Elisabete Weiderpass
- Cancer Risks and Factors
- Nutritional Studies and Diet
- Global Cancer Incidence and Screening
- Ovarian cancer diagnosis and treatment
- Estrogen and related hormone effects
- Cervical Cancer and HPV Research
- Colorectal Cancer Screening and Detection
- Cancer, Lipids, and Metabolism
- Endometrial and Cervical Cancer Treatments
- Obesity, Physical Activity, Diet
- Occupational and environmental lung diseases
- Liver Disease Diagnosis and Treatment
- Diet and metabolism studies
- Nutrition and Health in Aging
- Bladder and Urothelial Cancer Treatments
- Alcohol Consumption and Health Effects
- Air Quality and Health Impacts
- Nutrition, Genetics, and Disease
- Folate and B Vitamins Research
- BRCA gene mutations in cancer
- Carcinogens and Genotoxicity Assessment
- Metabolism, Diabetes, and Cancer
- Genetic Associations and Epidemiology
- Consumer Attitudes and Food Labeling
- Epigenetics and DNA Methylation
Centre International de Recherche sur le Cancer
2005-2025
UiT The Arctic University of Norway
2013-2024
John Wiley & Sons (United States)
2016-2024
Hudson Institute
2022-2024
Liechtenstein Institute
2024
Cancer Registry of Norway
2012-2023
Karolinska Institutet
2012-2023
Folkhälsans Forskningscentrum
2012-2023
Medical Research Council
2016-2023
British Heart Foundation
2016-2023
The knowledge that persistent human papillomavirus (HPV) infection is the main cause of cervical cancer has resulted in development prophylactic vaccines to prevent HPV and assays detect nucleic acids virus. WHO launched a Global Initiative scale up preventive, screening, treatment interventions eliminate as public health problem during 21st century. Therefore, our study aimed assess existing burden baseline from which effect this initiative.
A high body-mass index (BMI, the weight in kilograms divided by square of height meters) is associated with increased mortality from cardiovascular disease and certain cancers, but precise relationship between BMI all-cause remains uncertain.
<h3>Importance</h3> Liver cancer is among the leading causes of deaths globally. The most common for liver include hepatitis B virus (HBV) and C (HCV) infection alcohol use. <h3>Objective</h3> To report results Global Burden Disease (GBD) 2015 study on primary incidence, mortality, disability-adjusted life-years (DALYs) 195 countries or territories from 1990 to 2015, present global, regional, national estimates burden attributable HBV, HCV, alcohol, an "other" group that encompasses residual...
The relative importance of cardiovascular disease (CVD) and cancer as leading causes premature death are examined in this communication. CVD now the 127 countries, with 70 countries (including Brazil India) 57 China). Such observations can be seen part a late phase an epidemiologic transition, taking place second half 20th century first present one, which dominance infectious diseases is progressively superseded by noncommunicable diseases. According to ranks recent trends, may surpass cause...
Leisure-time physical activity has been associated with lower risk of heart-disease and all-cause mortality, but its association cancer is not well understood.
The 2008 Physical Activity Guidelines for Americans recommended a minimum of 75 vigorous-intensity or 150 moderate-intensity minutes per week (7.5 metabolic-equivalent hours week) aerobic activity substantial health benefit and suggested additional benefits by doing more than double this amount. However, the upper limit longevity possible harm with physical is unclear.
BackgroundLow-risk limits recommended for alcohol consumption vary substantially across different national guidelines. To define thresholds associated with lowest risk all-cause mortality and cardiovascular disease, we studied individual-participant data from 599 912 current drinkers without previous disease.MethodsWe did a combined analysis of three large-scale sources in 19 high-income countries (the Emerging Risk Factors Collaboration, EPIC-CVD, the UK Biobank). We characterised...
We present up to 45 years of cancer incidence data by occupational category for the Nordic populations. The study covers 15 million people aged 30–64 in 1960, 1970, 1980/1981 and/or 1990 censuses Denmark, Finland, Iceland, Norway and Sweden, 2.8 incident cases diagnosed these a follow-up until about 2005. was undertaken as cohort with linkage individual records based on personal identity codes used all countries.In censuses, information occupation each person provided through free text...
