- Global Cancer Incidence and Screening
- AI in cancer detection
- Digital Radiography and Breast Imaging
- Breast Cancer Treatment Studies
- Radiomics and Machine Learning in Medical Imaging
- BRCA gene mutations in cancer
- Cancer Risks and Factors
- Artificial Intelligence in Healthcare
- COVID-19 and healthcare impacts
- Colorectal Cancer Screening and Detection
- Breast Lesions and Carcinomas
- Economic and Financial Impacts of Cancer
- MRI in cancer diagnosis
- Artificial Intelligence in Healthcare and Education
- Radiation Dose and Imaging
- Childhood Cancer Survivors' Quality of Life
- Chinese history and philosophy
- Ovarian cancer diagnosis and treatment
- Cancer Genomics and Diagnostics
- Medical Imaging Techniques and Applications
- Hormonal and reproductive studies
- Endometrial and Cervical Cancer Treatments
- Diversity and Career in Medicine
- Advances in Oncology and Radiotherapy
- Soft tissue tumors and treatment
University of Washington
2017-2025
Fred Hutch Cancer Center
2023-2025
The University of Texas at Austin
2025
Dell Children's Medical Center of Central Texas
2025
Seattle Cancer Care Alliance
2017-2024
Screen
2024
Dartmouth College
2021
University of Vermont
2021
Massachusetts General Hospital
2011-2020
Harvard University
2011-2012
Breast cancer screening examinations using digital breast tomosynthesis (DBT) has been shown to be associated with decreased false-positive test results and increased detection compared mammography (DM). Little is known regarding the size stage of types detected their association age density.To determine whether DBT detect cancers that are an improved prognosis compare rates by patient density.This retrospective analysis prospective cohort data from 3 research centers in Population-based...
The coronavirus disease 2019 (COVID-19) pandemic has disrupted breast cancer control through short-term declines in screening and delays diagnosis treatments. We projected the impact of COVID-19 on future mortality between 2020 2030.Three established Cancer Intervention Surveillance Modeling Network models modeled reductions mammography use, symptomatic diagnosis, reduced use chemotherapy for women with early-stage first 6 months return to prepandemic patterns after that time. Sensitivity...
The effects of breast cancer incidence changes and advances in screening treatment on outcomes different strategies are not well known.
BACKGROUND Hypertension is poorly controlled in the US due to medication nonadherence. Recent evidence suggests that nonadherence can be classified as intentional or unintentional and different patient characteristics, such experience of adverse effects, may associated with each. OBJECTIVE To examine associations between including reported both among 588 hypertensive patients. METHODS Baseline data from a clinical trial, Veterans' Study Improve Control Hypertension, were examined....
Abstract BACKGROUND: Although breast cancer screening with mammography and magnetic resonance imaging (MRI) is recommended for cancer‐susceptibility gene (BRCA) mutation carriers, there no current consensus on the optimal regimen. METHODS: The authors used a computer simulation model to compare 6 annual strategies (film [FM], digital [DM], FM [MRI] or DM MRI contemporaneously, alternating FM/MRI DM/MRI at 6‐month intervals) beginning ages 25 years, 30 35 40 2 of delayed DM/FM versus clinical...
Digital mammography (DM) and digital breast tomosynthesis (DBT) are used for routine cancer screening. There is minimal evidence on performance outcomes by age, screening round, density in community practice.To compare DM vs DBT baseline subsequent category.This comparative effectiveness study assessed 1 584 079 examinations of women aged 40 to 79 years without prior history cancer, mastectomy, or augmentation undergoing at 46 participating Breast Cancer Surveillance Consortium facilities...
The coronavirus disease 2019 (COVID-19) pandemic led to a near-total cessation of mammography services in the United States mid-March 2020. It is unclear if screening and diagnostic volumes have recovered prepandemic levels whether use has varied by women's characteristics.We collected data on 461 083 mammograms 112 207 conducted during January through July 2020 at 62 radiology facilities Breast Cancer Surveillance Consortium. We compared monthly before stratified age, race ethnicity, breast...
Screening mammography and magnetic resonance imaging (MRI) are recommended for women with ATM, CHEK2, PALB2 pathogenic variants. However, there few data to guide screening regimens these women.To estimate the benefits harms of breast cancer strategies using MRI at various start ages variants.This comparative modeling analysis used 2 established microsimulation models from Cancer Intervention Surveillance Modeling Network (CISNET) evaluate different strategies. Age-specific risks were...
