Antonio Agudo
- Nutritional Studies and Diet
- Cancer Risks and Factors
- Head and Neck Cancer Studies
- Obesity, Physical Activity, Diet
- Diet and metabolism studies
- Nutrition, Genetics, and Disease
- Nutrition and Health in Aging
- Smoking Behavior and Cessation
- Folate and B Vitamins Research
- Esophageal Cancer Research and Treatment
- Cancer, Lipids, and Metabolism
- Liver Disease Diagnosis and Treatment
- Consumer Attitudes and Food Labeling
- Carcinogens and Genotoxicity Assessment
- Helicobacter pylori-related gastroenterology studies
- Global Cancer Incidence and Screening
- Alcohol Consumption and Health Effects
- RNA modifications and cancer
- Gastric Cancer Management and Outcomes
- Occupational and environmental lung diseases
- Antioxidant Activity and Oxidative Stress
- Air Quality and Health Impacts
- Epigenetics and DNA Methylation
- Genetic Associations and Epidemiology
- Colorectal Cancer Screening and Detection
Institut Català d'Oncologia
2016-2025
Institut d'Investigació Biomédica de Bellvitge
2016-2025
Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública
2010-2024
Bellvitge University Hospital
2007-2024
Institut de Robòtica i Informàtica Industrial
2023
Universitat Politècnica de Catalunya
2023
Hudson Institute
2022
John Wiley & Sons (United States)
2022
Duran i Reynals Hospital
2022
Institut Català d'Ornitologia
2007-2021
Previous studies have relied predominantly on the body-mass index (BMI, weight in kilograms divided by square of height meters) to assess association adiposity with risk death, but few examined whether distribution body fat contributes prediction death.We BMI, waist circumference, and waist-to-hip ratio death among 359,387 participants from nine countries European Prospective Investigation into Cancer Nutrition (EPIC). We used a Cox regression analysis, age as time variable, stratified...
Abstract The European Prospective Investigation into Cancer and Nutrition (EPIC), which covers a large cohort of half million men women from 23 centres in 10 Western countries, was designed to study the relationship between diet risk chronic diseases, particularly cancer. Information on usual individual dietary intake assessed using different validated assessment methods across participating countries. In order adjust for possible systematic over- or underestimation measurements correct...
Dietary factors are thought to have an important role in gastric and esophageal carcinogenesis, but evidence from cohort studies for such a is lacking. We examined the risks of cancer adenocarcinoma associated with meat consumption within European Prospective Investigation Into Cancer Nutrition (EPIC) cohort.A total 521,457 men women aged 35-70 years 10 countries participated EPIC cohort. lifestyle information was collected at recruitment. Cox proportional hazard models were used examine...
It is considered that fruit and vegetable (F&V) protect against oesophagus gastric cancer (GC). However, 2 recent meta-analyses suggest the strength of association on GC seems to be weaker for vegetables than in cohort case-control studies. No evidence exists from studies about adenocarcinoma (ACO). In 521,457 men women participating EPIC 10 European countries, information diet lifestyle was collected at baseline. After an average 6.5 years follow-up, a total 330 65 ACO, confirmed classified...
Background: The higher risk of death resulting from excess adiposity may be attenuated by physical activity (PA). However, the theoretical number deaths reduced eliminating inactivity compared with overall and abdominal obesity remains unclear. Objective: We examined whether modified association between PA all-cause mortality estimated population attributable fraction (PAF) years life gained for these exposures. Design: This was a cohort study in 334,161 European men women. mean follow-up...
No known cohort study has investigated whether the Mediterranean diet can reduce incident coronary heart disease (CHD) events in a population. This examined relation between adherence and risk of CHD 5 Spanish centers European Prospective Investigation into Cancer Nutrition. Analysis included 41,078 participants aged 29-69 years, recruited 1992-1996 followed up until December 2004 (mean follow-up:10.4 years). Confirmed fatal nonfatal were analyzed according to adherence, measured by using an...
Genome-wide association studies (GWAS) have been successful in identifying common genetic variation involved susceptibility to etiologically complex disease. We conducted a GWAS identify upper aero-digestive tract (UADT) cancers. genotyping was carried out using the Illumina HumanHap300 beadchips 2,091 UADT cancer cases and 3,513 controls from two large European multi-centre studies, as well 4,821 generic controls. The 19 top-ranked variants were investigated further an additional 6,514...
<b>Objective</b> To compute the burden of cancer attributable to current and former alcohol consumption in eight European countries based on direct relative risk estimates from a cohort study. <b>Design</b> Combination prospective study with representative population data exposure. <b>Setting </b>Eight (France, Italy, Spain, United Kingdom, Netherlands, Greece, Germany, Denmark) participating Prospective Investigation into Cancer Nutrition (EPIC) <b>Participants</b> 109 118 men 254 870...
Soft drinks are frequently consumed, but whether this consumption is associated with mortality risk unknown and has been understudied in European populations to date.
Epidemiological evidence suggests that the Mediterranean diet (MD) could reduce risk of breast cancer (BC). As from prospective studies remains scarce and conflicting, we investigated association between adherence to MD BC among 335,062 women recruited 1992 2000, in ten European countries, followed for 11 years on average. Adherence was estimated through an adapted relative (arMED) score excluding alcohol. Cox proportional hazards regression models were used while adjusting factors. A total...
Background: The relationship between coffee consumption and mortality in diverse European populations with variable preparation methods is unclear. Objective: To examine whether associated all-cause cause-specific mortality. Design: Prospective cohort study. Setting: 10 countries. Participants: 521 330 persons enrolled EPIC (European Investigation into Cancer Nutrition). Measurements: Hazard ratios (HRs) 95% CIs estimated using multivariable Cox proportional hazards models. association of...
Abstract Objective To investigate the association of plasma vitamin C and carotenoids, as indicators fruit vegetable intake, with risk type 2 diabetes. Design Prospective case-cohort study. Setting Populations from eight European countries. Participants 9754 participants incident diabetes, a subcohort 13 662 individuals Investigation into Cancer Nutrition (EPIC) cohort 340 234 participants: EPIC-InterAct Main outcome measure Incident Results In multivariable adjusted model, higher was...
Leukocyte telomere length (LTL) is a heritable biomarker of genomic aging. In this study, we perform genome-wide meta-analysis LTL by pooling densely genotyped and imputed association results across large-scale European-descent studies including up to 78,592 individuals. We identify 49 regions at false dicovery rate (FDR) < 0.05 threshold prioritize genes 31, with five highlighting nucleotide metabolism as an important regulator LTL. report six significant loci in or near SENP7, MOB1B,...
BackgroundFood processing has been hypothesised to play a role in cancer development; however, data from large-scale epidemiological studies are scarce. This study investigated the association between dietary intake according amount of food and risk at 25 anatomical sites using European Prospective Investigation into Cancer Nutrition (EPIC) study.MethodsThis used prospective EPIC cohort study, which recruited participants March 18, 1991, July 2, 2001, 23 centres ten countries. Participant...