A5087889585- Air Quality and Health Impacts
- Climate Change and Health Impacts
- Noise Effects and Management
- Childhood Cancer Survivors' Quality of Life
- Family Support in Illness
- Glioma Diagnosis and Treatment
- Gestational Diabetes Research and Management
- Ocular Oncology and Treatments
- Chronic Disease Management Strategies
- Family and Disability Support Research
- Blood Pressure and Hypertension Studies
- Cancer-related Molecular Pathways
- Cardiac, Anesthesia and Surgical Outcomes
- Urban Transport and Accessibility
- Health, Environment, Cognitive Aging
- Bariatric Surgery and Outcomes
- Health, psychology, and well-being
- Obesity and Health Practices
- Cardiovascular Health and Risk Factors
- Sports Science and Education
- Healthcare professionals’ stress and burnout
- Diverse Education Studies and Reforms
- Medical Education and Admissions
- Antiplatelet Therapy and Cardiovascular Diseases
- Cancer survivorship and care
Heinrich Heine University Düsseldorf
2020-2025
Düsseldorf University Hospital
2021-2024
Deutsches Diabetes-Zentrum e.V.
2021-2024
University of Duisburg-Essen
2009-2019
Essen University Hospital
2009-2016
Institut für Medizinische Informatik, Biometrie und Epidemiologie
2009-2016
Heidelberg University
2016
University Hospital Heidelberg
2016
Zimmer Biomet (Germany)
2013
Recent studies have shown an association of short-term exposure to fine particulate matter (PM) with transient increases in blood pressure (BP), but it is unclear whether long-term has effect on arterial BP and hypertension.
Traffic noise affects a large number of people, particularly in urbanized areas. Noise causes stress and annoyance, but less is known about the relationship between depression.We investigated association residential road traffic with depressive symptoms using 5-year follow-up data from German population-based study.We analyzed 3,300 participants Heinz Nixdorf Recall study who were 45 75 years old without at baseline (2000-2003). Depressive defined based on Center for Epidemiologic Studies...
<h3>Background</h3> In several studies, exposure to fine particulate matter (PM) has been associated with inflammation, inconsistent results. We used repeated measurements examine the association of long-term and ultrafine particle blood markers inflammation coagulation. <h3>Methods</h3> baseline (2000–2003) follow-up (2006–2008) data from Heinz Nixdorf Recall Study, a German population-based prospective cohort 4814 participants. A chemistry transport model was applied daily surface...
Abstract Background Survivors of heritable retinoblastoma carry a high risk to develop second cancers. Eye‐preserving radiotherapy raises this risk, while the impact chemotherapy remains less defined. Procedure This population‐based study characterizes all treatment modalities on cancers incidence and type after in Germany. Data cancer 648 patients with treated between 1940 2008 at German national reference center for were analyzed identify associations treatment. Results The cumulative...
•Care and case management for families with parental cancer underage children such as family-SCOUT is feasible.•Can be implemented in an outreach setting centered on a comprehensive center.•Is significantly associated meaningful reduction of psychosocial distress at the parent level. BackgroundCancer patients minor but also their suffer from significant psychological comorbidity. Protective factors predicting successful coping are well known. Corresponding systematic interventions rare...
The majority of studies investigating stress in primary care have focused either on general practitioners (GPs) or practice assistants (PAs), but did not measure a level. We analyzed the prevalence chronic for both professional groups and level investigated personal, practice, regional characteristics.Chronic was measured GPs PAs from 136 German practices using standardized, self-administered TICS-SSCS questionnaire (12 items). Based sum-score, participants per group were categorized as...
Abstract Purpose Single motherhood is associated with increased psychosocial risks, affecting both mothers and their minor children. However, little known about the specific impact of maternal cancer in single (SMs). This study compared psychological burden, quality life, problems, parental concerns between SMs partnered (PMs) affected by caring for Methods Cross-sectional analysis baseline data from a multicenter, non-randomized, controlled trial Germany (Family-SCOUT). PMs were assessed...
Introduction: Parental cancer affects the whole family and can have negative impact on as a system well single members. This multicentre, prospective, interventional non‐randomized family‐SCOUT study aimed to implement comprehensive psychosocial intervention provide support for during after disease. The purpose of this is analyse contextual factors that subjective perceived effectiveness family‐scout families affected by parental from healthy parents’ perspective. Methods: Semi‐structured...
Purpose Intraocular retinoblastoma is curable, but survivors with a heritable predisposition are at high risk for second malignancies. Because malignancies associated mortality, prognostic factors malignancy influence long-term overall survival. This study investigates the impact of all types eye-preserving therapies on survival in complete German cohort patients retinoblastoma. Patients and Methods Overall survival, disease staging using international scales, time period diagnosis,...