Background Contrast-enhanced mammography (CEM) and abbreviated breast MRI (ABMRI) are emerging alternatives to standard for supplemental cancer screening. Purpose To compare the diagnostic performance of CEM, ABMRI, MRI. Materials Methods This single-institution, prospective, blinded reader study included female participants referred from January 2018 June 2021. CEM was performed within 14 days MRI; ABMRI produced images. Two readers independently interpreted each after a washout period....
Women with polycystic ovary syndrome (PCOS) commonly have insulin resistance. Insulin resistance is associated marked abnormalities of lipoprotein size and subclass particle concentration. The purpose this study was to examine the effects a moderate-intensity exercise program without weight loss on profiles in women PCOS.Thirty-seven sedentary PCOS were randomized either an 8- 12-wk ramp-up followed by (16-24 wk total, approximately 228 min x at 40-60% peak V O2, n = 21) or control (no...
Purpose To determine whether the rates and tumor characteristics of screening-detected interval cancers differ for two-dimensional digital mammography (DM) versus breast tomosynthesis (DBT) mammography. Materials Methods Consecutive screening mammograms from January 2009 to February 2011 (DM group, before DBT integration) 2013 2015 (DBT after complete were reviewed. Cancers considered detected if diagnosed within 365 days a positive examination negative examination. Z tests used compare on...
Abstract BACKGROUND: Current clinical guidelines recommend earlier, more intensive breast cancer screening with both magnetic resonance imaging (MRI) and mammography for women susceptibility gene ( BRCA ) mutations. Unspecified details of schedules are a challenge implementing guidelines. METHODS: A Markov Monte Carlo computer model was used to simulate in asymptomatic who were BRCA1 BRCA2 mutation carriers. Three dual‐modality strategies compared digital (DM) alone: 1) DM MRI alternating at...
Abstract Background Digital breast tomosynthesis (DBT) is increasingly being used for routine cancer screening. We projected the long-term impact and cost-effectiveness of DBT compared to conventional digital mammography (DM) screening in United States. Methods Three Cancer Intervention Surveillance Modeling Network models simulated US women ages 40 years older undergoing with either or DM starting 2011 continuing lifetime cohort. Screening performance estimates were based on observational...
Background Prior cross-sectional studies have observed that breast cancer screening with digital tomosynthesis (DBT) has a lower recall rate and higher detection compared mammography (DM). Purpose To evaluate outcomes DBT versus DM on successive rounds. Materials Methods In this retrospective cohort study, data from 58 imaging facilities in the Breast Cancer Surveillance Consortium were collected. Analysis included women aged 40-79 years undergoing or 2011 to 2020. Absolute differences by...
To determine consensus, using Delphi methodology, on the critical procedural steps for intravascular intrauterine transfusion (IUT) treatment of fetal anemia.
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Background Performance metrics with digital breast tomosynthesis (DBT) are based on early experiences. There is limited research whether the benefits of DBT sustained. Purpose To determine improved screening performance sustained over time at population level and after first round individual level. Materials Methods A retrospective review was conducted mammograms that had been obtained before implementation (March 2008 to February 2011, two-dimensional mammography [DM] group) for 5 years...
Surveillance with annual mammography and breast magnetic resonance imaging (MRI) is recommended for female survivors of childhood cancer treated chest radiation, yet benefits, harms, costs are uncertain.
Background The COVID-19 pandemic reduced mammography use, potentially delaying breast cancer diagnoses. Purpose To examine biopsy recommendations and cancers diagnosed before during the by mode of detection (screen detected vs symptomatic) women's characteristics. Materials Methods In this secondary analysis prospectively collected data, monthly after mammography, US, or both with subsequent performed were examined from 66 facilities Breast Cancer Surveillance Consortium between January 2019...
Background Since 2007, digital mammography and breast tomosynthesis (DBT) replaced screen-film mammography. Whether these technologic advances have improved diagnostic performance has, to the knowledge of authors, not yet been established. Purpose To evaluate outcomes surveillance (digital DBT) performed from 2007 2016 in women with a personal history cancer compare data 1996 screening benchmarks. Materials Methods In this observational cohort study, five Breast Cancer Surveillance...