A5085288243- Cancer Risks and Factors
- Global Cancer Incidence and Screening
- Colorectal Cancer Screening and Detection
- Testicular diseases and treatments
- Cancer, Lipids, and Metabolism
- Birth, Development, and Health
- Metabolism, Diabetes, and Cancer
- Genetic factors in colorectal cancer
- Ovarian cancer diagnosis and treatment
- Childhood Cancer Survivors' Quality of Life
- Nutritional Studies and Diet
- BRCA gene mutations in cancer
- Multiple and Secondary Primary Cancers
- Endometrial and Cervical Cancer Treatments
- Breast Cancer Treatment Studies
- Vitamin D Research Studies
- Pregnancy and preeclampsia studies
- Sperm and Testicular Function
- Liver Disease Diagnosis and Treatment
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Blood Pressure and Hypertension Studies
- Health, Environment, Cognitive Aging
- Sexual Differentiation and Disorders
- Viral-associated cancers and disorders
- Acute Lymphoblastic Leukemia research
Cancer Registry of Norway
2013-2023
Helsinki University Hospital
2018
Norwegian University of Science and Technology
2006-2017
Duke University Hospital
2013
Duke Medical Center
2013
Umeå University
2010-2012
King's College London
2012
Copenhagen University Hospital
2012
University of Oslo
1986-2011
Oslo University Hospital
1991-2011
Background:For unknown reasons, the age-standardized incidence of testicular cancer has shown a rapid increase in virtually all countries (mostly Western) studied. For populations with sufficiently long period registration, this development can be traced back to first half century.
This study was designed to examine the outcome of cancer lower rectum, particularly rates local recurrence and survival for tumors located in this area that have been treated by anterior or abdominoperineal resections.A prospective, observational, national, cohort which is part Norwegian Rectal Cancer Project. The present includes all patients undergoing total mesorectal excision 47 hospitals during period November 1993 December 1999. A 2,136 with rectal within 12 cm anal verge were...
Observational studies have shown inconsistent results for the association between blood pressure and cancer risk. We investigated in 7 cohorts from Norway, Austria, Sweden. In total, 577799 adults with a mean age of 44 years were followed for, on average, 12 years. Incident cancers 22184 men 14744 women, deaths 8724 4525, respectively. Cox regression was used to calculate hazard ratios per 10-mmHg increments midblood pressure, which corresponded 0.7 SDs and, example, an increment...
Experimental and epidemiological studies suggest a protective role for vitamin D in colorectal carcinogenesis, but evidence is inconclusive. Circulating 25-hydroxyvitamin (25(OH)D) concentrations that minimize risk are unknown. Current Institute of Medicine (IOM) guidance based solely on bone health.
The height and weight of 570,000 Norwegian women, aged 30-69 years, were measured the subjects then followed up for 6-18 years with regard to breast cancer morbidity mortality. They arranged in 5-year age-groups. In all age-groups tallest women found have highest risk both Overweight was a factor mortality age-groups, but it only post-menopausal case morbidity. It appeared protect against pre-menopausal age-group. Stages I II-IV follow-up endpoints show negative positive associations,...
Abstract Objective: Striking geographic variation and marked increasing secular trends characterize the incidence of testicular cancer. However, it is not known whether these patterns have attenuated in recent years they are similar for seminomas nonseminomas, two main histologic groups Method: Cancer registry data, including 27,030 cancer cases, were obtained from Denmark, Estonia, Finland, Latvia, Lithuania, Norway, Poland, Sweden. Between 57 (Denmark) 9 (Poland) registration covered....
Background: Epidemiologic studies of the families patients with ataxia-telangiectasia (A-T), a recessive genetic neurologic disorder caused by mutation ATM gene, suggest that heterozygous carriers an are at increased risk cancer. A population-based study cancer incidence in A-T unbiased selection and tracing relatives would confirm this hypothesis. Methods: We conducted Nordic countries 1218 blood 56 from 50 families. The were identified population registries, occurrence was determined...
Background Prospective studies have indicated that elevated blood glucose levels may be linked with increased cancer risk, but the strength of association is unclear. We examined between and risk in a prospective study six European cohorts. Methods Findings The Metabolic syndrome Cancer project (Me-Can) includes cohorts from Norway, Austria, Sweden; current included 274,126 men 275,818 women. Mean age at baseline was 44.8 years mean follow-up time 10.4 years. Excluding first year follow-up,...
The present study explored body mass index (BMI), height, and risk of prostate cancer in a large Norwegian cohort 950000 men aged 20-74 years, whose height weight were measured standardised way the period 1963-1999. These followed for an average 21 years. Cox proportional hazard models used analyses. During follow-up, 33 300 histologically verified cases registered. increased by both BMI height. magnitude increase was modest, relative (RR) obese (BMI>or=30) compared with normal weighted 1.09...
Trends in incidence and mortality rates of prostate cancer were analyzed using data from the national registries Denmark, Finland, Iceland, Norway, Sweden. Joinpoint regression models used to quantify temporal trends for period 1980 2004. Incidence increasing similar Nordic countries during 1980s. Around 1990, a more rapid increase began all except where an was seen 5 years later. In 2001, Denmark half those other countries, but varied only marginally among countries. Mean annual declines...
