Laufey Tryggvadóttír

ORCID: 0000-0001-8067-9030
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About
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Research Areas
  • Cancer Risks and Factors
  • Global Cancer Incidence and Screening
  • BRCA gene mutations in cancer
  • Childhood Cancer Survivors' Quality of Life
  • Occupational and environmental lung diseases
  • Acute Lymphoblastic Leukemia research
  • Colorectal Cancer Screening and Detection
  • Nutritional Studies and Diet
  • Genetic factors in colorectal cancer
  • Air Quality and Health Impacts
  • Carcinogens and Genotoxicity Assessment
  • Cervical Cancer and HPV Research
  • Cancer Genomics and Diagnostics
  • Cutaneous Melanoma Detection and Management
  • Esophageal Cancer Research and Treatment
  • Nutrition, Genetics, and Disease
  • Ovarian cancer diagnosis and treatment
  • Epigenetics and DNA Methylation
  • Genetic Associations and Epidemiology
  • Multiple and Secondary Primary Cancers
  • DNA Repair Mechanisms
  • Nonmelanoma Skin Cancer Studies
  • Gastroesophageal reflux and treatments
  • Cancer-related Molecular Pathways
  • Endometrial and Cervical Cancer Treatments

Icelandic Cancer Society
2015-2024

University of Iceland
2015-2024

London School of Hygiene & Tropical Medicine
2016-2022

London Cancer
2021-2022

Norwegian University of Science and Technology
2020

Karolinska University Hospital
2020

Karolinska Institutet
2012-2020

Aarhus University Hospital
2019

Cancer Registry of Norway
2002-2018

Finnish Cancer Registry
2011-2018

We present up to 45 years of cancer incidence data by occupational category for the Nordic populations. The study covers 15 million people aged 30–64 in 1960, 1970, 1980/1981 and/or 1990 censuses Denmark, Finland, Iceland, Norway and Sweden, 2.8 incident cases diagnosed these a follow-up until about 2005. was undertaken as cohort with linkage individual records based on personal identity codes used all countries.In censuses, information occupation each person provided through free text...

10.1080/02841860902913546 article EN Acta Oncologica 2009-01-01

Multiple genetic loci confer susceptibility to breast and ovarian cancers. We have previously developed a model (BOADICEA) under which cancer is explained by mutations in BRCA1 BRCA2, as well the joint multiplicative effects of many genes (polygenic component). now updated BOADICEA using additional family data from two UK population-based studies BRCA2 carriers identified 22 or cancer. The combined set includes 2785 families (301 positive 236 positive). Incidences were smoothed locally...

10.1038/sj.bjc.6604305 article EN cc-by-nc-sa British Journal of Cancer 2008-03-18
Gemma Gatta Laura Botta María‐José Sánchez Lesley Anderson Daniela Pierannunzio and 95 more Lisa Licitra Monika Hackl N. Zielonke Willi Oberaigner E. Van Eycken K. Henau Z. Valerianova Nadya Dimitrova Mario Šekerija Miroslav Zvolský Ladislav Dušek Hans H. Storm Gerda Engholm Margit Mägi Tiiu Aareleid Nea Malila Karri Seppä Michel Velten X. Troussard Véronique Bouvier Guy Launoy A.V. Guizard Jean Faivre Anne‐Marie Bouvier P. Arveux Marc Maynadié Anne‐Sophie Woronoff Michel Robaszkiewicz Isabelle Baldi Alain Monnereau Brigitte Trétarre Nadine Bossard Aurélien Belot Marc Colonna F. Molinié S. Bara C. Schvartz B. Lapôtre‐Ledoux Pascale Grosclaude M. Meyer Roland Stabenow Sabine Luttmann Andrea Eberle Hermann Brenner Alice Nennecke Jutta Engel G. Schubert-Fritschle Joachim Kieschke Jan Heidrich Bernd Holleczek Alexander Katalinic Jón G. Jónasson Laufey Tryggvadóttír Harry Comber Guido Mazzoleni A. Bulatko Carlotta Buzzoni Adriano Giacomin A. Mazzei A. Sutera Sardo Stefano Ferretti Emanuele Crocetti Gianfranco Manneschi Gemma Gatta Milena Sant H. Amash C. Amati Paolo Baili Franco Berrino S. Bonfarnuzzo Laura Botta F. Di Salvo Roberto Foschi C. Margutti E. Meneghini Pamela Minicozzi Annalisa Trama Diego Serraino Antonella Zucchetto Roberta De Angelis M. Caldora Riccardo Capocaccia E. Carrani Silvia Francisci Sandra Mallone Daniela Pierannunzio P. Roazzi Silvia Rossi Mariano Santaquilani Andrea Tavilla Fabio Pannozzo M. Natali L Bonelli Marina Vercelli Valerio Gennaro Paolo Ricci

