Laudina Rodríguez
A5112135015- Nutritional Studies and Diet
- Estrogen and related hormone effects
- Cancer Risks and Factors
- Colorectal Cancer Screening and Detection
- Obesity, Physical Activity, Diet
- Cancer, Lipids, and Metabolism
- Growth Hormone and Insulin-like Growth Factors
- Smoking Behavior and Cessation
- Prostate Cancer Treatment and Research
- Metabolism, Diabetes, and Cancer
- Diet and metabolism studies
- Bladder and Urothelial Cancer Treatments
- RNA modifications and cancer
- Folate and B Vitamins Research
- Nutrition, Genetics, and Disease
- Hormonal and reproductive studies
- Air Quality and Health Impacts
- Nutrition and Health in Aging
- Pancreatic and Hepatic Oncology Research
- Diet, Metabolism, and Disease
- Ovarian cancer diagnosis and treatment
- Endometrial and Cervical Cancer Treatments
- Glioma Diagnosis and Treatment
- Toxic Organic Pollutants Impact
- Global Cancer Incidence and Screening
Universidad Estatal del Sur de Manabi
2025
Pontificia Universidad Católica del Ecuador
2024
Gobierno del Principado de Asturias
2009-2013
Danish Cancer Society
2010-2012
Imperial College London
2010-2012
Heidelberg University
2010-2012
University Hospital Heidelberg
2010-2012
Aarhus University Hospital
2010-2012
Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública
2010-2012
Directorate of Health
2008-2011
It is widely believed that cancer can be prevented by high intake of fruits and vegetables. However, inconsistent results from many studies have not been able to conclusively establish an inverse association between fruit vegetable overall risk.We conducted a prospective analysis the European Prospective Investigation into Cancer Nutrition (EPIC) cohort assess relationships total fruits, vegetables, vegetables combined risk during 1992-2000. Detailed information on dietary habit lifestyle...
Abstract Cigarette smoking is an established risk factor for pancreatic cancer. However, prospective data most European countries are lacking, and epidemiologic studies on exposure to environmental tobacco smoke (ETS) in relation cancer scarce. We examined the association of cigarette ETS with within Prospective Investigation into Cancer Nutrition (EPIC). This analysis was based 465,910 participants, including 524 first incident cases diagnosed after a median follow‐up 8.9 years. Estimates...
Abstract Circulating concentrations of insulin-like growth factor I (IGF-I) and IGF binding proteins (IGFBP) have been associated with the risk several types cancer. Dietary correlates IGF-I IGFBPs are not yet well established. The objective this study was to assess association between dietary intake serum IGF-I, IGFBP-1, IGFBP-2, IGFBP-3 in a cross-sectional analysis 4,731 men women taking part European Prospective Investigation into Cancer Nutrition. Diet assessed using country-specific...
Metabolic syndrome (MetS) is purportedly related to risk of developing colorectal cancer; however, the association MetS, as defined according recent international criteria, and cancer has not been yet evaluated. In particular, it remains unclear what extent MetS components individually account for such an association. We addressed these issues in a nested case-control study that included 1,093 incident cases matched (1:1) controls by using incidence density sampling. Conditional logistic...
Menopausal hormone therapy (MHT) is characterized by use of different constituents, regimens and routes administration. We investigated the association between types MHT breast cancer risk in EPIC cohort study. The analysis based on data from 133,744 postmenopausal women. Approximately women contributed to this analysis. Information was derived country-specific self-administered questionnaires with a single baseline assessment. Incident cancers were identified through population registries...
Abstract Background: The etiologies of glioma and meningioma tumors are largely unknown. Although reproductive hormones thought to influence the risk these tumors, epidemiologic data not supportive this hypothesis; however, few cohort studies have published on topic. We examined relation between factors among women in European Prospective Investigation into Cancer Nutrition (EPIC). Methods: After a mean 8.4 years follow-up, 193 194 cases were identified 276,212 women. Information hormone use...
Prediagnostic endogenous sex steroid hormone levels have well established associations with overall risk of breast cancer. While evidence toward the existence distinct subtypes cancer accumulates, few studies investigated receptor [estrogen (ER) and/or progesterone (PR)] defined In a case-control study nested within EPIC cohort (European Prospective Investigation into Cancer and Nutrition), estradiol, testosterone, hormone-binding globulin were measured in prediagnostic serum samples from...
Results from case-control and prospective studies suggest a moderate positive association between obesity height differentiated thyroid carcinoma (TC). Little is known on the relationship other measures of adiposity TC risk. Here, we present results study body size risk based large European (EPIC). During follow-up, 508 incident cases were identified in women, 58 men. 78% papillary TC. Cox proportional hazard models used to estimate ratios (HRs). In was significantly associated with mass...
Risk models for lung cancer incidence would be useful prioritizing individuals screening and participation in clinical trials of chemoprevention. We present a risk model built using prospective cohort data from general population which predicts individual given time period. build separate current former smokers 169,035 ever the multicenter European Prospective Investigation into Cancer Nutrition (EPIC) considered never smokers. The set was split independent training test sets. Lung modeled...
Phytosterol intake with natural foods, a measure of healthy dietary choices, increases plasma levels, but increased phytosterols are believed to be coronary heart disease (CHD) risk factor. To address this paradox, we evaluated baseline factors, phytosterol intake, and noncholesterol sterol levels in participants case control study nested within the European Prospective Investigation into Cancer Nutrition (EPIC) Spanish cohort who developed CHD (n = 299) matched controls 584) remained free...
Abstract Background To examine the association of education with body mass index (BMI) and waist circumference (WC) in European Prospective Investigation into Cancer Nutrition (EPIC). Method This study included 141,230 male 336,637 female EPIC-participants, who were recruited between 1992 2000. Education, which was assessed by questionnaire, classified four categories; BMI WC, measured trained personnel most participating centers, modeled as continuous dependent variables. Associations...
Background: Height and BMI are risk factors for several types of cancer may be related to circulating concentrations insulin-like growth factor-I (IGF-I), a peptide associated with increased risk.Aim: To assess the associations between height, serum IGF-I IGF binding protein (IGFBP)-1, -2 -3.Subjects methods: This cross-sectional analysis included 1142 men 3589 women aged 32–77 years from multi-centre study, European Prospective Investigation Cancer Nutrition (EPIC).Results: In men, there...
Abstract Background: A potential dual role of folate in colorectal cancer (CRC) is currently subject to debate. We investigate the associations between plasma folate, several relevant folate-related polymorphisms, and CRC risk within large European Prospective Investigation into Cancer Nutrition cohort. Methods: In this nested case-control study, 1,367 incident cases were matched 2,325 controls for study center, age, sex. Risk ratios (RR) estimated with conditional logistic regression...
The mTOR (mammalian target of rapamycin) signal transduction pathway integrates various signals, regulating ribosome biogenesis and protein synthesis as a function available energy amino acids, assuring an appropriate coupling cellular proliferation with increases in cell size. In addition, recent evidence has pointed to interplay between the p53 pathways. We investigated genetic variability 67 key genes which interact mTOR. tested association 1,084 tagging SNPs prostate cancer risk study...