A5065999206- Functional Brain Connectivity Studies
- Advanced Neuroimaging Techniques and Applications
- Transcranial Magnetic Stimulation Studies
- Schizophrenia research and treatment
- Neurological disorders and treatments
- EEG and Brain-Computer Interfaces
- Fetal and Pediatric Neurological Disorders
- Pneumonia and Respiratory Infections
- Intensive Care Unit Cognitive Disorders
- Advanced MRI Techniques and Applications
- Frailty in Older Adults
- Antibiotic Resistance in Bacteria
- Diet and metabolism studies
- Epigenetics and DNA Methylation
- Artificial Intelligence in Healthcare and Education
- Radiomics and Machine Learning in Medical Imaging
- Genetic Associations and Epidemiology
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Bipolar Disorder and Treatment
- Nutrition and Health in Aging
- Birth, Development, and Health
- MRI in cancer diagnosis
- Fatty Acid Research and Health
- Mental Health and Psychiatry
- Hallucinations in medical conditions
Osaka University
2022-2025
Keio University
2025
Wakayama Medical University
2014-2024
Tokyo Metropolitan University
2022-2024
Osaka Metropolitan University
2022-2024
Showa General Hospital
2022-2024
Ludwig-Maximilians-Universität München
2018-2024
LMU Klinikum
2018-2023
Medizinische Hochschule Hannover
2023
Gunma University
2023
Prefrontal cortex (PFC) regions are promising targets for therapeutic applications of non-invasive brain stimulation, e.g. transcranial direct current stimulation (tDCS), which has been proposed as a novel intervention major depressive disorder (MDD) and negative symptoms schizophrenia (SCZ). However, the effects tDCS vary inter-individually, dose–response relationships have not established. Stimulation parameters often tested in healthy subjects transferred to clinical populations. The...
Recent studies have found a relationship between fear of COVID-19 and mental health problems. Medical workers caring for patients tend to suffer from problems; however, the impact their personality traits, in form problems like depression anxiety Japan is unclear. In this study, we investigated risk nurses’ anxiety, predicted by Big Five traits. A total 417 nurses working hospitals providing care Wakayama prefecture Kansai region participated study. The questionnaires comprised items on...
Background The current biomarker-supported diagnosis of Alzheimer’s disease (AD) is hindered by invasiveness and cost issues. This study aimed to address these challenges utilizing portable electroencephalography (EEG). We propose a novel, non-invasive, cost-effective method for identifying AD, using sample patients with biomarker-verified facilitate early accessible screening. Methods included 35 confirmed via cerebrospinal fluid sampling, age- sex-balanced healthy volunteers (HVs). All...
Diagnosing Alzheimer's disease (AD) through pathological markers is typically costly and invasive. This study aims to find a noninvasive, cost-effective method using portable electroencephalography (EEG) detect changes in AD-related biomarkers cerebrospinal fluid (CSF). A total of 102 patients, both with without biomarker (amyloid beta phosphorylated tau), were recorded 2-minute resting-state EEG. machine-learning algorithm then analyzed the EEG data identify these changes. The results...
Integration of a nanobody-nanoluciferase fusion protein into lateral flow immunoassay for sensitive bioluminescence signaling-based aflatoxin B1 detection using digital camera.
BackgroundLittle is known regarding interhemispheric functional connectivity (FC) abnormalities via the corpus callosum in subjects with bipolar disorder (BD), which might be a key pathophysiological basis of emotional processing alterations BD.MethodsWe performed tract-based spatial statistics (TBSS) using diffusion tensor imaging (DTI) 24 healthy control (HC) and 22 BD subjects. Next, we analyzed neural networks independent component analysis (ICA) 32HC 25 resting-state magnetic resonance...
Cognitive impairment is strongly associated with functional outcome in patients schizophrenia but its pathophysiology remains largely unclear. Involvement of omega-3 fatty acids the cognitive function healthy individuals and neuropsychiatric disease has received increasing attention. The aim this study was to examine relationship between function, social psychiatric symptoms schizophrenia. subjects included 30 or schizoaffective disorder. Psychiatric symptoms, were assessed using Positive...
Microfold (M) cells residing in the follicle-associated epithelium of mucosa-associated lymphoid tissues are specialized for sampling luminal antigens to initiate mucosal immune responses. In past decade, glycoprotein 2 (GP2) and Tnfaip2 were identified as reliable markers M Peyer's patches intestine. Furthermore, RANKL–RANK signaling, well canonical non-canonical NFκB pathways downstream, is essential M-cell differentiation from intestinal stem cells. However, molecular characterization...
The dynamics of large-scale networks, which are known as distributed sets functionally synchronized brain regions and include the visual network (VIN), somatomotor (SMN), dorsal attention (DAN), salience (SAN), limbic (LIN), frontoparietal (FPN), default mode (DMN), play important roles in emotional cognitive processes humans. Although disruptions these networks considered critical for pathophysiological mechanisms psychiatric disorders, their role disorders remains unknown. We aimed to...
Abstract Introduction The corpus callosum serves the essential role of relaying cognitive information between homologous regions in left and right hemispheres brain. Cognitive impairment is a core dysfunction schizophrenia, but much its pathophysiology unknown. aim this study was to elucidate association microstructural abnormalities schizophrenia. Methods We examined stepwise multiple regression analysis investigate relationship fractional anisotropy (FA) callosal fibers each segment with z...
The hippocampus is relevant to cognitive function in schizophrenia (SCZ) and mood disorder patients. Although not anatomically uniform, it clearly divided into subfields. This study aimed elucidate the relationship between hippocampal subfield volume patients with SCZ, bipolar (BP), major depressive (MDD).The included 21 22 BP, MDD 25 healthy controls (HCs). Neurocognitive was assessed using Brief Assessment of Cognition Schizophrenia. We obtained volumes FreeSurfer 6.0. compared 4 groups...
Abstract Physical inactivity and cognitive impairment in patients with chronic obstructive pulmonary disease (COPD) can lead to frailty poor prognoses. However, little is known regarding the association between human brain. We hypothesized that brain structure could change according COPD focused on cortical thickness. Cortical thickness measured by magnetic resonance imaging scores using Kihon Checklist (KCL) were assessed 40 stable 20 healthy controls. Among 34 regions assessed, multiple...