A5041076253- Adipose Tissue and Metabolism
- Rabbits: Nutrition, Reproduction, Health
- Cancer-related molecular mechanisms research
- Genetic and phenotypic traits in livestock
- MicroRNA in disease regulation
- Animal Nutrition and Physiology
- Genetic Mapping and Diversity in Plants and Animals
- RNA Research and Splicing
- Diet and metabolism studies
- Adipokines, Inflammation, and Metabolic Diseases
- Ruminant Nutrition and Digestive Physiology
- Effects of Environmental Stressors on Livestock
- Reproductive Physiology in Livestock
- Circular RNAs in diseases
- Dermatological diseases and infestations
- Pharmacological Effects of Natural Compounds
- Meat and Animal Product Quality
- RNA modifications and cancer
- Gut microbiota and health
- Genetic diversity and population structure
- High Altitude and Hypoxia
- Peroxisome Proliferator-Activated Receptors
- Lipid metabolism and biosynthesis
- Molecular Biology Techniques and Applications
- Muscle metabolism and nutrition
Sichuan Agricultural University
2016-2025
Ministry of Agriculture and Rural Affairs
2023-2025
University of Florida
2021
Shandong Academy of Agricultural Sciences
2009
The domestic water buffalo is native to the Asian continent but through historical migrations and recent importations, nowadays has a worldwide distribution. two types of buffalo, i.e. river swamp, display distinct morphological behavioural traits, different karyotypes also have purposes geographical distributions. River buffaloes from Pakistan, Iran, Turkey, Egypt, Romania, Bulgaria, Italy, Mozambique, Brazil Colombia, swamp China, Thailand, Philippines, Indonesia were genotyped with...
Abstract Background The greatest impact on profitability of a commercial beef operation is reproduction. However, in heifers, little known about the vaginal and fecal microbiota with respect to their relationship fertility. To this end, we followed heifers through gestation examine dynamics microbial composition throughout pregnancy. Results Heifers were exposed an estrus synchronization protocol, observed over 12-day period, artificially inseminated 12 h 18 after estrus, subsequently bulls...
Abstract Background Sarcoptic mange caused by the mite Sarcoptes scabiei is a worldwide disease affecting both humans and animals. Here we report molecular characterization evaluation of recombinant S. tropomyosin (SsTm) protein in vaccination trial rabbits. Methods The full-length cDNA was cloned bacterial pET vector, expressed BL21 (DE3) cells purified. Using specific rabbit antiserum, localized immunohistochemically tissue sections. Vaccination trials with recombiant SsTm carried out New...
The objective of this study was to compare carcass composition and meat quality traits in the longissimus dorsi biceps femoris muscles Hyla, Champagne Tianfu Black rabbit breeds. rabbits had heaviest head, skin, thoracic viscera commercial percentage (p<0.05). In addition, highest pH0 h value, followed by Hyla breeds (p<0.01) muscles. a higher a* (0 24 h) than other two both Champagne, showed similar pattern differences for (pH, L*, b*) measured fresh stored h. IMF values three (p<0.01)....
Ketosis is a common metabolic disease in dairy cows during early lactation. However, information about the metabolomic and proteomic profiles associated with incidence progression of ketosis still limited. In this study, an integrated metabolomics proteomics approach was performed on blood serum sampled from diagnosed clinical (case, ≥ 2.60 mmol/L plasma β-hydroxybutyrate; BHBA) healthy controls (control, < 1.0 BHBA). Samples were taken 2 weeks before parturition after 19 animals (nine...
Heat stress can impair the rabbit immune system, induce oxidative stress, and cause many complications. These diseases are characterized by metabolic disorders, but underlying mechanism is unknown. As a result, current research determines effects of HS on intestinal microorganisms in rabbits pathway disorders caused HS. Twelve were randomly assigned to one two groups: CON (22-24°C) (30°C-32°C). Both groups treated for 15 days. Blood fecal samples collected day 15. Serum oxidation indices...