10.1016/j.ejca.2015.07.043 article EN European Journal of Cancer 2015-09-25
Simon Stacey Patrick Sulem Áslaug Jónasdóttir Gísli Másson Jūlı́us Guðmundsson and 95 more Daníel F. Guðbjartsson Ólafur Þ. Magnússon Sigurjón A. Guðjónsson Bárður Sigurgeirsson Kristin Thorisdottir Rafn Ragnarsson Kristrún R. Benediktsdóttir Bjørn A. Nexø Anne Tjønneland Kim Overvad Péter Rudnai Eugen Gurzău Kvetoslava Koppová Kari Hemminki Cristina Corredera Victoria Fuentelsaz Pilar Grasa Sebastián Navarrete Fernando Fuertes María Dolores García-Prats Enrique Sanambrosio Angeles Panadero Ana De Juan Almudena García Fernando Rivera Dolores Planelles Vincent Soriano Celia Requena Katja K.H. Aben Michelle M. van Rossum R.G.H.M. Cremers Inge M. van Oort Dick-Johan van Spronsen Jack A. Schalken Wilbert H.M. Peters Brian T. Helfand Jenny Donovan Freddie C. Hamdy D. Badescu O. Codreanu Mariana Jinga Irma Eva Csiki Vali Constantinescu P Badea Ioan Nicolae Mateș Daniela Dinu Adrian Constantin Dana Mateș Sjöfn Kristjánsdóttir Bjarni A. Agnarsson Eiríkur Jónsson Rósa B. Barkardóttir Guðmundur Einarsson Fridbjörn Sigurdsson Páll Helgi Möller Tryggvi Stefánsson Trausti Valdimarsson Oskar T. Johannsson Helgi Sigurðsson Þorvaldur Jónsson Jón G. Jónasson Laufey Tryggvadóttír Terri Rice Helen M. Hansen Yuanyuan Xiao Daniel H. Lachance Brian Patrick O’Neill Matthew Kosel Paul A. Decker Guðmar Þorleifsson Hrefna Johannsdottir Hafdís T. Helgadóttir Ásgeir Sigurðsson Valgerður Steinthórsdóttir Annika Lindblom Robert S. Sandler Temitope O. Keku Karina Banasik Torben Jørgensen Daniel R. Witte Torben Hansen Oluf Pedersen Viorel Jinga David E. Neal William J. Catàlona Margaret Wrensch John K. Wiencke Robert B. Jenkins Eduardo Nagore Ulla Vogel Lambertus A. Kiemeney Rajiv Kumar José Mayordomo Jón Ólafsson Augustine Kong

10.1038/ng.926 article EN Nature Genetics 2011-09-25

Background: The Nordic Cancer Registries are among the oldest population-based registries in world, with more than 60 years of complete coverage what is now a combined population 26 million. However, despite being source substantial number studies, there no published paper comparing different registries. Therefore, we did systematic review to identify similarities and dissimilarities Registries, which could possibly explain some differences cancer incidence rates across these...

