A5084501683- Nutritional Studies and Diet
- Diet and metabolism studies
- Diet, Metabolism, and Disease
- Consumer Attitudes and Food Labeling
- Biochemical Analysis and Sensing Techniques
- Fibroblast Growth Factor Research
- Nutrition, Genetics, and Disease
- Obesity, Physical Activity, Diet
- Liver Disease Diagnosis and Treatment
- Digestive system and related health
- Agriculture Sustainability and Environmental Impact
- Epigenetics and DNA Methylation
- Advanced Glycation End Products research
- Kruppel-like factors research
- Genetic Syndromes and Imprinting
- Metabolomics and Mass Spectrometry Studies
- Gut microbiota and health
- Genomic variations and chromosomal abnormalities
- Blood Pressure and Hypertension Studies
- Folate and B Vitamins Research
- Water Quality Monitoring Technologies
- Wastewater Treatment and Reuse
- Child Nutrition and Water Access
- Food composition and properties
- Physical Activity and Health
Lund University
2019-2024
Novo Nordisk Foundation
2023-2024
University of Copenhagen
2022-2024
Malmö University
2019
Soft drinks are frequently consumed, but whether this consumption is associated with mortality risk unknown and has been understudied in European populations to date.
Current global food systems threaten human health and environmental sustainability. In 2019, the EAT-Lancet Commission on healthy diets from sustainable defined first reference diet to improve both areas, but there is no consensus how quantify as a index, its relation mortality has not been widely studied.
OBJECTIVE There is sparse evidence for the association of suitable food substitutions red and processed meat on risk type 2 diabetes. We modeled between replacing with other protein sources diabetes estimated its population impact. RESEARCH DESIGN AND METHODS The European Prospective Investigation into Cancer (EPIC)-InterAct case cohort included 11,741 individuals a subcohort 15,450 participants in eight countries. replacement self-reported poultry, fish, eggs, legumes, cheese, cereals,...
It has been suggested that a high intake of sugar or sweeteners may result in an unfavorable microbiota composition; however, evidence is lacking. Hence, this exploratory epidemiological study, we aim to examine if added sugar, sugar-sweetened beverages (SSBs) artificially sweetened (ASBs) associate with the gut composition.Participants (18-70 years) Malmö Offspring Study have provided blood, urine, and fecal samples completed both web-based 4 day food records short frequency questionnaires....
Aims: Although diet is one of the main modifiable risk factors cardiovascular disease, few studies have investigated association between added sugar intake and disease risk. This study aims to investigate associations total sugar, different sugar-sweetened foods beverages, risks stroke, coronary events, atrial fibrillation aortic stenosis. Methods: The population consists 25,877 individuals from Malmö Diet Cancer Study, a Swedish population-based prospective cohort. Dietary data were...
The evidence on the impact of high sugar consumption micronutrient dilution does not yet allow for establishment clear thresholds consumption. To establish upper and lower limit intake added sugar, more studies from different countries multiple populations are needed. aim this study was to examine association between intakes various micronutrients among adult Swedish population across almost two decades.The data were obtained samples populations: 1) Riksmaten Adults, a national dietary...
Abstract Advanced glycation endproducts (AGEs) may contribute to liver carcinogenesis because of their proinflammatory and prooxidative properties. Diet is a major source AGEs, but there sparse human evidence on the role AGEs intake in cancer etiology. We examined association between dietary risk hepatobiliary cancers European Prospective Investigation into Cancer Nutrition prospective cohort (n = 450 111). Dietary three N ε ‐[carboxymethyl]lysine (CML), ‐[1‐carboxyethyl]lysine (CEL) δ...
Background Food biodiversity, encompassing the variety of plants, animals, and other organisms consumed as food drink, has intrinsic potential to underpin diverse, nutritious diets improve Earth system resilience. Dietary species richness (DSR), which is recommended a crosscutting measure been positively associated with micronutrient adequacy in women young children low- middle-income countries (LMICs). However, relationships between DSR major health outcomes have yet be assessed any...
It has been suggested that high intake of added sugar and sugar-sweetened beverages (SSBs) increase the level circulating inflammatory proteins chronic inflammation plays a role in type 2 diabetes (T2D) development. We aim to examine how SSB associate with 136 measured plasma C-reactive protein (CRP) Malmö Diet Cancer–Cardiovascular Cohort (n = 4382), if identified sugar- SSB-associated T2D incidence. A two-step iterative resampling approach was used internally replicate associated intake....
