Kay‐Tee Khaw
- Nutritional Studies and Diet
- Genetic Associations and Epidemiology
- Cancer Risks and Factors
- Cancer, Lipids, and Metabolism
- Obesity, Physical Activity, Diet
- Nutrition and Health in Aging
- Bone health and osteoporosis research
- Nutrition, Genetics, and Disease
- Liver Disease Diagnosis and Treatment
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Vitamin D Research Studies
- Lipoproteins and Cardiovascular Health
- Diet and metabolism studies
- Estrogen and related hormone effects
- Health disparities and outcomes
- Epigenetics and DNA Methylation
- Fatty Acid Research and Health
- Colorectal Cancer Screening and Detection
- Pancreatic and Hepatic Oncology Research
- Growth Hormone and Insulin-like Growth Factors
- Blood Pressure and Hypertension Studies
- Physical Activity and Health
- Adipokines, Inflammation, and Metabolic Diseases
- Vitamin C and Antioxidants Research
- Folate and B Vitamins Research
University of Cambridge
2015-2024
Medical Research Council
2010-2024
University College London
2008-2024
MRC Epidemiology Unit
2013-2024
Moorfields Eye Hospital NHS Foundation Trust
2020-2024
MRC Biostatistics Unit
1989-2023
Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública
2010-2023
University of Balamand
2018-2023
Antonine University
2023
Bridge University
2003-2022
Previous studies have relied predominantly on the body-mass index (BMI, weight in kilograms divided by square of height meters) to assess association adiposity with risk death, but few examined whether distribution body fat contributes prediction death.We BMI, waist circumference, and waist-to-hip ratio death among 359,387 participants from nine countries European Prospective Investigation into Cancer Nutrition (EPIC). We used a Cox regression analysis, age as time variable, stratified...
Leisure-time physical activity has been associated with lower risk of heart-disease and all-cause mortality, but its association cancer is not well understood.
Context-Data regarding the association between subclinical hypothyroidism and cardiovascular disease outcomes are conflicting among large prospective cohort studies.This might reflect differences in participants' age, sex, thyroid-stimulating hormone (TSH) levels, or preexisting disease.Objective-To assess risks of coronary heart (CHD) total mortality for adults with hypothyroidism. Data Sources StudySelection-The databases MEDLINE EMBASE (1950 to May 31, 2010) were searched without language...
There is debate about the value of assessing levels C-reactive protein (CRP) and other biomarkers inflammation for prediction first cardiovascular events.We analyzed data from 52 prospective studies that included 246,669 participants without a history disease to investigate adding CRP or fibrinogen conventional risk factors risk. We calculated measures discrimination reclassification during follow-up modeled clinical implications initiation statin therapy after assessment fibrinogen.The...
Background: Increasing evidence suggests a continuous relationship between blood glucose concentrations and cardiovascular risk, even below diagnostic threshold levels for diabetes. Objective: To examine the hemoglobin A1c, disease, total mortality. Design: Prospective population study. Setting: Norfolk, United Kingdom. Participants: 4662 men 5570 women who were 45 to 79 years of age residents Norfolk. Measurements: Hemoglobin A1c disease risk factors assessed from 1995 1997, events...
Current evidence suggests that high red meat intake is associated with increased colorectal cancer risk. High fish may be a decreased risk, but the existing less convincing.
There is overwhelming evidence that behavioural factors influence health, but their combined impact on the general population less well documented. We aimed to quantify potential of four health behaviours mortality in men and women living community.We examined prospective relationship between lifestyle a study 20,244 aged 45-79 y with no known cardiovascular disease or cancer at baseline survey 1993-1997, community United Kingdom, followed up 2006. Participants scored one point for each...
<h3>Abstract</h3> <b>Objective</b> To examine whether adherence to the modified Mediterranean diet, in which unsaturates were substituted for monounsaturates, is associated with longer life expectancy among elderly Europeans. <b>Design</b> Multicentre, prospective cohort study. <b>Setting</b> Nine European countries (Denmark, France, Germany, Greece, Italy, Netherlands, Spain, Sweden, United Kingdom). <b>Participants</b> 74 607 men and women, aged 60 or more, without coronary heart disease,...
Women ( n 160) aged 50 to 65 years were asked weigh their food for 4 d on four occasions over the period of 1 year, using PETRA (Portable Electronic Tape Recorded Automatic) scales. Throughout they complete seven other dietary assessment methods: a simple 24 h recall, structured recall with portion size assessments photographs, two food-frequency questionnaires, 7 estimated record or open-ended diary, (menu) record, and sizes assessed photographs. Comparisons between average 16 weighed...
Background— The relation between endogenous testosterone concentrations and health in men is controversial. Methods Results— We examined the prospective relationship mortality due to all causes, cardiovascular disease, cancer a nested case-control study based on 11 606 aged 40 79 years surveyed 1993 1997 followed up 2003. Among those without prevalent or 825 who subsequently died were compared with control group of 1489 still alive, matched for age date baseline visit. Endogenous at...
It has been postulated that dehydroepiandrosterone (DHEA) and its sulfate ester, (DHEAS), the major secretory products of human adrenal gland, may be discriminators life expectancy aging. We examined relation base-line circulating DHEAS levels to subsequent 12-year mortality from any cause, cardiovascular disease, ischemic heart disease in a population-based cohort 242 men aged 50 79 years at start study. Mean decreased with age were also significantly lower history than those without such...