Background Children with retinoblastoma carry a high risk to develop second primary malignancies in childhood and adolescence. This study characterizes the type of pediatric after treatment investigates impact different strategies prognostic factors at presentation. Procedure All national patients treated for German referral center current age 6–27 years were invited participate characterize late effects. Results Data on recorded from 488 patients. Ten developed malignancy before 18 years....
Until now, insomnia has not been much of interest in epidemiological neighbourhood studies, although literature provides evidence enough for insomnia-related mechanisms being potentially dependent on contexts. Besides, studies have shown differences sleep along individual social characteristics that might render residents more vulnerable to contextual exposures. Given the role exposure duration and changes relationship between neighbourhoods health, we studied associations unemployment...
Immunization programs are among the most effective public health strategies worldwide. Adequate vaccine storage is a prerequisite to assure vaccines' effectiveness and safety. In questionnaire survey random sample of German primary care physicians, we discovered deficits: 16% physicians had experience with cold chain breaches either as an error or near error, 49 % did not keep temperature log, 21 use separate refrigerator for storage. recent feasibility study practice refrigerators, showed...
Abstract Background Families with minor children affected by parental cancer are at risk of considerable emotional and organizational stress that can severely burden all family members. So far, there has been a lack comprehensive support services for families. The aim this project is to implement evaluate complex psychosocial intervention these families providing advice, information, care on an emotional, psycho-social, communicative level during after the experience across healthcare...
This study aimed to assess the feasibility of a comprehensive psychosocial intervention for families coping with parental cancer.
<h3>Background</h3> A small number of children with unilateral retinoblastoma later develop in the contralateral eye (metachronous bilateral retinoblastoma). <h3>Methods</h3> We analysed clinical and genetic characteristics sporadic to identify risk factors for development metachronous disease. <h3>Results</h3> Fifteen (3.1%) 480 developed (latency period >30 days). The maximum latency was 2.3 years after initial diagnosis. Nine (22.5%) 40 a <i>RB1</i> mutation detectable blood...
The aim of this study was to investigate in a longitudinal approach whether levothyroxine (LT4) substitution has different impact on quality life (QoL) and thyroid related QoL younger (<40 years) older subjects (>60 with elevated thyroid-stimulating hormone (TSH) concentrations. included male female patients newly diagnosed, untreated subclinical hypothyroidism defined by TSH>8 mU/l. Patients were recruited throughout Germany from 2013-2016 evaluated clinical assessment, blood sampling...
Abstract Purpose Within families affected by parental cancer, open communication impacts the well-being of parents and their children; however, limited research exists on patterns in these families. This sub-study addresses this through Family-SCOUT study, a multicenter, prospective, interventional, non-randomized investigation with intervention (IG) control group (CG). The purpose was to identify compare differences between IG CG as part process evaluation. question addressed both groups:...
Introduction Women with gestational diabetes mellitus (GDM) have a higher risk of developing type 2 compared women who never had GDM. Consequently, the question structured aftercare for GDM has emerged. In all probability, many do not receive care according to guidelines. particular, process and interaction between obstetrical, diabetic, gynaecological, paediatric general practitioner lacks clear definitions. Thus, our first goal is analyse current situation in Germany, example,...
Abstract Gestational diabetes mellitus (GDM) is one of the most common medical complications in pregnancy. Information on key figures such as screening rates, prevalence GDM or utilization follow-up care and associated factors varies widely often lacking. The aim our study to provide information rates for well Germany. We used data (2010–2020) from a large, nationwide statutory health insurance containing inpatient outpatient care, including diagnoses, medication treatments. Descriptive...
Studies worldwide show insufficient blood pressure control rates, and effective management of hypertension remains a challenge in general practice. Although structured forms care improved randomized controlled trials, little is known about their effects under routine primary care. This cluster trial (CRT) evaluates the modern interactive medical education series for practitioners on management, including practice redesign strategies. For this CRT, 24 academic teaching practices University...
Background: To improve hypertension control, this cluster randomized trial evaluated the effectiveness of physician manager education about management.Methods: After randomization at practice level, primary care physicians intervention arm, whose practices collaborated with a university department, participated in three-session on evidence-based hypertensiology and implementation strategies.The outcome was blood pressure (BP) control (ambulatory [ABP] <130/80 mmHg) after 5 months.Secondary...
Exposure to family medicine (FM) can serve promote students' interest in this field. This study aimed at identifying clerkship characteristics which decrease or increase FM.This cross-sectional questionnaire analysed evaluations between the years 2004 and 2014. Descriptive statistics were used compare four predefined groups: (1) high FM before after (Remained high), (2) poor low), (3) improved (Increased) (4) decreased (Decreased).Students' of clerkships fourth 6 medical school.All...