G.R. Wiggans

ORCID: 0000-0002-3604-6639
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Genetic and phenotypic traits in livestock
  • Genetic Mapping and Diversity in Plants and Animals
  • Reproductive Physiology in Livestock
  • Genetics and Plant Breeding
  • Effects of Environmental Stressors on Livestock
  • Milk Quality and Mastitis in Dairy Cows
  • Animal Behavior and Welfare Studies
  • Animal Nutrition and Physiology
  • Ruminant Nutrition and Digestive Physiology
  • Cancer-related molecular mechanisms research
  • Animal Genetics and Reproduction
  • Livestock Management and Performance Improvement
  • Wheat and Barley Genetics and Pathology
  • Gene expression and cancer classification
  • Economics of Agriculture and Food Markets
  • Agricultural Economics and Policy
  • Molecular Biology Techniques and Applications
  • Meat and Animal Product Quality
  • Animal Disease Management and Epidemiology
  • Livestock Farming and Management
  • Genomic variations and chromosomal abnormalities
  • Advanced Statistical Methods and Models
  • Genomics and Chromatin Dynamics
  • Optimal Experimental Design Methods
  • Microbial infections and disease research

Dairy Management
2019-2024

JDSU (United States)
2023

Agricultural Research Service
2012-2022

Beltsville Agricultural Research Center
2010-2022

United States Department of Agriculture
1990-2016

Improvement Service
1997-2003

Gembloux Agro-Bio Tech
1998-2001

Aristotle University of Thessaloniki
2001

École Nationale d'Agriculture de Meknès
1999

Fund for Scientific Research
1999

Significance The introduction of genomic selection in dairy cattle improvement programs 2008 was expected to increase rates genetic gain, particularly for traits with low heritabilities, such as fertility and longevity. Our analysis the US national database found that generation intervals have decreased dramatically over past 6 y, intensity lowly heritable has increased considerably. Genetic trends rapidly fertility, lifespan, udder health. These results clearly demonstrate positive impact...

10.1073/pnas.1519061113 article EN Proceedings of the National Academy of Sciences 2016-06-27

Genome-wide association analysis is a powerful tool for annotating phenotypic effects on the genome and knowledge of genes chromosomal regions associated with dairy phenotypes useful gene-based selection. Here, we report results genome-wide predicted transmitting ability (PTA) 31 production, health, reproduction body conformation traits in contemporary Holstein cows.Genome-wide identified number candidate chromosome U.S. cows. Highly significant include: BTA13's GNAS region milk, fat protein...

10.1186/1471-2164-12-408 article EN cc-by BMC Genomics 2011-08-11

10.3168/jds.s0022-0302(91)78453-1 article EN publisher-specific-oa Journal of Dairy Science 1991-08-01

Genomic evaluations in Holstein dairy cattle have quickly become more reliable over the last two years many countries as animals been genotyped for 50,000 markers. Evaluations can also include with or fewer markers using new tools such 777,000 2,900 marker chips recently introduced cattle. Gains from be predicted simulation, whereas strategies to use compared subsets of actual genotypes. The overall cost selection is reduced by genotyping most at less than highest density and imputing their...

10.1186/1297-9686-43-10 article EN cc-by Genetics Selection Evolution 2011-03-02

Meiotic recombination is an essential biological process that generates genetic diversity and ensures proper segregation of chromosomes during meiosis. From a large USDA dairy cattle pedigree with over half million genotyped animals, we extracted 186,927 three-generation families, identified 8.5 maternal paternal events, constructed sex-specific maps for 59,309 autosomal SNPs. The map spans 25.5 Morgans in males 23.2 females, total studied region 2,516 Mb (986 kb/cM 1,085 females). male 10%...

10.1371/journal.pgen.1005387 article EN public-domain PLoS Genetics 2015-11-05

10.3168/jds.s0022-0302(87)80337-5 article EN publisher-specific-oa Journal of Dairy Science 1987-12-01

10.3168/jds.2010-3866 article EN publisher-specific-oa Journal of Dairy Science 2011-05-25

A genome scan was conducted in the North American Holstein-Friesian population for quantitative trait loci (QTL) affecting production and health traits using granddaughter design. Resource families consisted of 1,068 sons eight elite sires. Genome coverage estimated to be 2,551 cM (85%) 174 genotyped markers. Each marker tested effects on milk yield, fat protein percentage, somatic cell score, productive herd life analysis variance. Joint all identified 11 chromosomes that exceeded...

10.1152/physiolgenomics.1999.1.3.165 article EN Physiological Genomics 1999-11-11

The intensive selection programs for milk made possible by mass artificial insemination increased the similarity among genomes of North American (NA) Holsteins tremendously since 1960s. This migration elite alleles has caused certain regions genome to have runs homozygosity (ROH) occasionally spanning millions continuous base pairs at a specific locus. In this study, signatures in NA born between 1953 and 2008 were identified comparing changes ROH three distinct groups under different...

10.1371/journal.pone.0080813 article EN public-domain PLoS ONE 2013-11-14

The Illumina BovineLD BeadChip was designed to support imputation higher density genotypes in dairy and beef breeds by including single-nucleotide polymorphisms (SNPs) that had a high minor allele frequency as well uniform spacing across the genome except at ends of chromosome where densities were increased. chip also includes SNPs on Y mitochondrial DNA loci are useful for determining subspecies classification certain paternal maternal breed lineages. total number 6,909. Accuracy...

10.1371/journal.pone.0034130 article EN cc-by PLoS ONE 2012-03-28

1. Digesta passage and retention were measured in heifers, sheep, goats, equines rabbits of varying body-weights when given timothy ( Phleum pratense ) hay. 2. Two markers compared, cobalt (III) ethylene diamine tetraacetate (CoEDTA) chromiummordanted fibre for liquid solid phase respectively. Both injected into the rumen ruminants caecum andrabbits. 3. In ruminants, two different sets rate constants k 1 2 derived from a two-pool model marker passage, using graphical approach computer-based...

10.1079/bjn19820117 article EN British Journal Of Nutrition 1982-09-01

Genomic selection increases accuracy and decreases generation interval, accelerating genetic changes in populations. Assumptions of improvement must be addressed to quantify the magnitude direction change. Genetic trends US dairy cattle breeds were examined determine gain since implementation genomic evaluations 2009. Inbreeding levels intervals also investigated. Breeds included Ayrshire, Brown Swiss, Guernsey, Holstein (HO), Jersey (JE), which characterized by evaluation breed animal...

10.3168/jds.2022-22205 article EN cc-by Journal of Dairy Science 2022-12-07

10.3168/jds.s0022-0302(91)78631-1 article EN publisher-specific-oa Journal of Dairy Science 1991-12-01

10.3168/jds.s0022-0302(06)72541-3 article EN publisher-specific-oa Journal of Dairy Science 2006-12-01

Abstract Background Btau_4.0 and UMD3.1 are two distinct cattle reference genome assemblies. In our previous study using the low density BovineSNP50 array, we reported a copy number variation (CNV) analysis on with 521 animals of 21 breeds, yielding 682 CNV regions total length 139.8 megabases. Results this high BovineHD SNP performed resolution analyses both 674 27 breeds. We first compared results derived from these different array platforms Btau_4.0. With thirds shared between studies,...

10.1186/1471-2164-13-376 article EN cc-by BMC Genomics 2012-08-06
Coming Soon ...