levels neuroticism were serum anti‐oxidative status healthy college students. Methods: Participants cross‐sectional 54 non‐smoking Their determined by reactive oxygen metabolites (ROM) biological anti‐oxidant potential....
To investigate the objective and subjective characteristics of sleep psychosomatic physiologic variables in young subjects with different frequencies rhythmic masticatory muscle activity (RMMA) during sleep.A total 54 (mean age 23.8 ± 2.1 years), healthy underwent polysomnographic (PSG) recordings for 2 nights. Sleep states were assessed prior to PSG using validated questionnaires, following before after sleep: quality, physical symptoms, anxiety level, salivary biomarkers. Second-night...
The Japanese Psycho-Oncology Society and Association of Supportive Care in Cancer recently launched the clinical practice guidelines for delirium adult cancer patients. aim was to provide evidence-based recommendations assessment management This article reports process developing guideline summarizes made.The were developed accordance with Medical Information Network Distribution Service creation procedures. development group, consisting multidisciplinary members, formulated nine questions....
This paper proposes a new approach to detecting very early stage of dementia automatically. We develop computer avatar with spoken dialog functionalities that produces natural queries referring Mini Mental State Examination, Wechsler Memory Scale-Revised and other related questions. Multimodal interactive data dialogues from 18 participants (9 dementias 9 healthy controls) are recorded, audiovisual features extracted. confirm the support vector machines can classify into two groups 0.94...