A5034712398- Diabetes Management and Research
- Diabetes Treatment and Management
- Diabetes and associated disorders
- Genetic Associations and Epidemiology
- Metabolism, Diabetes, and Cancer
- Cancer Risks and Factors
- Bioinformatics and Genomic Networks
- Pancreatic function and diabetes
- Retinal Diseases and Treatments
- Regulation of Appetite and Obesity
- Breast Cancer Treatment Studies
- Genetic Mapping and Diversity in Plants and Animals
- Growth Hormone and Insulin-like Growth Factors
- Diet, Metabolism, and Disease
- Liver Disease Diagnosis and Treatment
- Cardiovascular Function and Risk Factors
- Retinal Imaging and Analysis
- Cardiac Valve Diseases and Treatments
- Biochemical Analysis and Sensing Techniques
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Breast Lesions and Carcinomas
- Neuroblastoma Research and Treatments
- Diet and metabolism studies
- Machine Learning in Bioinformatics
Smartfish (Norway)
2020
Lund University
2007-2019
Skåne University Hospital
2012-2018
Novo Nordisk (Denmark)
2018
Karolinska Institutet
2017
University of Malaya
2017
Scania (Sweden)
2012-2014
Malmö University
2006-2014
Genomics (United Kingdom)
2008-2010
Diabetes Australia
2008-2010
Objective Sweetened beverage intake is associated with increased risk of type 2 diabetes, but its association autoimmune diabetes unclear. We aimed to investigate sweetened and latent in adults (LADA); features diabetes. Design/methods Data from a Swedish population-based study was used, including incident cases LADA ( n = 357) 1136) randomly selected controls 1371). Diabetes classification based on onset age (≥35), glutamic acid decarboxylase autoantibodies (GADA) C-peptide. information...
It is known that narrowband ultraviolet B (NB-UVB) radiation and oral vitamin D(3) supplementation can both improve serum levels of D, expressed as 25-hydroxyvitamin [25(OH)D(3) ]. However, surprisingly few studies have compared the effects two interventions in treating D deficiency.To compare effect NB-UVB exposure with on patients deficiency.Seventy-three participants deficiency ≤ 25 nmol L(-1) ] were consecutively enrolled from February 2010 to May 2011, avoiding summer period (June...
Changes in eye protrusion patients treated with pioglitazone.Open-label prospective.Thirty-six type 2 diabetes and HbA1c >or= 6.5% were included a study where pioglitazone was added to current therapy metformin sulphonylurea.The degree of before 26 weeks after treatment measured using Krahn's exophthalmometer.Thirteen (group A) exhibited an increase mm 23 B) < (P (between groups) = 0.036). Patients group A vs. B had the same BMI, mean doses pioglitazone, but lower levels (mean +/- SD)...
Objective Moderate alcohol consumption is associated with a reduced risk of type 2 diabetes. Our aim was to investigate whether the latent autoimmune diabetes in adults (LADA), an form features Design A population-based case–control study carried out association and LADA. Methods We used data from ESTRID between 2010 2013, including 250 incident cases LADA (glutamic acid decarboxylase antibodies (GADAs) positive) 764 (GADA negative), 1012 randomly selected controls aged ≥35. Logistic...
It has been suggested that intake of fatty fish may protect against both type 1 and 2 diabetes. Hypotheses rest on the high marine omega-3 acid eicosapentaenoic acid+docosahexaenoic (EPA+DHA) vitamin D contents, with possible beneficial effects immune function glucose metabolism. Our aim was to investigate, for first time, consumption in relation risk latent autoimmune diabetes adults (LADA).Analyses were based data from a Swedish case-control study incident cases LADA (n=89) (n=462)...
Abstract Background Both insulin and thiazolidinediones (TZDs) are effective in the treatment of hyperglycaemia amelioration resistance type 2 diabetes but have side effects including weight gain fluid retention. The use TZDs has been further hampered by risk adverse cardiovascular events heart failure. present study evaluated effect pioglitazone or glargine on cardiac function size as well surrogate markers retention such weight, haemoglobin natriuretic peptides. Methods Thirty patients...
