- Genomics and Phylogenetic Studies
- Chromosomal and Genetic Variations
- RNA and protein synthesis mechanisms
- Cancer Genomics and Diagnostics
- Genetic Mapping and Diversity in Plants and Animals
- RNA modifications and cancer
- Machine Learning in Bioinformatics
- Genomic variations and chromosomal abnormalities
- Genomics and Rare Diseases
- Genetic and phenotypic traits in livestock
- RNA regulation and disease
- Plant Molecular Biology Research
- Cancer-related molecular mechanisms research
- Glioma Diagnosis and Treatment
- Genomics and Chromatin Dynamics
- Animal Genetics and Reproduction
- Photosynthetic Processes and Mechanisms
- Lung Cancer Treatments and Mutations
- Ubiquitin and proteasome pathways
- Epigenetics and DNA Methylation
- Plant tissue culture and regeneration
- Lipid metabolism and biosynthesis
Shandong Agricultural University
2025
Wuhan University
2020
Baylor College of Medicine
2004-2011
Baylor Genetics
2011
Texas Biomedical Research Institute
2007
University of Washington
2007
Washington University in St. Louis
2007
A survey of genetic diversity cattle suggests two domestication events in Asia and selection by husbandry.
Atlas is a suite of programs developed for assembly genomes by "combined approach" that uses DNA sequence reads from both BACs and whole-genome shotgun (WGS) libraries. The BAC clones afford advantages localized with reduced computational load, provide robust method dealing repeated sequences. Inclusion WGS sequences facilitates use different clone insert sizes reduces data production costs. A core function software recruitment into appropriate based on overlaps. Because construction...
Abstract Background We present here the assembly of bovine genome. The method combines BAC plus WGS local used for rat and sea urchin with whole genome shotgun (WGS) only many other animal genomes including rhesus macaque. Results process consisted multiple phases: First, BACs were assembled generated sequence, then subsequently in combination individual overlapping reads. Different parameters tested to separately optimize performance each In parallel, a second was produced using sequences...
Campylobacter jejuni (C. jejuni), is a leading cause of food-borne pathogen, poses significant threats to poultry industry and public health. Post-transcriptional modifications play crucial roles in regulating the immune system cell functions. However, epigenetic regulation response C. inoculation chicken remains elusive. The RNA transcriptional profiles base modification alterations cecum following were characterized using direct sequencing analyzed by bio-informatics expression analysis....
Abstract Background Rhesus macaques are the most widely utilized nonhuman primate model in biomedical research. Previous efforts have validated fewer than 900 single nucleotide polymorphisms (SNPs) this species, which limits opportunities for genetic studies related to health and disease. Extensive information about SNPs other variation rhesus would facilitate valuable analyses, as well provide markers genome-wide linkage analysis management of captive breeding colonies. Results We used...
Vegetable oil is a major edible and an important industrial raw material. However, breeders have found it challenging to improve the content of crop seeds, little known about regulators with potential increase via molecular engineering in modern breeding. We reported F-box protein, Arabidopsis thaliana MYB Interaction Factor 1 (AtMIF1), which member ubiquitin-protein ligase E3 complex involved 26S proteasome protein degradation pathway. AtMIF1 physically interacts domain 5 (MYB5), results...