Antonio Agudo

ORCID: 0000-0001-9900-5677
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About
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Research Areas
  • Nutritional Studies and Diet
  • Cancer Risks and Factors
  • Head and Neck Cancer Studies
  • Obesity, Physical Activity, Diet
  • Diet and metabolism studies
  • Nutrition, Genetics, and Disease
  • Nutrition and Health in Aging
  • Smoking Behavior and Cessation
  • Folate and B Vitamins Research
  • Esophageal Cancer Research and Treatment
  • Cancer, Lipids, and Metabolism
  • Liver Disease Diagnosis and Treatment
  • Consumer Attitudes and Food Labeling
  • Carcinogens and Genotoxicity Assessment
  • Helicobacter pylori-related gastroenterology studies
  • Global Cancer Incidence and Screening
  • Alcohol Consumption and Health Effects
  • RNA modifications and cancer
  • Gastric Cancer Management and Outcomes
  • Occupational and environmental lung diseases
  • Antioxidant Activity and Oxidative Stress
  • Air Quality and Health Impacts
  • Epigenetics and DNA Methylation
  • Genetic Associations and Epidemiology
  • Colorectal Cancer Screening and Detection

Institut Català d'Oncologia
2016-2025

Institut d'Investigació Biomédica de Bellvitge
2016-2025

Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública
2010-2024

Bellvitge University Hospital
2007-2024

Institut de Robòtica i Informàtica Industrial
2023

Universitat Politècnica de Catalunya
2023

Hudson Institute
2022

John Wiley & Sons (United States)
2022

Duran i Reynals Hospital
2022

Institut Català d'Ornitologia
2007-2021

Previous studies have relied predominantly on the body-mass index (BMI, weight in kilograms divided by square of height meters) to assess association adiposity with risk death, but few examined whether distribution body fat contributes prediction death.We BMI, waist circumference, and waist-to-hip ratio death among 359,387 participants from nine countries European Prospective Investigation into Cancer Nutrition (EPIC). We used a Cox regression analysis, age as time variable, stratified...

10.1056/nejmoa0801891 article EN New England Journal of Medicine 2008-11-12

10.1038/ng.3002 article EN Nature Genetics 2014-06-01

Abstract The European Prospective Investigation into Cancer and Nutrition (EPIC), which covers a large cohort of half million men women from 23 centres in 10 Western countries, was designed to study the relationship between diet risk chronic diseases, particularly cancer. Information on usual individual dietary intake assessed using different validated assessment methods across participating countries. In order adjust for possible systematic over- or underestimation measurements correct...

10.1079/phn2002395 article EN Public Health Nutrition 2002-12-01

Dietary factors are thought to have an important role in gastric and esophageal carcinogenesis, but evidence from cohort studies for such a is lacking. We examined the risks of cancer adenocarcinoma associated with meat consumption within European Prospective Investigation Into Cancer Nutrition (EPIC) cohort.A total 521,457 men women aged 35-70 years 10 countries participated EPIC cohort. lifestyle information was collected at recruitment. Cox proportional hazard models were used examine...

10.1093/jnci/djj071 article EN JNCI Journal of the National Cancer Institute 2006-02-28

It is considered that fruit and vegetable (F&V) protect against oesophagus gastric cancer (GC). However, 2 recent meta-analyses suggest the strength of association on GC seems to be weaker for vegetables than in cohort case-control studies. No evidence exists from studies about adenocarcinoma (ACO). In 521,457 men women participating EPIC 10 European countries, information diet lifestyle was collected at baseline. After an average 6.5 years follow-up, a total 330 65 ACO, confirmed classified...

10.1002/ijc.21678 article EN International Journal of Cancer 2005-12-27

Background: The higher risk of death resulting from excess adiposity may be attenuated by physical activity (PA). However, the theoretical number deaths reduced eliminating inactivity compared with overall and abdominal obesity remains unclear. Objective: We examined whether modified association between PA all-cause mortality estimated population attributable fraction (PAF) years life gained for these exposures. Design: This was a cohort study in 334,161 European men women. mean follow-up...

