A5087193780- Glioma Diagnosis and Treatment
- Neurological disorders and treatments
- Spine and Intervertebral Disc Pathology
- Spinal Fractures and Fixation Techniques
- Parkinson's Disease Mechanisms and Treatments
- Musculoskeletal pain and rehabilitation
- Religion, Society, and Development
- Brain Metastases and Treatment
- Social Capital and Networks
- CNS Lymphoma Diagnosis and Treatment
- Political Economy and Marxism
- Meningioma and schwannoma management
- Management of metastatic bone disease
- Neurosurgical Procedures and Complications
- Botulinum Toxin and Related Neurological Disorders
- Sports Performance and Training
- Sports injuries and prevention
- Transcranial Magnetic Stimulation Studies
- American Constitutional Law and Politics
- Cervical and Thoracic Myelopathy
- Spinal Hematomas and Complications
- Genetic Neurodegenerative Diseases
- Head and Neck Surgical Oncology
- Pain Management and Treatment
- Neurofibromatosis and Schwannoma Cases
Mayo Clinic in Florida
2010-2025
WinnMed
2010-2025
Nottingham University Hospitals NHS Trust
2024-2025
Mayo Clinic in Arizona
2006-2024
Mayo Clinic Hospital
2012-2024
Queen's Medical Centre
2024
Neurological Surgery
2010-2023
University of Limerick
2012-2023
Queen Mary University of London
2023
University Hospital Galway
2008-2022
Object. The authors report a retrospective analysis of 194 patients surgically treated at their institutions for symptomatic lumbar synovial cysts from January 1974 to 1996. Methods. Patient characteristics including age, sex, symptoms, signs, and preoperative neuroimaging studies were reviewed. Surgical procedures, complications, results, pathological findings correlated with assessment. One hundred ninety-four cysts. Eighty percent diagnosed between 1987 There 100 men 94 women an average...
OBJECTIVE Spinal cord stimulation (SCS) at 10 kHz (10-kHz SCS) is a safe and effective therapy for treatment of chronic low-back pain. However, it unclear from existing evidence whether these findings can be generalized to patients with back pain that refractory conventional medical management (CMM) who have no history spine surgery are not acceptable candidates surgery. The authors termed this condition "nonsurgical pain" (NSRBP) conducted multicenter, randomized controlled trial compare...
This analysis was performed to examine the outcome of patients with histologically confirmed central neurocytomas.Thirty-two neurocytomas were evaluated retrospectively. Patients treated various combinations surgery, chemotherapy, and radiotherapy (RT). Follow-up ranged from 2.3 15.3 years (median, 4.7 years).The overall 5-year survival local control rates 81% 79%, respectively. No patient developed metastases. The rate 70% for undergoing subtotal resection (STR) 100% those gross total (GTR)...
BACKGROUND This study examined the outcome of patients with histologically confirmed pineal region tumors. METHODS One hundred thirty-five tumors and other germ cell brain were evaluated retrospectively. The parenchymal (PPTs) included 15 pineoblastomas (PB), 2 mixed PPTs, 4 PPTs intermediate differentiation, 9 pineocytomas. 48 germinomas, 26 tumors, 11 mature teratomas, immature 6 malignant yolk sac 3 choriocarcinomas. Patients treated various combinations chemotherapy, radiotherapy,...
Thirty patients with histologically confirmed posterior fossa ependymomas operated on between January 1976 and December 1988 were reviewed. The median age was 44 years (range, 1-69 yr). There 7 children (aged 5 yr or younger) 23 adults 16 older). 18 female 12 male patients. Headache, nausea vomiting, disequilibrium the most frequent symptoms. common findings ataxia nystagmus. Gross total resection performed in 8 (27%), subtotal 21 (70%), biopsy only 1 patient (3%). Tumors low grade 73% high...
