Isabel Drake
A5060923359- Nutritional Studies and Diet
- Diet and metabolism studies
- Cancer Risks and Factors
- Nutrition, Genetics, and Disease
- Obesity, Physical Activity, Diet
- Diet, Metabolism, and Disease
- Cancer, Lipids, and Metabolism
- Consumer Attitudes and Food Labeling
- Folate and B Vitamins Research
- Nutrition and Health in Aging
- Metabolism, Diabetes, and Cancer
- Colorectal Cancer Screening and Detection
- Alcohol Consumption and Health Effects
- Liver Disease Diagnosis and Treatment
- Phytoestrogen effects and research
- Genetic Associations and Epidemiology
- Agriculture Sustainability and Environmental Impact
- Biochemical Analysis and Sensing Techniques
- Trace Elements in Health
- Cardiovascular Disease and Adiposity
- Food composition and properties
- Iron Metabolism and Disorders
- Allergic Rhinitis and Sensitization
- Physical Activity and Health
- Cardiovascular Health and Risk Factors
Lund University
2016-2025
Skåne University Hospital
2011-2025
Malmö University
2018-2023
Harvard University
2020
Qatar University
2020
Massachusetts General Hospital
2017-2020
Broad Institute
2020
University of Helsinki
2013
Clinical Science Institute
2011
Cambridge University Press
2011
Both genetic and lifestyle factors contribute to individual-level risk of coronary artery disease. The extent which increased can be offset by a healthy is unknown.
Recently, some US cohorts have shown a moderate association between red and processed meat consumption mortality supporting the results of previous studies among vegetarians. The aim this study was to examine meat, poultry with risk early death in European Prospective Investigation into Cancer Nutrition (EPIC).Included analysis were 448,568 men women without prevalent cancer, stroke, or myocardial infarction, complete information on diet, smoking, physical activity body mass index, who 35 69...
Current global food systems threaten human health and environmental sustainability. In 2019, the EAT-Lancet Commission on healthy diets from sustainable defined first reference diet to improve both areas, but there is no consensus how quantify as a index, its relation mortality has not been widely studied.
Nutrients and other bioactive constituents of foods may interact with each the surrounding food matrix in complex ways. Therefore, associations between single nutrients chronic disease be difficult to identify interpret, but when dietary patterns (DPs) are examined combination many factors will considered. An explorative literature search published review articles was conducted obtain a fuller understanding current DPs epidemiological research, discuss pros cons nutrition results studies...
Abstract Objective To examine how different scoring models for a diet quality index influence associations with mortality outcomes. Design A study within the Malmö Diet and Cancer cohort. Food nutrient intakes were estimated using history method. The included six components: SFA, PUFA, fish shellfish, fibre, fruit vegetables, sucrose. Component scores assigned predefined (based on dietary recommendations) population-based cut-offs median or quintile intakes). Multivariate Cox regression was...
Abstract The aim of this study was to derive dietary patterns associated with cardio-metabolic traits and examine whether these predict prospective changes in incidence the metabolic syndrome (iMetS). Subjects from Malmö Diet Cancer Study cardiovascular cohort without disease related drug treatments at baseline ( n 4071; aged 45–67 years, 40 % men) were included. We applied reduced rank regression on thirty-eight foods that explain variation response variables measured (waist circumference,...
To determine the relationship of a genome-wide polygenic score for coronary artery disease (GPSCAD) with lifetime trajectories CAD risk, directly compare its predictive capacity to traditional risk factors, and assess interplay Pooled Cohort Equations (PCE) clinical estimator. Approach Results: We studied GPSCAD in 28 556 middle-aged participants Malmö Diet Cancer Study, whom 4122 (14.4%) developed over median follow-up 21.3 years. A pronounced gradient was observed-16% those lowest decile...
