- Hip and Femur Fractures
- Balance, Gait, and Falls Prevention
- Chronic Disease Management Strategies
- Bone health and osteoporosis research
- Frailty in Older Adults
- Nutrition and Health in Aging
- Cerebral Palsy and Movement Disorders
- Health Systems, Economic Evaluations, Quality of Life
- Health and Medical Studies
- Physical Activity and Health
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Liver Disease Diagnosis and Treatment
- Climate Change and Health Impacts
- Pelvic and Acetabular Injuries
- Cancer Risks and Factors
- Cancer, Lipids, and Metabolism
- Obesity, Physical Activity, Diet
- Geriatric Care and Nursing Homes
- Thermoregulation and physiological responses
- Medical Practices and Rehabilitation
- Health disparities and outcomes
- Musculoskeletal pain and rehabilitation
- Cardiac, Anesthesia and Surgical Outcomes
- Emergency and Acute Care Studies
- Health, psychology, and well-being
Robert Bosch Hospital
2016-2025
Robert Bosch Stiftung
2024
Universität Ulm
2009-2020
Zimmer Biomet (Germany)
2011-2020
Helmholtz-Institute Ulm
2005-2019
Robert Bosch (Germany)
2011-2019
University of Lübeck
2018
University Hospital Schleswig-Holstein
2018
Protestant University of Applied Sciences Freiburg
2011
The University of Sydney
2011
Background— There is evidence from recent studies that γ-glutamyltransferase (GGT) likely to be associated with cardiovascular disease (CVD). However, few date sufficient sample size and follow-up investigated the association of GGT CVD mortality. Methods Results— The relation risk death was examined in a cohort 163 944 Austrian adults monitored for up 17 years. To evaluate as an independent predictor, Cox proportional hazards models were calculated, which adjusted established factors. In...
We investigated the relation of overweight and obesity with cancer in a population-based cohort more than 145 000 Austrian adults over an average 9.9 years. Incident cancers (n=6241) were identified through state registry. Using Cox proportional-hazards models adjusted for smoking occupation, increases relative body weight men associated colon (hazard rate (HR) ratio 2.48; 95% confidence interval (CI): 1.15, 5.39 mass index (BMI) ⩾35 kg m−2) pancreatic (HR 2.34, CI: 1.17, 4.66 BMI>30...
Background Prospective studies have indicated that elevated blood glucose levels may be linked with increased cancer risk, but the strength of association is unclear. We examined between and risk in a prospective study six European cohorts. Methods Findings The Metabolic syndrome Cancer project (Me-Can) includes cohorts from Norway, Austria, Sweden; current included 274,126 men 275,818 women. Mean age at baseline was 44.8 years mean follow-up time 10.4 years. Excluding first year follow-up,...
Blood lipid levels as part of the metabolic syndrome are thought to be linked cancer risk. Few epidemiological studies have addressed association between serum triglyceride (STG) concentrations and risk.Serum were collected in a health investigation (1988-2003). The analyses included 156 153 subjects (71 693 men 84 460 women), with 5079 incident cancers 4738 women, an average 10.6 years follow-up. All malignancies ascertained from population registry. Multivariate Cox proportional hazard...
There is growing evidence for an association between obesity and asthma, but little known about the underlying mechanisms. We hypothesized that high plasma leptin low adiponectin concentrations might be related to asthma allergies in children. Plasma were measured a cross-sectional study involving 462 children aged 10 years. Information on disease symptoms diagnosis was collected by parental questioning. Multivariate linear logistic regression models used assess biomarkers disease. High...
It is assumed that nursing homes are the setting with highest incidence of hip fractures. This observation is, however, based on very little data. The aim this study was to analyze fracture rates and associated excess mortality in a large home population. A cohort >69,000 women men newly admitted German were used calculate sex- age-specific To mortality, retrospective conducted. each patient (n = 4342), four residents without 17,368) matched by sex, age, level care (measure for need care)....
To meet the special needs of older patients with fragility fractures, models for collaborative orthogeriatric care have been developed. The objective our study was to analyze association co-management mortality following hip fracture in Germany.This observational based on health insurance claims data from 58 001 (79.4% women) aged ≥80 years admitted hospital between January 2014 and March 2016. They were treated 828 German hospitals or without co-management. outcome measure cumulative...
Abstract Although several epidemiologic studies have shown that γ-glutamyltransferase (GGT) is independently associated with cardiovascular disease and all-cause mortality, its relationship cancer incidence remains widely unexplored. In experimental models, the ability of cellular GGT to modulate crucial redox-sensitive functions has been established, it thus may play a role in tumor progression, as repeatedly suggested. We prospectively investigated association between risk overall...
<b>PURPOSE</b> Within the time constraints of a typical physician-patient encounter, full patient agenda will rarely be voiced. Unexpectedly revealed issues that were neither on patient's list items for discussion nor anticipated by physician constitute an emerging agenda. We aimed to quantify occurrence rate agendas in primary care practices and explain variation between patients practices. <b>METHODS</b> This observational cross-sectional study involved 182 9 European cultural regions....
The purpose of this study was to investigate the association longitudinal change in serum gamma-glutamyltransferase (GGT) with mortality from cardiovascular disease (CVD).A population-based cohort 76,113 Austrian men and women 455,331 serial GGT measurements prospectively followed-up for a median 10.2 years after assessment during an average period 6.9 years. Cox proportional hazards regression time-varying covariates used evaluate as independent predictor CVD death. Independently baseline...
Background: in population-based studies, age and morbidity were associated with heat-related mortality. The nursing home population reveals both factors may represent a highly vulnerable subgroup. Therefore, temperature–mortality relationship was examined residents of homes.
Previous studies have shown that obesity and hypertension are associated with increased risk of renal cell carcinoma (RCC), but less is known about the association to other metabolic factors. In Metabolic Syndrome Cancer project (Me-Can) data on body mass index (BMI, kg/m2), blood pressure, circulating levels glucose, cholesterol, triglycerides were collected from 560,388 men women in cohorts Norway, Austria, Sweden. By use Cox proportional hazard models, ratios (HR) calculated for separate...
Fall incidence differs considerably between studies and countries. Reasons may be differences study samples or different assessment methods. The aim was to derive estimates of fall from two population-based among older community-living people in Germany compare retrospective prospective falls data collection Data were derived the 2008–11 wave German health interview examination survey for adults (DEGS1), Activity Function Elderly Ulm (ActiFE-Ulm). took place community facilities (DEGS1)...
To investigate the relationship between physical activity and two measures of fall incidence in an elderly population using person-years as well hours walked denominators to compare these approaches.Prospective cohort study with one-year follow-up falls calendars. Physical was defined walking duration recorded at baseline over one week a thigh-worn uni-axial accelerometer (activPAL; PAL Technologies, Glasgow, Scotland). Average daily extracted from data categorized low (0-59 min), medium...