Analyzing data from over 650,000 individuals, Dr. Steven Moore and colleagues report that greater amounts of leisure-time physical activity were associated with higher life expectancy across a wide range levels body mass index groups.
Although cancer has been clearly associated with venous thromboembolism (VTE), many aspects of this relation are poorly understood, including the sites most affected and risk during long-term follow-up. To clarify these relations, we carried out a large, population-based analysis VTE risk.Using Swedish Inpatient Register linkage to nationwide Cancer Registry, assessed incidence 1989 among 61,998 patients without previous diagnosis admitted hospital between 1965 1983 for VTE. measure possible...
Multiple myeloma (MM) is a plasma cell neoplasm with substantial morbidity and mortality. A comprehensive description of the global burden MM needed to help direct health policy, resource allocation, research, patient care.To describe availability effective therapies for 21 world regions 195 countries territories from 1990 2016.We report incidence, mortality, disability-adjusted life-year (DALY) estimates Global Burden Disease 2016 study. Data sources include vital registration system,...
Brain and CNS cancers (collectively referred to as cancers) are a source of mortality morbidity for which diagnosis treatment require extensive resource allocation sophisticated diagnostic therapeutic technology. Previous epidemiological studies limited specific geographical regions or time periods, making them difficult compare on global scale. In this analysis, we aimed provide comparable comprehensive estimation the burden brain cancer between 1990 2016.We report means 95% uncertainty...
BACKGROUND: Unopposed estrogen replacement therapy (i.e., without progestins) increases the risk of endometrial cancer. In this study, we examined cancer associated with combined estrogen-progestin regimens currently in use, since safety profiles these have not been clearly defined. METHODS: We conducted a nationwide population-based, case-control study Sweden postmenopausal women aged 50-74 years. collected information on use hormone from 709 case patients incident and 3368 control...
An understanding of the etiologic heterogeneity ovarian cancer is important for improving prevention, early detection, and therapeutic approaches. We evaluated 14 hormonal, reproductive, lifestyle factors by histologic subtype in Ovarian Cancer Cohort Consortium (OC3).
In a pooled analysis of 20 prospective studies, Cari Kitahara and colleagues find that class III obesity (BMI 40–59) is associated with excess rates total mortality, particularly due to heart disease, cancer, diabetes. Please see later in the article for Editors' Summary
Abstract Rapid increases in cervical adenocarcinoma incidence have been observed Western countries recent decades. Postulated explanations include an increasing specificity of subtype—the capability to diagnose the disease, inability cytologic screening reduce adenocarcinoma, and heterogeneity cofactors related persistent human papillomavirus infection. This study examines possible contribution these factors relation with trends Europe. Age-period-cohort models were fitted women ages...
BackgroundEarly menopause is linked to an increased risk of cardiovascular disease mortality; however, the association between early and incidence timing unclear. We aimed assess associations age at natural disease.MethodsWe harmonised pooled individual-level data from 15 observational studies done across five countries regions (Australia, Scandinavia, USA, Japan, UK) 1946 2013. Women who had reported their status, (if postmenopausal), status (including coronary heart stroke) were included....
Abstract Despite there being sufficient evidence for the effectiveness of screening by cytology in preventing cancer cervix uteri, policies vary widely among European countries, and incidence is increasing younger women. This study analyzes trends squamous cell carcinoma (SCC) uteri 13 countries to evaluate against a background changing risk. Age-period-cohort models were fitted period cohort effects estimated; these considered as primarily indicative interventions etiology, respectively. A...
<h3>Objective</h3> About 20 years ago, the scientific community was first alerted to an enigmatic increase of oesophageal adenocarcinomas in UK and USA. Subsequently, a virtual epidemic—still unexplained—was confirmed several western countries. Detailed descriptive data might provide clues its causes. <h3>Design</h3> We collected on incident cases adenocarcinoma from population-based cancer registries Australia, Europe, North America Asia. calculated age-standardised incidence rates fitted...
Background: The higher risk of death resulting from excess adiposity may be attenuated by physical activity (PA). However, the theoretical number deaths reduced eliminating inactivity compared with overall and abdominal obesity remains unclear. Objective: We examined whether modified association between PA all-cause mortality estimated population attributable fraction (PAF) years life gained for these exposures. Design: This was a cohort study in 334,161 European men women. mean follow-up...