10.3945/ajcn.114.100065 article EN cc-by American Journal of Clinical Nutrition 2015-01-15

No known cohort study has investigated whether the Mediterranean diet can reduce incident coronary heart disease (CHD) events in a population. This examined relation between adherence and risk of CHD 5 Spanish centers European Prospective Investigation into Cancer Nutrition. Analysis included 41,078 participants aged 29-69 years, recruited 1992-1996 followed up until December 2004 (mean follow-up:10.4 years). Confirmed fatal nonfatal were analyzed according to adherence, measured by using an...

10.1093/aje/kwp282 article EN American Journal of Epidemiology 2009-11-10
James McKay Thérèse Truong Valérie Gaborieau Amélie Chabrier Shu-Chun Chuang and 95 more Graham Byrnes Давид Заридзе Oxana Shangina Neonila Szeszenia‐Dąbrowska Jolanta Lissowska Péter Rudnai Eleonóra Fabiánová Alexandru Bucur Vladimír Bencko Ivana Holcátová Vladimí­r Janout Lenka Foretová Παγώνα Λάγιου Dimitrios Trichopoulos Simone Benhamou Christine Bouchardy Wolfgang Ahrens Franco Merletti Lorenzo Richiardi Renato Talamini Luigi Barzan Kristina Kjærheim Gary J. Macfarlane Tatiana V. Macfarlane Lorenzo Simonato Cristina Canova Antonio Agudo Xavier Castellsagué Ray Lowry David I. Conway Patricia A. McKinney Claire M. Healy Mary Toner Ariana Znaor María Paula Curado Sérgio Koifman Ana Menezes Victor Wünsch‐Filho José Eluf‐Neto Letícia Fernández Garrote Stefania Boccia Gabriella Cadoni Dario Arzani Andrew F. Olshan Mark C. Weissler William K. Funkhouser Jingchun Luo Jan Lubiński Joanna Trubicka Marcin Lener Dorota Oszutowska–Mazurek Stephen M. Schwartz Chu Chen Sherianne Fish David R. Doody Joshua Muscat Philip Lazarus Carla J. Gallagher Shen-Chih Chang Zuo‐Feng Zhang Qingyi Wei Erich M. Sturgis Li‐E Wang Silvia Franceschi Rolando Herrero Karl T. Kelsey Michael D. McClean Carmen J. Marsit Heather H. Nelson Marjorie Romkes Shama Buch Tomoko Nukui Shilong Zhong Martin Lacko Johannes J. Manni Wilbert H.M. Peters Rayjean J. Hung Esther M. John Lars J. Vatten Inger Njølstad Gary E. Goodman John K. Field Triantafillos Liloglou Paolo Vineis Françoise Clavel‐Chapelon Domenico Palli ­Rosario ­Tumino Vittorio Krogh Salvatore Panico Carlos A. González J. Ramón Quirós Carmen Martı́nez Carmen Navarro Eva Ardanáz Nerea Larrañaga

Genome-wide association studies (GWAS) have been successful in identifying common genetic variation involved susceptibility to etiologically complex disease. We conducted a GWAS identify upper aero-digestive tract (UADT) cancers. genotyping was carried out using the Illumina HumanHap300 beadchips 2,091 UADT cancer cases and 3,513 controls from two large European multi-centre studies, as well 4,821 generic controls. The 19 top-ranked variants were investigated further an additional 6,514...

10.1371/journal.pgen.1001333 article EN cc-by PLoS Genetics 2011-03-17

<b>Objective</b> To compute the burden of cancer attributable to current and former alcohol consumption in eight European countries based on direct relative risk estimates from a cohort study. <b>Design</b> Combination prospective study with representative population data exposure. <b>Setting </b>Eight (France, Italy, Spain, United Kingdom, Netherlands, Greece, Germany, Denmark) participating Prospective Investigation into Cancer Nutrition (EPIC) <b>Participants</b> 109 118 men 254 870...

10.1136/bmj.d1584 article EN cc-by-nc BMJ 2011-04-07

Epidemiological evidence suggests that the Mediterranean diet (MD) could reduce risk of breast cancer (BC). As from prospective studies remains scarce and conflicting, we investigated association between adherence to MD BC among 335,062 women recruited 1992 2000, in ten European countries, followed for 11 years on average. Adherence was estimated through an adapted relative (arMED) score excluding alcohol. Cox proportional hazards regression models were used while adjusting factors. A total...

