A5087716797- Diabetic Foot Ulcer Assessment and Management
- Wound Healing and Treatments
- Pressure Ulcer Prevention and Management
- Infrared Thermography in Medicine
- Pain Management and Treatment
- Botulinum Toxin and Related Neurological Disorders
- Peripheral Artery Disease Management
- Pain Mechanisms and Treatments
- Thermoregulation and physiological responses
- Balance, Gait, and Falls Prevention
- Diagnosis and Treatment of Venous Diseases
- Musculoskeletal pain and rehabilitation
- Bee Products Chemical Analysis
- Surgical site infection prevention
- Surgical Sutures and Adhesives
- Reconstructive Surgery and Microvascular Techniques
- Cerebrovascular and Carotid Artery Diseases
- Streptococcal Infections and Treatments
- Skin Diseases and Diabetes
- Heat Transfer Mechanisms
- Atomic and Subatomic Physics Research
- Tendon Structure and Treatment
- Vascular Procedures and Complications
- Myofascial pain diagnosis and treatment
- Genomics, phytochemicals, and oxidative stress
Nevro (United States)
2021-2025
Baylor College of Medicine
2016
University of Arizona
2008-2015
Hamad Medical Corporation
2012
Rosalind Franklin University of Medicine and Science
2008-2012
Southern Arizona VA Health Care System
2008
Bournemouth University
2006
NHS Grampian
2004
British Nuclear Medicine Society
2004
There is a dearth of long-term data regarding patient and limb survival in patients with diabetic foot ulcers (DFUs). The purpose our study was therefore to prospectively investigate the person DFU during follow-up period more than 10 years.Two hundred forty-seven DFUs without previous major amputation consecutively presenting single diabetes center between June 1998 December 1999 were included this followed up until May 2011. Mean age 68.8 ± 10.9 years, 58.7% male, 55.5% had peripheral...
The high mortality and disability of diabetic nonhealing skin ulcers create an urgent need for the development more efficacious strategies targeting wound healing. In current study, using human clinical specimens, we show that perilesional tissues from patients with diabetes are under severe oxidative stress display higher activation nuclear factor-E2-related factor 2 (NRF2)-mediated antioxidant response than normoglycemic patients. a streptozotocin-induced mouse model, Nrf2(-/-) mice have...
Diabetic foot complications are increasing in prevalence worldwide. Care and attention to these have improved greatly. Many advanced therapies now being investigated or taken through final stages of clinical studies However, the data upon which assumptions regarding morbidity, healing, mortality been based grossly outdated. The purpose this brief article is report on current neuropathic neuroischemic wounds propose that latter category advanced-stage diabetic wound may be emerging as most...
<b><i>Background:</i></b> Individuals with diabetic peripheral neuropathy (DPN) have deficits in sensory and motor skills leading to inadequate proprioceptive feedback, impaired postural balance higher fall risk. <b><i>Objective:</i></b> This study investigated the effect of sensor-based interactive training on stability daily physical activity older adults diabetes. <b><i>Methods:</i></b> Thirty-nine DPN were enrolled...
This study aimed to quantify the impact of an integrated diabetic foot surgical service on outcomes and changes in volume focus.We abstracted registry data from 48 consecutive months at a single institution, evaluating all patients with complications requiring surgery or vascular intervention, compared 24 before after integrating podiatric limb-salvage service.The performed 2923 operations; 790 (27.0%) were related treatment 374 patients. Of these, 502 classified as non-vascular 288...
Objective: The objective was to report patterns of physical activity and their relationship wound healing success in patients with diabetic foot ulcers protected removable or irremovable offloading devices. Methods: Forty-nine people were randomized wear either a cast walker (RCW) an instant total contact (iTCC). Primary outcome measures included change size, activities including position (ie, sitting, standing, lying) locomotion (speed, steps, etc). Outcomes parameters assessed on weekly...
