A5066489446- Chronic Disease Management Strategies
- Diabetes Management and Education
- Diabetes Management and Research
- Health and Medical Studies
- Health Systems, Economic Evaluations, Quality of Life
- Diabetes and associated disorders
- Diabetes Treatment and Management
- Health Promotion and Cardiovascular Prevention
- Clinical practice guidelines implementation
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Diabetic Foot Ulcer Assessment and Management
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Obesity and Health Practices
- Diet and metabolism studies
- Mental Health Treatment and Access
- Hip and Femur Fractures
- Childhood Cancer Survivors' Quality of Life
- Health Literacy and Information Accessibility
- Family Support in Illness
- Chronic Kidney Disease and Diabetes
- Acute Myocardial Infarction Research
- Gestational Diabetes Research and Management
- Cardiovascular Function and Risk Factors
- Health, psychology, and well-being
- Cardiac Health and Mental Health
Heinrich Heine University Düsseldorf
2016-2025
Düsseldorf University Hospital
2008-2025
Deutsches Diabetes-Zentrum e.V.
2016-2025
German Center for Diabetes Research
2016-2025
German Institute of Human Nutrition
2019-2023
University Hospital Cologne
2023
University of Cologne
2023
Philipps University of Marburg
2023
Gesundheitsdienst
2021
Charité - Universitätsmedizin Berlin
2019
There is a dearth of long-term data regarding patient and limb survival in patients with diabetic foot ulcers (DFUs). The purpose our study was therefore to prospectively investigate the person DFU during follow-up period more than 10 years.Two hundred forty-seven DFUs without previous major amputation consecutively presenting single diabetes center between June 1998 December 1999 were included this followed up until May 2011. Mean age 68.8 ± 10.9 years, 58.7% male, 55.5% had peripheral...
It is assumed that nursing homes are the setting with highest incidence of hip fractures. This observation is, however, based on very little data. The aim this study was to analyze fracture rates and associated excess mortality in a large home population. A cohort >69,000 women men newly admitted German were used calculate sex- age-specific To mortality, retrospective conducted. each patient (n = 4342), four residents without 17,368) matched by sex, age, level care (measure for need care)....
Epidemiological data about pelvic fractures are limited. Until today, most studies only analyzed inpatient data. The purpose of this study was to estimate incidence rates in the German population aged 60 years or older, based on outpatient and We conducted a retrospective population-based observational routine from large health insurance company Germany. Age sex-specific first between 2008 2011 were calculated. also standardized with respect age sex population. Multiple Poisson regression...
The German Diabetes Study (GDS) is a prospective longitudinal cohort study describing the impact of subphenotypes on course disease. GDS aims at identifying prognostic factors and mechanisms underlying development related comorbidities.The comprises intensive phenotyping within 12 months after clinical diagnosis, 5-year intervals for 20 years annual telephone interviews in between. Dynamic tests, including glucagon, mixed meal, intravenous glucose tolerance hyperinsulinemic clamp serve to...
Diabet. Med. 29, e88–e95 (2012) Abstract Aim In Germany, regional data on the prevalence of Type 2 diabetes mellitus are lacking for health‐care planning and detection risk factors associated with this disease. We analysed variations in treatment antidiabetic agents. Methods Data subjects aged 45–74 years from five population‐based studies one nationwide study conducted between 1997 2006 were analysed. Information self‐reported diabetes, treatment, diagnosis compared. estimates (95%...
To compare clinical characteristics and outcome of type 1 diabetes mellitus (T1DM) between patients with without a clinically recognized eating disorder (ED).A total 52,215 T1DM aged 8 to <30 years from the prospective data acquisition system DPV were analyzed. A 467 had an additional diagnosis ED according DSM-IV criteria (anorexia nervosa [AN], n = 141 [female: 94.3%]; bulimia [BN], 62 [90.3%]; EDs not otherwise specified, including binge-eating [EDNOS], 264 [74.2%]). Groups compared using...