Abstract Aims Coffee consumption is associated with a reduced risk of Type 2 diabetes. Our aim was to investigate if coffee intake may also reduce the latent autoimmune diabetes in adults, an form features Methods We used data from population‐based case–control study incident cases adult onset (≥ 35 years) diabetes, including 245 adults (glutamic acid decarboxylase antibody positive), 759 negative), together 990 control subjects without randomly selected population. Using questionnaire...
Abstract. Objectives. To examine pioglitazone as add‐on to metformin and insulin secretagogues in patients with type 2 diabetes inadequate glycaemic control its effect on control, surrogate measures of sensitivity (adiponectin) β ‐cell function (proinsulin/insulin) fluid retention. Design setting. Prospective open‐label study 54 HbA 1c ≥6.5% admitted outpatient unit at Malmö University Hospital. The received 30–45 mg daily during 26 weeks addition their existing antidiabetic medication....
Relationship between natriuretic peptides and echocardiography parameters in patients with poorly regulated type 2 diabetes Magnus Dencker1, Martin Stagmo2, Mozhgan Dorkhan31Unit of Clinical Physiology Nuclear Medicine, Department Sciences, 2Division Cardiology, 3Division Diabetes Endocrinology, Malmö University Hospital, Malmö, SwedenAbstract: This study evaluated the relationship peptide levels a wide range population thirty-three diabetes, no known heart failure. Natriuretic brain (BNP)...
Abstract Background Diabetes is presently classified into two main forms, type 1 (T1D) and 2 diabetes (T2D), but especially T2D highly heterogeneous. A refined classification could provide a powerful tool individualize treatment regimes identify individuals with increased risk of complications already at diagnosis. Methods We applied data-driven cluster analysis (k-means hierarchical clustering) in newly diagnosed diabetic patients (N=8,980) from the Swedish ANDIS (All New Diabetics Scania)...
Sweetened beverage consumption is associated with type 2 diabetes (T2D) and LADA. We investigated to what extent this association mediated by BMI whether it modified genotypes of HLA, TCF7L2 rs7903146, or FTO rs9939609.Swedish case-control data including incident cases LADA (n = 386) T2D 1253) matched population-based controls 1545) was used. estimated adjusted ORs (95% CI) in relation sweetened intake (per daily 200 mL serving) genotypes. The impact using causal mediation methodology....
Objectives The aim of this research is to study education, income and immigration as risk factors for high hemoglobin A1c (HbA1c >70 mmol/mol (8.6%)) when diagnosed with type 2 diabetes (T2D) or latent autoimmune in the adult (LADA). Research design methods Patients were included from All New Diabetics Scania (2008-2013). Level disposable year retrieved longitudinal integrated database labour market (LISA) register compiled by Statistics Sweden. Logistic regression models used estimate...
The aim of the present study was to use real-world data from Swedish primary-care and national registries understand clinical outcomes in patients with Type 2 diabetes (T2D) treated liraglutide practice, compare those sitagliptin. This a non-interventional, retrospective conducted between February 2014 September using T2D patient centers healthcare registries. primary objective assess effectiveness control glycemia body weight practice (stage 1). secondary sitagliptin on glycemic...
To validate a test for independent assessment of insulin secretion and sensitivity during the same occasion metabolic studies in clinical practice, i.e. combined glucagon-stimulated C-peptide tolerance (GITT).We measured response to 0.5 mg intravenous glucagon followed 30 min later by administration 0.05 U kg(-1) (insulin test, ITT). Ten subjects with normal glucose participated on different days an ITT, glucagon-C-peptide ITT establish whether how tests could be combined. The was then...
Long-term insulin exposure has been implicated in breast cancer etiology, but epidemiological evidence remains inconclusive. The aims of this study were to investigate the association therapy with mammographic density (MD) as an intermediate phenotype for and assess associations long-term elevated circulating levels using a genetic score comprising 18 insulin-associated variants.We used data from KARolinska MAmmography (Karma) project, Swedish mammography screening cohort. Insulin-treated...