Rabbits are an attractive meat livestock species that can efficiently convert human-indigestible plant biomass, and have been commonly used in biological medical researches. Yet, transcriptomic landscape muscle tissue association between gene expression level growth traits not specially studied rabbits. In this study Oxford Nanopore Technologies (ONT) long-read sequencing technology was for comprehensively exploring Longissimus dorsi 115 rabbits at 84 days of age, transcriptome-wide studies...
In recent years, rising temperatures have caused heat stress (HS), which has had a significant impact on livestock production and growth, presenting considerable challenges to the agricultural industry. Research shown that miR-425-5p regulates cellular proliferation in organisms. However, specific role of bovine mammary epithelial cells (BMECs) remains be determined. The aim this study was investigate potential alleviating HS-induced stagnation BMECs. results showed expression significantly...
Simmental cattle are renowned for their dual purpose as meat and dairy breeds. The study recorded phenotype data from 183 performed a Genome-Wide Association Study (GWAS) analysis to elucidate the genetic mechanisms underlying milk production, body size traits, tail characteristics. Statistical of showed that season, parity, age at first calving (AFC) factors had significant effect on production (P < 0.05). results GWAS linear traits revealed candidate genes SH3RF2, DCHS2, ADAMTS1, CAMK4,...
In livestock production, deeply understanding the molecular mechanisms of growth and metabolic differences in different breeds cattle is great significance for optimizing breeding strategies, improving meat quality, promoting sustainable development. This study aims to comprehensively reveal molecular-level between Chinese domestic Simmental crossbred through multi-omics analysis, further provide a theoretical basis efficient development beef industry. The China are unique genetic breed...
Heat stress, exacerbated by global warming, has emerged as a significant concern for both the health of dairy cattle and quality milk production. In vitro investigations suggest that primary bovine mammary epithelial cells exhibit enhanced levels programmed cell death when subjected to elevated ambient temperatures, potentially resulting in reduction total number within gland, thereby partially elucidating diminished yield lactating cows under heat stress. vivo, stress affects synthesis...
miR-211-5p exhibits dysregulated expression in various malignant tumors and has been implicated the regulation of tumor cell proliferation, apoptosis, inflammation, neurogenic processes. Previous studies have demonstrated that miR-211 negatively regulates ELOVL6, suggesting its involvement lipid metabolism lipogenesis within bovine adipose tissue. Our prior transcriptomic analysis revealed upregulated rabbits fed a high-fat diet, indicating potential role regulation. However, precise...
Abstract Background MicroRNAs (miRNAs) are a class of small non-coding RNAs, which participate in the regulation cell differentiation. Previous studies have demonstrated that miR-9-5p plays key role cancer development, but mechanisms by regulates adipogenesis remain poorly understood. The present study intended to investigate its significance producing rabbits with high-quality meat observing regulatory effect preadipocytes and finding related targets. Methods In this study, dual-luciferase...
Growth, carcass characteristics and meat quality are the most important traits used in rabbit industry. Identification of candidate markers genes significantly associated with these will be beneficial breeding. In this study, we enrolled 465 rabbits, including 16 male Californian rabbits 17 female Kangda5 line as parental generation, along their offspring (232 200 female), a genome-wide association study (GWAS) based on SLAF-seq technology. Bodyweight at 35, 42, 49, 56, 63 70 d was recorded...
Pigmentation genes such as MC1R, MITF, TYR, TYRP1, and MLPH play a major role in rabbit coat color. To understand the genotypic profile underlying color indigenous Chinese breeds, portions of above-mentioned were amplified variations them analyzed by DNA sequencing. Based on analysis 24 Tianfu black rabbits, Sichuan white gray Fujian yellow two indels three SNPs five (single nucleotide polymorphisms) one SNP discovered. These have low-to-moderate polymorphism, there are significant...
Heat stress can have an impact on parental gamete maturation and reproduction functions. According to current research, the microbial composition of vaginal cavity is species specific. Pregnancy, menstruation, genital diseases been linked dynamics ecology. In this study, we characterized microbiota metabolites after heat stress. At phylum level, rabbit's rabbit showed high similarity with that humans. group, relative abundance dominant Actinobacteria, Bacteroidetes, Proteobacteria increased,...