10.1002/ijc.27958 article EN International Journal of Cancer 2012-11-26

Background: The relationship between coffee consumption and mortality in diverse European populations with variable preparation methods is unclear. Objective: To examine whether associated all-cause cause-specific mortality. Design: Prospective cohort study. Setting: 10 countries. Participants: 521 330 persons enrolled EPIC (European Investigation into Cancer Nutrition). Measurements: Hazard ratios (HRs) 95% CIs estimated using multivariable Cox proportional hazards models. association of...

10.7326/m16-2945 article EN Annals of Internal Medicine 2017-08-15
Chen Li Svetlana Stoma Luca A. Lotta Sophie C. Warner Eva Albrecht and 91 more Alessandra Allione Pascal P. Arp Linda Broer Jessica L. Buxton Alexessander Couto Alves Joris Deelen Iryna O. Fedko Scott D. Gordon Tao Jiang Robert Karlsson Nicola D. Kerrison Taylor K. Loe Massimo Mangino Yuri Milaneschi Benjamin Miraglio Natalia Pervjakova Alessia Russo Ida Surakka Ashley van der Spek Josine E. Verhoeven Najaf Amin Marian Beekman Alexandra I. F. Blakemore Federico Canzian Stephen E. Hamby Jouke‐Jan Hottenga Peter D. Jones Jari Lahti Reedik Mägi Sarah E. Medland Grant W. Montgomery Dale R. Nyholt Markus Perola Kirsi H. Pietiläinen Veikko Salomaa Elina Sillanpää H. Eka D. Suchiman Diana van Heemst Gonneke Willemsen Antonio Agudo Heiner Boeing Dorret I. Boomsma María‐Dolores Chirlaque Guy Fagherazzi Pietro Ferrari Paul W. Franks Christian Gieger Johan G. Eriksson Marc J. Gunter Sara Hägg Iiris Hovatta Liher Imaz Jaakko Kaprio Rudolf Kaaks Timothy J. Key Vittorio Krogh Nicholas G. Martin Olle Melander Andres Metspalu Concha Moreno N. Charlotte Onland‐Moret Peter M. Nilsson Ken K. Ong Kim Overvad Domenico Palli Salvatore Panico Nancy L. Pedersen Brenda W.J.H. Penninx J. Ramón Quirós Marjo‐Riitta Järvelin Miguel Rodríguez‐Barranco Robert A. Scott Gianluca Severi P. Eline Slagboom Tim D. Spector Anne Tjønneland Antonia Trichopoulou ­Rosario ­Tumino André G. Uitterlinden Yvonne T. van der Schouw Cornelia M. van Duijn Elisabete Weiderpass Eros Lazzerini Denchi Giuseppe Matullo Adam S. Butterworth John Danesh Nilesh J. Samani Nicholas J. Wareham Christopher P. Nelson Claudia Langenberg Veryan Codd

Leukocyte telomere length (LTL) is a heritable biomarker of genomic aging. In this study, we perform genome-wide meta-analysis LTL by pooling densely genotyped and imputed association results across large-scale European-descent studies including up to 78,592 individuals. We identify 49 regions at false dicovery rate (FDR) < 0.05 threshold prioritize genes 31, with five highlighting nucleotide metabolism as an important regulator LTL. report six significant loci in or near SENP7, MOB1B,...

10.1016/j.ajhg.2020.02.006 article EN cc-by The American Journal of Human Genetics 2020-02-27

BackgroundFood processing has been hypothesised to play a role in cancer development; however, data from large-scale epidemiological studies are scarce. This study investigated the association between dietary intake according amount of food and risk at 25 anatomical sites using European Prospective Investigation into Cancer Nutrition (EPIC) study.MethodsThis used prospective EPIC cohort study, which recruited participants March 18, 1991, July 2, 2001, 23 centres ten countries. Participant...

10.1016/s2542-5196(23)00021-9 article EN cc-by The Lancet Planetary Health 2023-03-01
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