A5022161001- HIV Research and Treatment
- Acute Ischemic Stroke Management
- HIV-related health complications and treatments
- Peripheral Neuropathies and Disorders
- HIV/AIDS Research and Interventions
- Neuroinflammation and Neurodegeneration Mechanisms
- Autism Spectrum Disorder Research
- Stroke Rehabilitation and Recovery
- Nail Diseases and Treatments
- Botulinum Toxin and Related Neurological Disorders
- Global Public Health Policies and Epidemiology
- Autoimmune Neurological Disorders and Treatments
- Health Systems, Economic Evaluations, Quality of Life
- Telemedicine and Telehealth Implementation
- Monoclonal and Polyclonal Antibodies Research
- Cerebrovascular and Carotid Artery Diseases
- Ophthalmology and Visual Health Research
- Musculoskeletal Disorders and Rehabilitation
- Systemic Lupus Erythematosus Research
- Nanocluster Synthesis and Applications
- Papaya Research and Applications
- Mosquito-borne diseases and control
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Pharmacological Effects and Toxicity Studies
- Fungal Infections and Studies
University of Nairobi
2013-2024
Groote Schuur Hospital
2022
Kenyatta National Hospital
2018-2019
Kenya Medical Research Institute
2010-2013
University of California, San Francisco
2011
<b><i>Background:</i></b> Between 0 and 48% of normal HIV-uninfected individuals score below threshold neuropsychological test scores for HIV-associated neurocognitive disorders (HAND) or are false positives. There has been little effort to understand the effect varied interpretations research criteria HAND on false-positive frequencies, prevalence analytic estimates. <b><i>Methods:</i></b> The proportion scoring Z thresholds drawn from HAND,...
<b><i>Background:</i></b> Despite the increasing global burden of stroke, there are limited data on stroke from Kenya to guide in decision-making. Stroke occurrence sub-Saharan Africa has been associated with poor health outcomes. This study sought establish incidence density and mortality Kenya’s leading public tertiary hospitals for purposes informing clinical practice policy. <b><i>Methods:</i></b> is a prospective conducted at referral...
Abstract Background Parkinson’s disease (PD) is the second most common neurodegenerative disorder and, according to Global Burden of Disease estimates in 2015, was fastest growing neurological globally with respect associated prevalence, disability, and deaths. Information regarding awareness, diagnosis, phenotypic characteristics, epidemiology, risk factors, treatment, economic impact lived experiences people PD from African perspective relatively sparse contrast developed world, much...
Neuropathy is the most common neurologic complication of HIV but widely under-diagnosed in resource-constrained settings. We aimed to identify tools that accurately distinguish individuals with moderate/severe peripheral neuropathy and can be administered by non-physician healthcare workers (HCW) settings.We enrolled a convenience sample 30 HIV-infected outpatients from Kenyan HIV-care clinic. A HCW Severity Score (NSS), Single Question Screen (Single-QNS), Subjective Peripheral...
Objective To conduct a preliminary evaluation of the utility and reliability diagnostic tool for HIV-associated dementia (HAD) use by primary health care workers (HCW) which would be feasible to implement in resource-limited settings. Background In settings, HAD is an indication anti-retroviral therapy regardless CD4 T-cell count. Anti-retroviral therapy, treatment HAD, now increasingly available Nonetheless, remains under-diagnosed likely because limited clinical expertise availability...
Cardiovascular diseases are the second leading cause of morbidity and mortality in Kenya. However, there is limited clinic-epidemiological data on stroke to inform decision making. This study sought establish distribution patterns characteristics patients seeking care at Kenyatta National Hospital (KNH) Moi Teaching Referral (MTRH), with ultimate aim establishing first national registry Kenya.This was a prospective multicentre cohort among patients. The used modified World Health...
ABSTRACT Introduction Peripheral neuropathy is the most common neurological complication of human immunodeficiency virus (HIV) infection but widely under‐diagnosed in resource‐limited settings. We investigated utility screening tools administered by nonphysician healthcare workers (HCW) and quantitative sensory testing (QST) trained individuals for identification moderate/severe neuropathy. Methods enrolled 240 HIV‐infected outpatients using 2‐stage cluster randomized sampling. HCWs several...
Very little is known about the experience of people living with Parkinson's disease (PD) in low- and middle-income countries, such as those sub-Saharan Africa. The number specialists region low awareness limited among population healthcare professionals. Drawing on ten months ethnographic fieldwork urban rural Kenya 55 PD (PwP), 23 family members 22 professionals from public private clinics, we set out to understand diagnosis PwP Kenya. diagnostic journeys our study participants were...
Abstract Background The accessibility of Parkinson's disease medicines is limited across sub‐Saharan Africa, which can have negative health, social and financial consequences for people with their families. However, there a stark gap in the literature regarding impact poor access to on individuals. Objectives study objective was understand Kenya from perspective disease, caregivers neurologists. Methods In‐depth qualitative interviews were conducted 55 23 8 neurologists experience challenges...
<b><i>Background:</i></b> There is little information on stroke morbidity in Kenya to inform health care planning. The disability-adjusted life-years (DALYs) are a time-based measure of status that incorporates both disability and mortality. <b><i>Methods:</i></b> This was multicenter prospective study Kenya’s public tertiary hospitals conducted 2015–2017. Data sex, age, global outcome were collected used calculate the sum years life lost...