A5071343039- Genetic and phenotypic traits in livestock
- Genetic Mapping and Diversity in Plants and Animals
- Genetic diversity and population structure
- Meat and Animal Product Quality
- Cancer-related molecular mechanisms research
- Animal Genetics and Reproduction
- Animal Nutrition and Physiology
- Identification and Quantification in Food
- Biofuel production and bioconversion
- Bioenergy crop production and management
- Muscle Physiology and Disorders
- Forest Biomass Utilization and Management
- RNA Research and Splicing
- Molecular Biology Techniques and Applications
- Animal Disease Management and Epidemiology
- Genetics and Plant Breeding
- Cardiomyopathy and Myosin Studies
- Genomics and Phylogenetic Studies
- Archaeology and ancient environmental studies
- Adipose Tissue and Metabolism
- Calpain Protease Function and Regulation
- Paleopathology and ancient diseases
- Microbial infections and disease research
- Photoreceptor and optogenetics research
- RNA and protein synthesis mechanisms
Università degli Studi della Tuscia
2013-2023
Azienda Sanitaria Locale Viterbo
2015
Département Santé Animale
2013
University of Milan
2010
University of Wales
2006
Justus-Liebig-Universität Gießen
2006
Utrecht University
2006
Università Cattolica del Sacro Cuore
2006
École Polytechnique Fédérale de Lausanne
2006
Universidad Complutense de Madrid
2006
A survey of genetic diversity cattle suggests two domestication events in Asia and selection by husbandry.
Increased inbreeding is an inevitable consequence of selection in livestock populations. The analysis high-density single nucleotide polymorphisms (SNPs) facilitates the identification long and uninterrupted runs homozygosity (ROH) that can be used to identify chromosomal regions are identical by descent. In this work, distribution ROH different lengths five Italian cattle breeds described. A total 4095 bulls from (2093 Holstein, 749 Brown, 364 Piedmontese, 410 Marchigiana 479 Simmental)...
For about 10 000 years, farmers have been managing cattle, sheep, and goats in a sustainable way, leading to animals that are well adapted the local conditions. About 200 years ago, situation started change dramatically, with rise of concept breed. All from same breed began be selected for phenotypic characteristics, reproduction among breeds was seriously reduced. This corresponded strong fragmentation initial populations. A few decades selection pressures were increased again order further...
Among the European countries, Italy counts largest number of local goat breeds. Thanks to recent availability a medium-density SNP (single nucleotide polymorphism) chip for goat, genetic diversity Italian populations was characterized by genotyping samples from 14 breeds that originate different geographical areas with more than 50 000 SNPs evenly distributed on genome. Analysis data revealed high levels polymorphism and an underlying North–south geographic pattern highlighted both first...
This work reports on use of the recently described amplified fragment length polymorphism (AFLP) technology for DNA fingerprinting in cattle. The AFLP produces molecular markers through high-stringency polymerase chain reaction (PCR)-amplification restriction fragments that are ligated to synthetic adapters and using primers, complementary adapters, which carry selective nucleotides at their 3' ends. While, plants, double digestion genomic with EcoRI MseI is suggested, mammals enzyme...
The domestic water buffalo is native to the Asian continent but through historical migrations and recent importations, nowadays has a worldwide distribution. two types of buffalo, i.e. river swamp, display distinct morphological behavioural traits, different karyotypes also have purposes geographical distributions. River buffaloes from Pakistan, Iran, Turkey, Egypt, Romania, Bulgaria, Italy, Mozambique, Brazil Colombia, swamp China, Thailand, Philippines, Indonesia were genotyped with...
Calving in cattle is affected by calf morphology and dam characteristics. It described two different traits: maternal calving ease, which the ability to generate dams with good physiological predisposition calving, direct calves that are easily born. The aim of this study was identify regions genome harboring genes possibly affecting ease Piedmontese breed. A population 323 bulls scored for (EBV) analyzed a medium-density SNP marker panel (54,001 SNPs) perform genome-wide scan. strongest...
Abstract Water buffalo is a globally important species for agriculture and local economies. A de novo assembled, well-annotated reference sequence the water an prerequisite studying biology of this species, necessary to manage genetic diversity use modern breeding genomic selection techniques. However, no such genome assembly has been previously reported. There are 2 domestic buffalo, river (2n = 50) swamp 48) buffalo. Here we describe draft quality created from Illumina GA Roche 454 short...