Studies on sugar intake and its link to cardiometabolic risk show inconsistent results, partly due dietary misreporting. Cost-effective easily measured nutritional biomarkers that can complement data are warranted. Measurement of 24-hour urinary sugars is a biomarker intake, but there knowledge gaps regarding the use overnight urine samples. We aim compare 1) sucrose fructose with liquid chromatography-tandem mass spectrometry, 2) self-reported web-based 4-day food records, 3) their...
Abstract Background: Renal cell carcinoma (RCC) accounts for more than 80% of kidney cancers in adults, and obesity is a known risk factor. Regular consumption sweetened beverages has been linked to several chronic diseases, including some types cancer. It uncertain whether soft drink juice associated with RCC. We investigated the associations RCC incidence mortality European Prospective Investigation into Cancer Nutrition (EPIC). Methods: A total 389,220 EPIC participants median age 52...
Background and aimsThis study aimed to expand the European Prospective Investigation into Cancer Nutrition (EPIC) nutrient database (ENDB) by adding amino acid (AA) values, using U.S. (USNDB). Additionally, we evaluate these new protein AA intake estimates from EPIC dietary questionnaires (DQ) 24-h recalls (24-HDR) different matching procedures.Methods resultsDietary energy, intakes were assessed via DQ 24-HDR with USNDB food composition table. Energy calculated compared those ENDB, that...
Biological mechanisms to promote dietary balance remain unclear. Fibroblast growth factor 21 (FGF21) has been suggested contribute such potential regulation considering that FGF21
Abstract Dietary carbohydrates have long been expected to be associated with risk of type 2 diabetes; however, the associations for many and carbohydrate-rich foods remain inconclusive. This study analysed between intakes six types thirteen incident diabetes in 26 622 participants (61 % women) Malmö Diet Cancer Study southern Sweden. intake was assessed at baseline (1991–1996) by using a modified diet history method. During mean follow-up 18 years, 4046 cases were identified. Adjusting...
Hereditary mechanisms are partially responsible for individual differences in sensitivity to and the preference sweet taste. The primary aim of this study was examine associations between 10 genetic variants intake total sugar, added sugars with taste (i.e., monosaccharides sucrose) a middle-aged Swedish population. Two single nucleotide polymorphisms (SNPs) within Fibroblast grow factor 21 (FGF21) gene, seven top hits from genome-wide association (GWAS) on sugar intake, one SNP fat mass...
The adverse health effects of sugar-sweetened beverage intake are well-established, but the implications overall added sugar remain unclear. We investigated associations between and various foods beverages risk 7 cardiovascular diseases in 69,705 participants aged 45-83 years (47.2% female) from Swedish Mammography cohort Cohort men.
The association between leisure-time physical activity and cardiovascular mortality has been previously studied, but few studies have focused on specific activities intensities.The different was investigated among 25,876 individuals without diabetes or disease from the population-based Malmö Diet Cancer Study cohort. estimated average duration spent 17 at baseline in 1991-1996 after 5 years. Cardiovascular obtained a register during mean of 20 years follow-up.A total 15-25 metabolic...
Irregular dietary intakes impairs estimations from food records. Biomarkers and method combinations can be used to improve estimates. Our aim was examine reproducibility two assessment methods, compare them, validate against objective biomarkers. We the Malmö Offspring Study (55% women, 18-71 y) with data a 4-day record (4DFR) short frequency questionnaire (SFFQ) (1) repeated (n = 180), (2) 4DFR SFFQ 1601), (3) of fatty fish, fruits vegetables, citrus plasma biomarkers 1433)...
Abstract Background Copy number (CN) variation (CNV) of the salivary amylase gene ( AMY1 ) influences ability to digest starch and may influence glucose homeostasis, obesity gut microbiota composition. Hence, aim was examine association CNV with fasting glucose, BMI, composition considering habitual intake investigate effect on postprandial response after two different doses. Methods The Malmö Offspring Study n = 1764, 18–71 years) used assess interaction effects between (genotyped by...
Abstract Background About one in ten adults are living with diabetes worldwide. Intake of carbohydrates and carbohydrate-rich foods often identified as modifiable risk factors for incident type 2 diabetes. However, strong correlation between food variables can make it difficult to identify true associations. The purpose this study was clusters analyse their associations incidence the Malmö Diet Cancer Study cohort southern Sweden. Methods Dietary intake 26 622 participants assessed using a...
Abstract Objective To characterise the role of Sucrase-isomaltase (SI) in regulating dietary behaviours, such as sweet preference and food liking Si knockout (Sis-KO) mice population-based cohorts from Greenland UK. Design We profiled appetitive post-ingestive response to carbohydrates SI mice. Alongside this, we conducted detailed analysis 45 foods two Greenlandic (IHIT, n=2778 68 foods, B2018, n=2203 foods) with presence a common (allele frequency = 14.3%) Loss function (LoF) variant,...