A5036326492- Global Cancer Incidence and Screening
- Colorectal Cancer Screening and Detection
- Breast Lesions and Carcinomas
- Breast Cancer Treatment Studies
- AI in cancer detection
- Digital Radiography and Breast Imaging
- Cervical Cancer and HPV Research
- MRI in cancer diagnosis
- Radiation Dose and Imaging
- BRCA gene mutations in cancer
- Medical Imaging Techniques and Applications
- Climate Change and Health Impacts
- Radiology practices and education
- Radiomics and Machine Learning in Medical Imaging
- Cellular transport and secretion
- Global Health and Surgery
- Advances in Oncology and Radiotherapy
- Healthcare cost, quality, practices
- Breast Implant and Reconstruction
- Advanced MRI Techniques and Applications
- Advanced Neuroimaging Techniques and Applications
- Cancer Risks and Factors
- Cancer and Skin Lesions
- Pleural and Pulmonary Diseases
- Lipid Membrane Structure and Behavior
Vanderbilt University Medical Center
2022-2025
Medical Care Development International
2020-2024
Planetary Science Institute
2023-2024
The University of Texas MD Anderson Cancer Center
2024
Women's Health Initiative
2022-2024
Philips (Netherlands)
2024
University of Washington
2014-2023
Cancer Research Center
2016-2023
Fred Hutch Cancer Center
2016-2023
Associated Radiologists
2023
When breast cancer is detected and treated early, the chances of survival are very high. However, women in many settings face complex barriers to early detection, including social, economic, geographic, other interrelated factors, which can limit their access timely, affordable, effective health care services. Previously, Breast Health Global Initiative (BHGI) developed resource‐stratified guidelines for detection diagnosis cancer. In this consensus article from sixth BHGI Summit held...
Purpose To investigate whether qualitative magnetic resonance (MR) imaging assessments of background parenchymal enhancement (BPE), amount fibroglandular tissue (FGT), and mammographic density are associated with risk developing breast cancer in women who at high risk. Materials Methods In this institutional review board–approved HIPAA-compliant retrospective study, all screening MR images obtained from January 2006 to December 2011 aged 18 years or older for but without a history were...
Hypoxia-inducible factor-1α (HIF-1α) plays an essential role in cellular and systemic O 2 homeostasis by regulating the expression of genes important glycolysis, erythropoiesis, angiogenesis, catecholamine metabolism. It is also believed to be a key component response hypoxia ischemia under pathophysiological conditions, such as stroke. To clarify function HIF-1α brain, we exposed adult mice with late-stage brain deletion hypoxic injuries. Contrary expectations, brains from HIF-1 α-deficient...
Abstract Platforms that allow parallel, quantitative analysis of single cells will be integral to realizing the potential postgenomic biology. In stem cell biology, study clonal in multiwell formats is currently both inefficient and time‐consuming. Thus, investigate low‐frequency events interest, large sample sizes must interrogated. We report a simple, versatile, efficient micropatterned arraying system conducive culture dynamic monitoring proliferation. This platform enables: 1) automated,...
The purpose of this study was to describe trends over time in female authorship the radiology literature and investigate tendency first authors publish with senior authors.Data on gender academic physician based United States for all major articles published three general journals--Radiology, AJR, Academic Radiology--were collected analyzed years 1978, 1988, 1998, 2008, 2013. Multivariate logistic regression used identify significant time, a chi-square test independence performed determine...
The objective of our study was to determine the accuracy preoperative measurements for detecting pathologic complete response (CR) and assessing residual disease after neoadjuvant chemotherapy (NACT) in patients with locally advanced breast cancer. American College Radiology Imaging Network 6657 Trial prospectively enrolled women ≥ 3 cm invasive cancer receiving NACT. Preoperative included longest diameter by mammography, MRI, clinical examination functional volume on MRI. CR association...
Performance of DWI as a Rapid Unenhanced Technique for Detecting Mammographically Occult Breast Cancer in Elevated-Risk Women With Dense BreastsElizabeth S. McDonald1,2, Jill A. Hammersley1, Shinn-Huey Chou1, Habib Rahbar1, John R. Scheel1, Christoph I. Lee1, Cheng-Liang Liu1, Constance D. Lehman1 and Savannah C. Partridge1Audio Available | Share
Since the introduction of MRI as a sustainable diagnostic modality, global accessibility to its services has revealed wide discrepancy between populations-leaving most population in LMICs without access this important imaging modality. Several factors lead scarcity LMICs; for example, inadequate infrastructure and absence dedicated workforce are key observed. RAD-AID contributed advancement radiology globally by collaborating with our partners make more accessible medically underserved...
Background Contrast-enhanced mammography (CEM) and abbreviated breast MRI (ABMRI) are emerging alternatives to standard for supplemental cancer screening. Purpose To compare the diagnostic performance of CEM, ABMRI, MRI. Materials Methods This single-institution, prospective, blinded reader study included female participants referred from January 2018 June 2021. CEM was performed within 14 days MRI; ABMRI produced images. Two readers independently interpreted each after a washout period....
A life cycle assessment of a diagnostic radiology department’s environmental footprint identified the energy consumption from imaging equipment as more than 50% its greenhouse gas emissions, well opportunities to improve sustainability.
The advent of the genome facilitated by advances in micro- and nanotechnology has revolutionized our understanding living systems. DNA microarrays, catalytic RNA arrays, protein arrays are all a consequence innovations engineering at nanoscales. Here, we extend this paradigm to fabrication live mammalian cell that can be used investigate state level an integrated system. Specifically, describe electro-optical system utilizes physical properties cells (charge, dielectric permittivity) rather...
The purification, cloning, and complete cDNA-derived sequence of a 17-kDa protein Dictyostelium discoideum are described.This binds to F-actin in pH-dependent saturable manner.It induces actin polymerization the absence Mg2+ or K+, is enriched submembranous region amoeboid cells as indicated by immunofluorescence labeling cryosections.The mRNA well present throughout growth all stages development.The detected both soluble particulate fractions cells.From plasma membrane-enriched fraction,...
Background Greater than 80% of women presenting for breast cancer treatment in Uganda have late‐stage disease, which is attributable to a dysfunctional referral system and lack recognition the early signs symptoms among primary health care providers, compounded by poor infrastructure inadequate human capacity. Improving requires systemic approach beginning with situational analysis identify systematic gaps that prevent sustainable improvements outcome. Methods The authors performed using...
We have established an in vitro assay to characterize the binding of endocytic carrier vesicles microtubules.Magnetic beads coated with microtubules were used as affinity matrix.A fraction from nocodazoletreated cells enriched vesicles, labeled internalized horseradish peroxidase, was experiments.Binding cytosol-dependent.This activity cytosolic factors saturable, heat-sensitive, and insensitive N-ethylmaleimide.Binding sensitive GTP ATP.Addition neuronal microtubule-associated proteins...