Consumer complaints against the blandness of modern lean meat and frequent reference to more strongly flavored that was available years ago have prompted reconsideration high fat-depositing typical pig breeds. Casertana Large White breeds are characterized by a different tendency toward fat accumulation as they exhibit opposite genetic physiological traits with respect energy metabolism. These differences were investigated in longissimus lumborum muscles through proteomics (2-DE, MS/MS)...
In this study we compare outlier loci detected using a F ST based method with those identified by recently described on spatial analysis (SAM). We tested panel of single nucleotide polymorphisms (SNPs) previously genotyped in individuals goat breeds southern areas the Mediterranean basin (Italy, Greece and Albania). evaluate how SAM performs SNPs, which are increasingly employed due to their high number, low cost easy scoring. The combined use two detection approaches, never before SNP...
Copy number variations (CNVs) represent a significant source of genomic structural variation. Their length ranges from approximately one hundred to millions base pair. Genome-wide screenings have clarified that CNVs are ubiquitous phenomenon affecting essentially the whole genome. Although Bos taurus is most important domestic animal species worldwide and studied ruminant models for metabolism, reproduction, disease, relatively few studies investigated in cattle little known about how...
Arundo donax has attracted renewed interest as a potential candidate energy crop for use in biomass-to-liquid fuel conversion processes and biorefineries. This is due to its high productivity, adaptability marginal land conditions, suitability biofuel biomaterial production. Despite importance, the genomic resources currently available supporting improvement of this species are still limited. We used RNA sequencing (RNA-Seq) de novo assemble characterize A. leaf transcriptome. The generated...
Our objectives for this study were to understand the biological basis of meat tenderness and provide an overview gene expression profiles related quality as a tool selection. Through deep mRNA sequencing, we analyzed in muscle tissues two Italian cattle breeds: Maremmana Chianina. We uncovered several differentially expressed genes that encode proteins belonging family tripartite motif proteins, which are involved growth, cell differentiation apoptosis, such TRIM45, or play essential role...
Amplified fragment length polymorphism (AFLP) markers were used to investigate the genetic variation in a sample of seven goat (Capra hircus) populations. A total 210 individuals (30 per population) analysed using selected AFLP primer combinations that produced 219 clear polymorphisms. Four autochthonous breeds (Bionda dell'Adamello, Frisa, Orobica and Verzaschese), two primary populations, one from Lombardy Alps (Val di Livo) other Sardinia island (Sarda) reference cosmopolitan breed...
We herein describe a procedure that allows for simultaneous genotyping of six loss‐of‐function mutations in the bovine myostatin gene associated with double‐muscling phenotype. The proposed method relies on multiplex oligonucleotide ligation assay and detection fluorescently labelled products using automatic sequencers.
Summary The Neolithic introduction of domestic cattle into Europe was followed by differential adaptation, selection, migration and genetic isolation, leading ultimately to the emergence specialized breeds. We have studied differentiation European amplified fragment length polymorphism (AFLP) fingerprinting. Combining AFLP data sets from two laboratories yielded 81 biallelic polymorphic markers scored in 19–22 individual animals 51 Model‐based clustering differentiated Podolian as well...
Domestication and selection are processes that alter the pattern of within- between-population genetic variability. They can be investigated at genomic level by tracing so-called signatures. Recently, sequence polymorphisms genome-wide have been in a wide range animals. A common approach to detect signatures is compare breeds selected for different breeding goals (i.e. dairy beef cattle). However, variations with similar production aptitudes phenotypes related differences their history. In...
A number of methods are available to scan a genome for selection signatures by evaluating patterns diversity within and between breeds. Among these, "extended haplotype homozygosity" (EHH) is reliable approach detect regions under recent selective pressure. The objective this study was use identify that positive shared the most representative Italian dairy beef cattle total 3220 animals from Holstein (2179), Brown (775), Simmental (493), Marchigiana (485) Piedmontese (379) breeds were...
Summary A set of 11 polymorphic microsatellites has been used to assess the distribution genetic variability in 17 flocks Sarda sheep breed Viterbo province, located central Italy. The suitability samples size and number loci analysed were tested using a bootstrap procedure. data obtained estimate diversity within among flocks, test presence inbreeding flocks. To study relationship principal component analysis based on Nei standard distances was performed. results show significant excess...
Summary Eighteen microsatellites were used to investigate the genetic diversity and differentiation of eight Chinese indigenous goat breeds. The results indicated that there is a significant difference between different loci. breeds have similar other Asian goats, but with lower Fst . clustering individuals populations showed might originated from two ancestral populations. consistent archaeology, mtDNA RAPD.