Nutrition and lifestyle have been long established as risk factors for colorectal cancer (CRC). Modifiable behaviours bear potential to minimize long-term CRC risk; however, translation of information into individualized assessment has not implemented. Lifestyle-based models may aid the identification high-risk individuals, guide referral screening motivate behaviour change. We therefore developed validated a lifestyle-based prediction algorithm in an asymptomatic European population.
The present study aims to describe accelerometer-assessed physical activity (PA) patterns and fulfillment of PA recommendations in a large sample middle-aged men women, differences between subgroups socio-demographic, socio-economic, lifestyle-related variables. A total 27 890 (92.5% participants, 52% aged 50-64 years) women with at least four days valid hip-worn accelerometer data (Actigraph GT3X+, wGT3X+ wGT3X-BT) from the Swedish CArdioPulmonary bioImage Study, SCAPIS, were included. In...
Flavonols, flavanones and flavones (FLAV) are sub-classes of flavonoids that exert cardioprotective anti-carcinogenic properties in vitro vivo . We aimed to estimate the FLAV dietary intake, their food sources associated lifestyle factors ten European countries participating Prospective Investigation into Cancer Nutrition (EPIC) study. intake for 36 037 subjects, aged between 35 74 years, twenty-seven study centres were obtained using standardised 24 h recall software (EPIC-SOFT). An ad hoc...
Abstract Objective To characterize meal patterns across ten European countries participating in the Prospective Investigation into Cancer and Nutrition (EPIC) calibration study. Design Cross-sectional study utilizing dietary data collected through a standardized 24 h diet recall during 1995–2000. Eleven predefined intake occasions period were assessed interview. In present descriptive report, analysed terms of daily number occasions, proportion reporting each occasion energy contributions...
There is uncertainty about the direction and magnitude of associations between parity, breastfeeding risk coronary heart disease (CHD). We examined separate combined parity practices with incidence CHD later in life among women a large, pan-European cohort study.
Importance Prostate cancer, a leading cause of cancer death among men, urgently requires new prevention strategies, which may involve targeting men with an underlying genetic susceptibility. Objective To explore differences in risk early prostate higher vs lower to inform efforts. Design, Setting, and Participants This cohort study used combined analysis genotyped without at inclusion lifestyle data 2 prospective studies Sweden the US, Malmö Diet Cancer Study (MDCS) Health Professionals...
Background The effect of the macronutrient composition usual diet on long term weight maintenance remains controversial. Methods 373,803 subjects aged 25–70 years were recruited in 10 European countries (1992–2000) PANACEA project EPIC cohort. Diet was assessed at baseline using country-specific validated questionnaires and height measured self-reported follow-up most centers. association between change after 5 iso-energetic replacement 5% energy from one by another multivariate linear...
Background The aim of the study was to examine associations between intake macronutrients and dietary fiber incident ischemic cardiovascular disease (iCVD) in men women. Methods We used data from 8,139 male 12,535 female participants (aged 44–73 y) Swedish population-based Malmö Diet Cancer cohort. were without history CVD diabetes mellitus, had reported stable habits questionnaire. assessed by a validated modified diet method, combining 7-d registration cooked meals cold beverages, 168-item...
Fruit and vegetable (F&V) intake is considered as probably protective against overall cancer risk, but results in previous studies are not consistent for thyroid (TC). The purpose of this study to examine the association between consumption fruits, vegetables, fruit juices differentiated risk within European Prospective Investigation into Cancer Nutrition (EPIC) study. EPIC a cohort including over half million participants, recruited 1991 2000. During mean follow‐up 14 years, 748...
Emerging evidence suggests that a metabolic profile associated with obesity may be more relevant risk factor for some cancers than adiposity per se . Basal rate (BMR) is an indicator of overall body metabolism and proxy the impact specific on cancer risk. Therefore, we investigated association predicted BMR incidence 13 obesity‐related in European Prospective Investigation into Cancer Nutrition (EPIC). at baseline was calculated using WHO/FAO/UNU equations relationships between were...