Teresa Ferreira
- Genetic Associations and Epidemiology
- Genetic Mapping and Diversity in Plants and Animals
- Nutrition, Genetics, and Disease
- Thyroid Cancer Diagnosis and Treatment
- Genetic and phenotypic traits in livestock
- Cardiovascular Function and Risk Factors
- Hemoglobinopathies and Related Disorders
- Cardiomyopathy and Myosin Studies
- Bioinformatics and Genomic Networks
- Iron Metabolism and Disorders
- Birth, Development, and Health
- Epigenetics and DNA Methylation
- Cardiovascular Disease and Adiposity
- BRCA gene mutations in cancer
- Adipose Tissue and Metabolism
- RNA modifications and cancer
- Cancer-related molecular mechanisms research
- DNA Repair Mechanisms
- Growth Hormone and Insulin-like Growth Factors
- Lipoproteins and Cardiovascular Health
- Liver Disease Diagnosis and Treatment
- Ovarian function and disorders
- Neuroendocrine Tumor Research Advances
- Pancreatic function and diabetes
- Prenatal Screening and Diagnostics
University of Oxford
2014-2024
Hospital Prof. Dr. Fernando Fonseca
2014-2024
Instituto Português de Oncologia Francisco Gentil
2002-2024
Hospital de Clínicas
2024
Open Data Institute
2021-2024
Goa Medical College
2020-2023
Centro Hospitalar do Baixo Vouga
2023
Centre for Human Genetics
2011-2022
Weatherford College
2022
Banaras Hindu University
2022
To characterize type 2 diabetes (T2D)-associated variation across the allele frequency spectrum, we conducted a meta-analysis of genome-wide association data from 26,676 T2D case and 132,532 control subjects European ancestry after imputation using 1000 Genomes multiethnic reference panel. Promising signals were followed up in additional sets (of 14,545 or 7,397 38,994 71,604 subjects). We identified 13 novel T2D-associated loci (P < 5 × 10-8), including variants near GLP2R, GIP, HLA-DQA1...
A scavenger that protects the heart Coronary disease is a tale of two forms plasma cholesterol. In contrast to well-established effects “bad” cholesterol (LDL-C), role “good” (HDL-C) mysterious. Elevated HDL-C correlates with lower risk disease, yet drugs raise levels do not reduce risk. Zanoni et al. found some people exceptionally high carry rare sequence variant in gene encoding major receptor, receptor BI. This destroys receptor's ability take up HDL-C. Interestingly, this have higher...
Common single-nucleotide polymorphisms (SNPs) are predicted to collectively explain 40-50% of phenotypic variation in human height, but identifying the specific variants and associated regions requires huge sample sizes
Given the anthropometric differences between men and women previous evidence of sex-difference in genetic effects, we conducted a genome-wide search for sexually dimorphic associations with height, weight, body mass index, waist circumference, hip waist-to-hip-ratio (133,723 individuals) took forward 348 SNPs into follow-up (additional 137,052 total 94 studies. Seven loci displayed significant (FDR<5%), including four previously established (near GRB14/COBLL1, LYPLAL1/SLC30A10, VEGFA,...