A5056498180- Oral microbiology and periodontitis research
- Vibrio bacteria research studies
- Gut microbiota and health
- Child Nutrition and Water Access
- Dental Health and Care Utilization
- Streptococcal Infections and Treatments
- Urinary Tract Infections Management
- Microbial Community Ecology and Physiology
- Antibiotic Resistance in Bacteria
- Bacterial Identification and Susceptibility Testing
- HIV/AIDS oral health manifestations
- Otolaryngology and Infectious Diseases
- Clostridium difficile and Clostridium perfringens research
- Dental Research and COVID-19
- Microbial bioremediation and biosurfactants
- Pharmacological Effects of Natural Compounds
- Identification and Quantification in Food
- Genital Health and Disease
- Microbial Metabolic Engineering and Bioproduction
- Hepatitis B Virus Studies
- Infective Endocarditis Diagnosis and Management
- Molecular Biology Techniques and Applications
- Cervical Cancer and HPV Research
- Computational Drug Discovery Methods
- Essential Oils and Antimicrobial Activity
University of Lagos
2016-2025
Nigerian Institute of Medical Research
2012-2025
Lagos University Teaching Hospital
2024
Bridge University
2023
University of Calabar
2023
Abstract Background One of the main challenges wound healing is infection with multi-drug resistant (MDR) bacteria such as Staphylococcus aureus. The spectrum antibiotics used to treat them declining; thus, there a need for alternatives. Our study was designed evaluate antimicrobial properties honey, its pharmacokinetics (ADMET) and in-silico analysis bioactive compounds against dihydropteroate synthase S. aureus using trimethoprim control. Methods Standard protocols were employed in...
The expected reduction in cervical cancer incidence as a result of increased access to antiretroviral therapy is yet be seen. In this study we investigated the effect HIV infection and treatment on high-risk (hr) human papilloma virus (HPV) prevalence distribution. Cervical cells from 515 (220 positive 295 negative) women, recruited during community screening programme states Ogun Lagos at screen clinic, Nigerian Institute Medical Research were evaluated for presence 13 hr HPV genotypes by...
Staphylococcus aureus has prevailed against the majority of antibiotics currently in clinical use, making it a significant global public health problem. As safer alternative, bioactive compounds have been explored. Annona muricata shown to possess antimicrobial activity. However, there are few reports on molecular activity A. S. aureus. Thus, this study was aimed at evaluating its crude extract as well investigating potential Cap5O capsular polysaccharides (CPS) via docking.Collection plant...
Abstract Elucidating the genetic contributions to Parkinson’s disease (PD) etiology across diverse ancestries is a critical priority for development of targeted therapies in global context. We conducted largest sequencing characterization potentially disease-causing, protein-altering and splicing mutations 710 cases 11,827 controls from genetically predicted African or admixed ancestries. explored copy number variants (CNVs) runs homozygosity (ROHs) prioritized early onset familial cases....
Background : The catechol-O-methyltransferase ( COMT ) gene is involved in brain catecholamine metabolism, but its association with Parkinson′s disease (PD) risk remains unclear. Objective To investigate the relationship between genetic variants and PD across diverse ancestries. Methods We analyzed 2,251 patients 2,835 controls of European descent using whole-genome sequencing from Accelerating Medicines Partnership-Parkinson Disease (AMP-PD), along 20,427 11,837 10 ancestries genotyping...
Conjunctivitis, an inflammation of the conjunctiva, is one most common eye problems affecting all age groups in Nigeria. A better understanding its epidemiology and antibiotic susceptibility etiologic bacterial agents crucial for initiation preventive therapeutic measures. This study determined distribution patterns infections Nigerian patients with conjunctivitis. Antibiotic resistance plasmid profiles these pathogens were also investigated.A total 83 consecutive non-duplicate conjunctival...
Abstract Background Parkinson’s disease (PD) is the second most common neurodegenerative disorder and, according to Global Burden of Disease estimates in 2015, was fastest growing neurological globally with respect associated prevalence, disability, and deaths. Information regarding awareness, diagnosis, phenotypic characteristics, epidemiology, risk factors, treatment, economic impact lived experiences people PD from African perspective relatively sparse contrast developed world, much...
Aim: The study was conducted to assess the knowledge and perception of probiotics among medical science students practitioners in Lagos state. Study Design: This is a questionnaire based survey. Place Duration Study: state which located south-western part Nigeria. questionnaires were distributed from March August, 2013. Methodology: Predesigned pilot tested randomly administered 270 professionals various health institutes level scored 0-3 as poor, 4-6 fair 7-9 good analyzed using Epi info...
The aim of this study was to evaluate the occurrence yeasts, pseudomonads and enteric bacteria in oral cavity patients undergoing radiotherapy (RT) for treatment head neck cancer. Fifty receiving RT were examined before, during 30 days after RT. Saliva, mucosa, biofilm samples collected microorganisms detected by culture polymerase chain reaction (PCR). most prevalent yeasts submitted Candida albicans, C. tropicalis, krusei, glabrata parapsilosis. Citrobacter, Enterobacter, Enterococcus,...