Ecological and case-control studies have demonstrated a positive correlation between consumption of fat the risk prostate cancer. Two recent human focused on α-linolenic acid as factor for Animal experiments shown that dietary ω-6 polyunsaturated fatty acids generally stimulated tumour development, whereas ω-3 diminished it. The aim our study was to investigate association these subsequent Blood donors Janus serum data bank in Norway, who later developed cancer, were matched blood without...
Knowledge of tumor growth is important in the planning and evaluation screening programs, clinical trials, epidemiological studies. Studies rates humans are usually based on small selected samples. In present study Norwegian Breast Cancer Screening Program, was estimated from a large population using new estimating procedure/model.A likelihood-based procedure used, where both screen test sensitivity were modeled as continuously increasing functions size. The method applied to cancer...
Few studies have assessed the metabolic syndrome (MetS) as an entity in relation to breast cancer risk, and results been inconsistent. We aimed examine association between MetS factors (individually combined) risk of incidence mortality.Two hundred ninety thousand women from Austria, Norway, Sweden were enrolled during 1974-2005, with measurements height, weight, blood pressure, levels glucose, cholesterol, triglycerides. Relative risks (RR) estimated using Cox proportional hazards...
Initial studies have indicated diabetes and obesity to be risk factors for hepatocellular carcinoma; but the association between other metabolic primary liver cancer (PLC) has not been investigated. The syndrome project (Me-Can) includes cohorts from Norway, Austria Sweden with data on 578,700 subjects. We used Cox proportional hazard models calculate relative risks (RRs) of PLC by body mass index (BMI), blood pressure plasma levels glucose, cholesterol triglycerides as continuous...
We investigated the association between serum levels of 25-hydroxyvitamin D (25-OHD) and risk death in Norwegian cancer patients. The study population was 658 patients with cancers breast (n = 251), colon 52), lung 210), lymphoma 145), obtained from JANUS, a population-based bank Norway. Serum samples were collected within 90 days diagnosis analyzed for 25-OHD. Patients diagnosed during 1984–2004 followed throughout 2008. used Cox regression models to assess relationship 25-OHD death. Three...
Increased attention is being paid to the long-term health and well-being of people living with a history cancer. Of particular concern cancer's effect on productivity work ability, which in turn important for persons' financial situation, life satisfaction, social relationships. We explored extent Norwegian cancer survivors stay affiliated working compared cancer-free population, quantified cancer-associated earning declines.Logistic regression models were estimated explore impact employment...
Based on observations that for certain cancers, mortality varies according to sun exposure, vitamin D has been proposed influence disease progression. This study aims investigate whether serum levels of 25(OH)D are associated with prognosis in patients prostate cancer. In total, 160 a sample the JANUS bank were included. For 123 pre-treatment was taken, whereas 37 had received hormone therapy prior blood collection. The level classified as low (< 50 nmol l−1), medium (50–80 l−1) or high (>80...
In a cardiovascular disease study in Finnmark county, Norway, which was repeated after three years (1977), 12 694 men and women twice answered questionnaire on myocardial infarction, angina pectoris, other heart diseases, atherosclerosis obliterans, stroke, diabetes. The reliability of these data is studied by using different indicators. These indicators suggest that information infarction reliable more than such stroke or For the showed an underreporting. from question diseases obliterans...
Background: There are few data on the joint influence of metabolic factors risk separate cancers. Methods: We analysed body mass index, blood pressure and plasma levels glucose, total cholesterol triglycerides from seven European cohorts comprising 564 596 men women with a mean age 44 years. weighted those equally into standardized score [MRS, = 0, standard deviation (SD) 1], an individual's level indicated as SDs sex- cohort-specific means. Cancer hazard ratios were calculated by Cox...
Objective To investigate the association between total serum cholesterol (TSC) and cancer incidence in Metabolic syndrome Cancer project (Me-Can). Methods Me-Can consists of seven cohorts from Norway, Austria, Sweden including 289,273 male 288,057 female participants prospectively followed up for (n = 38,978) with a mean follow-up 11.7 years. Cox regression models age as underlying time metric were used to estimate hazard ratios (HR) their 95% confidence intervals (CI) quintiles levels per 1...
BACKGROUND The Norwegian Breast Cancer Screening Program started in 1996. To the authors' knowledge, this is first report using individual‐based data on invitation and participation to analyze breast cancer mortality among screened nonscreened women program. METHODS Information dates of invitation, attendance, diagnosis, emigration, death, cause death was linked by unique 11‐digit personal identification numbers assigned all inhabitants Norway at birth or immigration. In total, 699,628 ages...
Epidemiological studies show an increasing trend in the incidence of neuroendocrine neoplasms (NENs). A significant number NENs occur less common primary sites, but they are often excluded from population-based studies. We studied trends all Norway according to different sites.Our analyses were based on cancer cases diagnosed between 1993 and 2010 reported national Cancer Registry Norway. total 65 morphological codes identified as stratified into 3 groups aggressiveness: low, intermediate...