To describe for the first time direct costs of Type 2 diabetes treatment by analysing nationwide routine data from statutory health insurance in Germany.This cost-of-illness-study was based on a 6.8% random sample all German people with (4.3 out 70 million people). The healthcare expenses show per capita payer perspective. Healthcare physicians, dentists, pharmacies, hospitals, sick benefits and other were considered. Per costs, cost ratios without as well diabetes-attributable...
Background: Despite the importance of understanding connection between air pollution exposure and diabetes, studies investigating links glucose metabolism in nondiabetic adults are limited. Objective: We aimed to estimate association medium-term exposures with blood glycated hemoglobin A1c (HbA1c) among nondiabetics. Methods: This study included observations from participants (nobs=7,108) population-based Heinz Nixdorf Recall at baseline (2000–2003) follow-up examination (2006–2008). Daily...
ABSTRACT The study aimed to estimate excess mortality in patients aged 60 years or older up 1 year after pelvic fracture compared with a population without fracture. In this retrospective population-based observational study, we use routine data from large health insurance Germany. For each patient first between 2008 and 2010 (n = 5685 cases, 82% female, mean age 80 ± 9 years), about 34 individuals 193,159 controls) were frequency matched by sex, at index date, month. We estimated survival...
Despite clear evidence for the lack of effectiveness and safety, physical restraints are frequently applied in nursing homes. Multicomponent interventions addressing nurses' attitudes organizational culture have been effective reducing restraints.To evaluate two versions a guideline theory-based multicomponent intervention to reduce homes.Pragmatic cluster randomized controlled trial.The study was conducted 120 homes four regions Germany.All residents living participating home during...
The rs738409(G) single nucleotide polymorphism (SNP) in the patatin-like phospholipase domain-containing 3 (PNPLA3) gene associates with increased risk and progression of nonalcoholic fatty liver disease (NAFLD). As recently described severe insulin-resistant diabetes (SIRD) cluster specifically relates to NAFLD, this study examined whether SNP differently hepatic lipid content (hepatocellular lipids [HCL]) insulin sensitivity recent-onset diabetes.A total 917 participants German Diabetes...
A novel clustering approach identified five subgroups of diabetes with distinct progression trajectories complications. We hypothesized that these differ in multiple biomarkers inflammation. Serum levels 74 inflammation were measured 414 individuals recent adult-onset from the German Diabetes Study (GDS) allocated to based on data-driven cluster analysis. Pairwise differences between for assessed generalized linear mixed models before (model 1) and after 2) adjustment variables. Participants...
•Hepatic lipids increase 2-fold in the early course of type 2 diabetes.•Patients with 1 diabetes do not develop steatosis first 5 years after diagnosis.•Adipose tissue mass and insulin resistance drive development steatosis.•Phosphorus metabolites decline due to low portal supply. Background & AimsNon-alcoholic fatty liver disease (NAFLD) is associated abnormal mitochondrial capacity. While oxidative capacity can be increased steatosis, hepatic ATP decreases long-standing diabetes. However,...
Diabetes mellitus (DM) is a major risk factor for complications of pregnancy. Based on information all inpatient births in Germany, we assessed the risks selected pregnancy women with pregestational diabetes (preDM) or gestational (GDM).
Introduction Estimated 50,000 minor children in Germany experience a newly diagnosed cancer one of their parents every year. Family resilience has proven to be an important concept against life crises. However, little research exists regarding family the context parental with children. Based on “Family Resilience Framework,” aim study is investigate processes affected families. In addition, we explore which combinations promoting can characterized. Methods As part mixed-method...
•Care and case management for families with parental cancer underage children such as family-SCOUT is feasible.•Can be implemented in an outreach setting centered on a comprehensive center.•Is significantly associated meaningful reduction of psychosocial distress at the parent level. BackgroundCancer patients minor but also their suffer from significant psychological comorbidity. Protective factors predicting successful coping are well known. Corresponding systematic interventions rare...