Painful diabetic neuropathy (PDN) can result in the loss of protective sensation, which people are at twice likelihood foot ulceration and three times risk lower extremity amputation. Here, we evaluated long-term effects high-frequency (10 kHz) paresthesia-independent spinal cord stimulation (SCS) on sensation feet associated for individuals with PDN.
The recent SENZA-PDN study showed that high-frequency (10kHz) spinal cord stimulation (SCS) provided significant, durable pain relief for individuals with painful diabetic neuropathy (PDN), along secondary benefits, including improved sleep quality and HRQoL. Given metabolic factors chronic neuropathic are related, we evaluated potential effects of 10kHz SCS on hemoglobin A1c (HbA1c) weight in participants type 2 diabetes (T2D).
Preventing amputations in persons with lower extremity complications of diabetes is a complex endeavor, particularly those concomitant ischemia and tissue loss. Fluorescence angiography (Novadaq SPY system) may provide tool for objective evaluations viability the diabetic foot, which an important indicator ability ulcer to heal adequately. The system uses low-power laser coupled charge-coupled device camera indocyanine green (ICG) sequence perfusion at surface skin. We present illustrated...
Background: Individuals with diabetic peripheral neuropathy frequently experience concomitant impaired proprioception and postural instability. Conventional exercise training has been demonstrated to be effective in improving balance but does not incorporate visual feedback targeting joint perception, which is an integral mechanism that helps compensate for neuropathy. Methods: This prospective cohort study recruited 29 participants (mean ± SD: age, 57 10 years; body mass index [calculated...
Abstract Objective To evaluate the longer‐term efficacy of 10 kHz spinal cord stimulation (SCS) in managing painful diabetic neuropathy (PDN) a routine clinical setting after transition from 24‐month SENZA‐PDN study. Methods We contacted 142 participants who completed 24 months postimplantation follow‐up former randomized controlled trial (SENZA‐PDN). Of these, 57 consented and responded to this post‐study survey. Outcomes assessed included pain relief, health‐related quality life (HRQoL)...
Foot wounds are the most common diabetes-related cause of hospitalization and frequently result in amputation. Although generally diagnosed clinically based on signs symptoms inflammation, empirical antibiotic treatment should be tissue cultures until resolution infection. Advances molecular detection over past decade, including rapid chromogenic agar real-time polymerase chain reaction, have improved diagnostic capabilities. However, chronic may host biofilm bacteria not adequately detected...
Diabetes around the globe results in one major limb amputation every 30 seconds, over 2500 limbs lost per day. The underlying pathophysiology sometimes leads to a chronic Inflammatory stage, which may prevent appropriate healing, and therefore, need for clear strategy assessing classifying wounds wound healing cannot be overstated. Temperature is surrogate marker inflammation. Quantitative thermography using numerical index provides useful way assess healing. Advances technology have...
The objective of this study was to evaluate the 24-month durability pain relief, function, quality life, and safety outcomes for patients with nonsurgical refractory back (NSRBP) treated high-frequency spinal cord stimulation (SCS) within a large, national, multicenter randomized controlled trial (RCT).
Background: Gait-related fall risk is the leading cause of mortality among patients with diabetes, especially those older than 65 years. Deterioration in balance and loss protective sensation lower extremities contribute significantly to diabetic peripheral neuropathy (DPN). This study aimed explore impact foot ulcer on gait. Methods: We recruited 39 participants (age, 56.9 ± 8.2 years; body mass index, 29.6.3 4.7 kg/m 2 ), including 15 DPN without ulcers, 16 8 healthy aged-matched controls....
Abstract The aim of this article was to investigate the effectiveness testing cold immersion recovery responses in diabetic foot with neuropathy using a contact thermography system based on thermochromic liquid crystals. A total 81 subjects no history ulceration were assigned neuropathy, non and healthy groups. Each group received prior verbal written description test objectives subsequently underwent comprehensive care examination. room temperature humidity consistently maintained at 24°C...