Clement Adebamowo
A5008794707- Cervical Cancer and HPV Research
- Global Cancer Incidence and Screening
- Cancer Genomics and Diagnostics
- BRCA gene mutations in cancer
- Cancer Immunotherapy and Biomarkers
- Genetic Associations and Epidemiology
- Immunotherapy and Immune Responses
- Ferroptosis and cancer prognosis
- Nutrition, Genetics, and Disease
- Viral-associated cancers and disorders
- Nutritional Studies and Diet
- Ethics in Clinical Research
- Cancer Risks and Factors
- Genomic variations and chromosomal abnormalities
- Hepatitis B Virus Studies
- Global Public Health Policies and Epidemiology
- Metabolomics and Mass Spectrometry Studies
- Genetics, Bioinformatics, and Biomedical Research
- Reproductive tract infections research
- Colorectal Cancer Screening and Detection
- Gene expression and cancer classification
- Genomics and Rare Diseases
- Genetic factors in colorectal cancer
- Cancer-related molecular mechanisms research
- HIV/AIDS Research and Interventions
U-M Rogel Cancer Center
2016-2025
University of Ibadan
2012-2025
University of Maryland, Baltimore
2016-2025
Institute of Human Virology
2015-2024
University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center
2014-2024
University of Jos
2023-2024
AIDS Prevention Initiative in Nigeria
2024
Howard University
2006-2023
Clinton Health Access Initiative
2023
Prevention Institute
2022
The goal of the International HapMap Project is to determine common patterns DNA sequence variation in human genome and make this information freely available public domain. An international consortium developing a map these across by determining genotypes one million or more variants, their frequencies degree association between them, samples from populations with ancestry parts Africa, Asia Europe. will allow discovery variants that affect disease, facilitate development diagnostic tools,...
We analyzed molecular data on 2,579 tumors from The Cancer Genome Atlas (TCGA) of four gynecological types plus breast. Our aims were to identify shared and unique features, clinically significant subtypes, potential therapeutic targets. found 61 somatic copy-number alterations (SCNAs) 46 significantly mutated genes (SMGs). Eleven SCNAs 11 SMGs had not been identified in previous TCGA studies the individual tumor types. functionally estrogen receptor-regulated long non-coding RNAs (lncRNAs)...
H3Africa is developing capacity for health-related genomics research in Africa
The Breast Health Global Initiative (BHGI) brought together international breast cancer experts to discuss in low resource countries (LRCs) and identify common concerns reviewed this consensus statement. There continues be a lack of public health care professionals' awareness the importance early detection cancer. Mastectomy most treatment for cancer; surgeons anesthesia services was identified as contributing factor delayed surgical therapy LRCs. Where available, radiation is still more...
Hypertension, the leading single cause of morbidity and mortality worldwide, is a growing public health problem in sub-Saharan Africa (SSA). Few studies have estimated compared burden hypertension across different SSA populations. We conducted cross-sectional analysis blood pressure data collected through cohort study four countries, to estimate prevalence pre-hypertension, hypertension, identify factors associated with hypertension. Participants were from five population groups defined by...
Abstract Laboratory and animal studies suggest that dietary flavonols may reduce breast cancer risk but there are limited epidemiological studies. We computed flavonol intakes from data collected by validated food frequency questionnaires in 1991 1995 90,630 women the Nurses Health Study II. Using multivariate relative risks (RR) 95% confidence intervals (95% CI), we evaluated association of intake with who were premenopausal aged between 26 46 years at baseline 1991. During 8 follow‐up,...
There has been a remarkable paucity of evidence for an association between diet and acne. Our previous studies suggest that there is milk intake teenage This prospective cohort study to evaluate relationship. We studied 6,094 girls, aged 9-15 years in 1996, who reported dietary on up three food frequency questionnaires from 1996 1998. Presence severity acne was assessed by questionnaire 1999. computed multivariate prevalence ratios (PR) 95 percent confidence intervals After accounting age at...
Cancer is an increasingly important public health problem in developing countries, including Africa [1]. As and professional awareness of the cancer has grown, so interest pattern disease presentation, its epidemiology treatment outcome. To date, however, there been limited research about breast Africa. In absence systematic population-based registration, most information come from small clinical pathology case series bias inherent these types studies influenced current understanding...
The Policy Forum allows health policy makers around
Objectives To explore the barriers to cervical cancer screening, focusing on religious and cultural factors, in order inform group-specific interventions that may improve uptake of screening programmes. Design We conducted four focus group discussions among Muslim Christian women Nigeria. Setting Discussions were two hospitals, one South West other North Central region Participants 27 22 over age 18, with no diagnosis cancer. Results Most participants had heard about except Western who never...
Overweight and obesity are on the rise in developing countries including sub-Saharan Africa. We undertook a four-country survey to show collective burden of these health conditions as they occur currently Africa determine differences between urban rural populations other socio-economic factors. Participants were nurses two hospitals Nigeria (200), school teachers South (489) Tanzania (229), village residents one peri-urban (297) location Uganda (200) who completed standardised questionnaire....
In this study, we evaluated the association between high-risk human papillomavirus (hrHPV) and vaginal microbiome. Participants were recruited in Nigeria April August 2012. Vaginal bacterial composition was characterized by deep sequencing of barcoded 16S rRNA gene fragments (V4) on Illumina MiSeq HPV identified using Roche Linear Array® genotyping test. We used exact logistic regression models to evaluate community state types (CSTs) microbiota hrHPV infection, weighted UniFrac distances...
Gut dysbiosis has been associated with several disease outcomes including diabetes in human populations. Currently, there are no studies of the gut microbiome composition relation to type 2 (T2D) Africans. Here, we describe profile nondiabetic adults and investigate association between microbiota T2D urban West was determined 291 Nigerians (98 T2D, 193 non-T2D controls) using fecal 16S V4 rRNA gene sequencing done on Illumina MiSeq platform. Data analysis operational taxonomic units (OTU)...