10.1080/0284186x.2017.1407039 article EN Acta Oncologica 2017-12-11
Milena Sant María Dolores Chirlaque López Roberto Agresti María‐José Sánchez Bernd Holleczek and 95 more Magdalena Bielska‐Lasota Nadya Dimitrova Kaire Innos Alexander Katalinic Hilde Langseth Nerea Larrañaga Silvia Rossi Sabine Siesling Pamela Minicozzi Monika Hackl N. Zielonke Willi Oberaigner E. Van Eycken K. Henau Z. Valerianova Nadya Dimitrova Mario Šekerija Miroslav Zvolský Ladislav Dušek Hans H. Storm Gerda Engholm Margit Mägi Tiiu Aareleid Nea Malila Karri Seppä Michel Velten X. Troussard Véronique Bouvier Guy Launoy A.V. Guizard Jean Faivre Anne‐Marie Bouvier P. Arveux Marc Maynadié Anne‐Sophie Woronoff Michel Robaszkiewicz Isabelle Baldi Alain Monnereau Brigitte Trétarre Nadine Bossard Aurélien Belot Marc Colonna F. Molinié S. Bara C. Schvartz B. Lapôtre‐Ledoux Pascale Grosclaude M. Meyer Roland Stabenow Sabine Luttmann Andrea Eberle Hermann Brenner Alice Nennecke Jutta Engel G. Schubert-Fritschle Joachim Kieschke Jan Heidrich Bernd Holleczek Alexander Katalinic Jón G. Jónasson Laufey Tryggvadóttír Harry Comber Guido Mazzoleni A. Bulatko Carlotta Buzzoni Adriano Giacomin A. Sutera Sardo Pamela Mancuso Stefano Ferretti Emanuele Crocetti Adele Caldarella Gemma Gatta Milena Sant H. Amash C. Amati Paolo Baili Franco Berrino S. Bonfarnuzzo Laura Botta F. Di Salvo Roberto Foschi C. Margutti E. Meneghini Pamela Minicozzi Annalisa Trama Diego Serraino Luigino Dal Maso Roberta De Angelis M. Caldora Riccardo Capocaccia E. Carrani Silvia Francisci Sandra Mallone Daniela Pierannunzio P. Roazzi

10.1016/j.ejca.2015.07.022 article EN European Journal of Cancer 2015-09-25

Melanoma is a significant health problem in Caucasian populations. The most recently available data from cancer registries often have delay of several months up to few years and they are generally not easily accessible.To assess recent age- sex-specific trends melanoma incidence make predictions for 2010 2015.A retrospective registry-based analysis was performed with 29 European registries. Most them had 1990 2006/7. World-standardized rates (WSR) the estimated annual percentage change...

10.1111/jdv.12236 article EN Journal of the European Academy of Dermatology and Venereology 2013-08-21

The quadrivalent human papillomavirus (qHPV) vaccine prevented HPV type-related infection and disease in young women the 4-year FUTURE II efficacy study (NCT00092534). We report long-term effectiveness immunogenicity at end of 14 years follow-up after enrollment II.Young (16-23 age) from Denmark, Iceland, Norway, Sweden who received three qHPV doses during randomized, double-blind, placebo-controlled base were followed for an additional ≥10 through national registries. Tissue samples...

10.1016/j.eclinm.2020.100401 article EN cc-by-nc-nd EClinicalMedicine 2020-06-01

Methods. We conducted a population-based cross-sectional study in 69,147 women (18–45 years of age) randomly chosen from the general population Denmark, Iceland, Norway, and Sweden. Information on clinically diagnosed genital warts lifestyle habits was collected using questionnaire.

10.1086/522863 article EN The Journal of Infectious Diseases 2007-11-15

Mutations in the BRCA2 gene are associated with an increased risk of prostate cancer, but it is not known whether they progression disease. We compared cancer-specific survival, disease stage, and tumor grade between cancer patients carrying Icelandic 999del5 founder mutation noncarriers.Using population-based registries, we identified all 596 who were diagnosed Iceland during 1955 through 2004 among 29603 male relatives unselected breast probands. status could be determined for 527 (88.4%)....

10.1093/jnci/djm005 article EN cc-by-nc JNCI Journal of the National Cancer Institute 2007-06-12

Trends in incidence and mortality rates of prostate cancer were analyzed using data from the national registries Denmark, Finland, Iceland, Norway, Sweden. Joinpoint regression models used to quantify temporal trends for period 1980 2004. Incidence increasing similar Nordic countries during 1980s. Around 1990, a more rapid increase began all except where an was seen 5 years later. In 2001, Denmark half those other countries, but varied only marginally among countries. Mean annual declines...

10.1093/jnci/djm249 article EN JNCI Journal of the National Cancer Institute 2007-12-11
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