Sampling restrictions have hindered the comprehensive study of invasive non-enhancing (NE) high-grade glioma (HGG) cell populations driving tumor progression. Here, we present an integrated multi-omic analysis spatially matched molecular and multi-parametric magnetic resonance imaging (MRI) profiling across 313 multi-regional biopsies, including 111 from NE, 68 HGG patients. Whole exome RNA sequencing uncover unique genomic alterations to unresectable NE tumor, subclonal events, which inform...
We report on 6 advanced Parkinson's disease (PD) patients who underwent bilateral subthalamic nucleus (STN) deep brain stimulation (DBS) surgery whose restless legs syndrome (RLS) improved postoperatively. Despite a mean 56% decrease in their levodopa equivalents postoperatively, RLS scores dropped by of 84% (100% three). Our findings suggest that STN DBS can improve with PD.
Short-lasting unilateral neuralgiform headache with conjunctival injection and tearing (SUNCT) is a severe primary disorder that often refractory to medical therapy. Although the pathogenesis of this other trigeminal autonomic cephalalgias not completely understood, ipsilateral activation posterior inferior hypothalamus has been identified on functional imaging studies during attacks. The authors report case SUNCT syndrome successfully treated hypothalamic deep brain stimulation discuss...
"Lubag" or X-linked dystonia-parkinsonism (XDP) is a genetic syndrome afflicting Filipino men. Intracranial surgical procedures for Lubag have been unsuccessful. We report 45-year-old male with genetically confirmed XDP who underwent bilateral pallidal deep brain stimulation (DBS) surgery. The patient started to exhibit improvement on initial programming, most notably of his severe jaw-opening dystonia. At 1-year follow-up, Burke-Fahn-Marsden dystonia score and motor Unified Parkinson's...
Introduction: Total hip arthroplasty (THA) is a commonly performed and highly successful surgical procedure. Metal‐on‐metal (MoM) THA implants were introduced two decades ago subsequently recalled due to high early revision rates. Acetabular cup erosion fragmentation secondary chronic edge loading causing delayed instability are rare but devastating complications of MoM warranting expeditious surgery. Case Presentation: We report 70‐year‐old male with history bilateral who presented left...
CIED Clinic Survey | Manuscript•While most respondents were reportedly aware of the 2023 HRS/EHRA/APHRS/LAHRS consensus on management remote device clinics, meaningful disparities found between statement recommendations and reported practices.•Remote monitoring practices more homogeneous in United States with respect to types remotely monitored frequency scheduled transmissions; Europe, much heterogeneity was observed.•Despite low actionability routine office visits for patients CIEDs, 90%...
✓ A prospective study of patients with neurogenic claudication and lumbar spinal stenosis was undertaken to determine whether measurement exercise tolerance on the treadmill would be useful in defining baseline functional status response surgical treatment. Twenty an average age 73 years, all whom had intractable radiographically confirmed severe stenosis, were studied. Lumbar decompressive laminectomy performed patients. Preoperatively 2 months postoperatively, quantitative assessment...
Study Design. A prospective study of exercise tolerance on the treadmill before and after decompressive laminectomy in patients with severe lumbar spinal stenosis. Objectives. To determine whether testing provides useful information about baseline functional status surgical outcome. Summary Background Data. Historically, criteria for selecting surgery assessing postoperative outcome have been variable. Functional has not used a systematic fashion. Methods. Fifty stenosis underwent...
Abstract Background We report the accumulated experience with ventral intermediate nucleus deep brain stimulation for medically refractory orthostatic tremor. Methods Data from 17 patients were reviewed, comparing presurgical, short‐term (0‐48 months), and long‐term (≥48 months) follow‐up. The primary end point was composite activities of daily living/instrumental living score. Secondary points included latency symptoms on standing treatment‐related complications. Results There a 21.6%...
This analysis was performed to determine the clinical outcome of patients with primary nongerminomatous germ cell tumors brain. The efficacy various treatment options evaluated.A total 57 brain were identified. Patient-related data collected and analyzed retrospectively. Follow-up in surviving ranged from 3 243 months (median follow-up 36). Survival failure rates determined using Kaplan-Meier method, differences between survival curves evaluated either log rank test or Wilcoxon test.The...