Felix R. Day

ORCID: 0000-0003-3789-7651
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Genetic Associations and Epidemiology
  • Birth, Development, and Health
  • Epigenetics and DNA Methylation
  • Ovarian function and disorders
  • Genetic and phenotypic traits in livestock
  • Nutrition, Genetics, and Disease
  • Growth Hormone and Insulin-like Growth Factors
  • Hypothalamic control of reproductive hormones
  • Adipose Tissue and Metabolism
  • Reproductive Biology and Fertility
  • Genetic Mapping and Diversity in Plants and Animals
  • Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
  • RNA Research and Splicing
  • Obesity, Physical Activity, Diet
  • RNA modifications and cancer
  • Genetic Syndromes and Imprinting
  • Ovarian cancer diagnosis and treatment
  • Genetics, Aging, and Longevity in Model Organisms
  • BRCA gene mutations in cancer
  • Regulation of Appetite and Obesity
  • Health, Environment, Cognitive Aging
  • Sexual Differentiation and Disorders
  • Genomics and Chromatin Dynamics
  • Lipid metabolism and disorders
  • Genetics and Physical Performance

MRC Epidemiology Unit
2016-2025

University of Cambridge
2016-2025

Wellcome/MRC Institute of Metabolic Science
2020-2025

Medical Research Council
2013-2024

Phillips Exeter Academy
2024

Engineering Service Center und Handel (Germany)
2024

Wellcome Trust
2019-2023

Cambridge School
2015-2021

National Nuclear Security Administration
2021

National Academies of Sciences, Engineering, and Medicine
2021

Sonja I. Berndt Stefan Gustafsson Reedik Mägi Andrea Ganna Eleanor Wheeler and 95 more Mary F. Feitosa Anne E. Justice Keri L. Monda Damien C. Croteau‐Chonka Felix R. Day Tõnu Esko Tove Fall Teresa Ferreira Davide Gentilini Anne Jackson Jian’an Luan Joshua C. Randall Sailaja Vedantam Cristen J. Willer Thomas W. Winkler Andrew R. Wood Tsegaselassie Workalemahu Yi‐Juan Hu Sang Lee Liming Liang Dan-Yu Lin Josine L. Min Benjamin M. Neale Guðmar Þorleifsson Jian Yang Eva Albrecht Najaf Amin Jennifer L. Bragg‐Gresham Gemma Cadby Martin den Heijer Niina Eklund Krista Fischer Anuj Goel Jouke‐Jan Hottenga Jennifer E. Huffman Ivonne Jarick Åsa Johansson Toby Johnson Stavroula Kanoni Marcus E. Kleber Inke R. König Kati Kristiansson Zoltán Kutalik Claudia Lamina Cécile Lecœur Li Guo Massimo Mangino Wendy L. McArdle Carolina Medina‐Gómez Martina Müller‐Nurasyid Julius S. Ngwa Ilja M. Nolte Lavinia Paternoster Sonali Pechlivanis Markus Perola Marjolein J. Peters Michael Preuß Lynda M. Rose Jianxin Shi Dmitry Shungin Albert V. Smith Rona J. Strawbridge Ida Surakka Alexander Teumer Mieke D. Trip Jonathan P. Tyrer Jana V. van Vliet‐Ostaptchouk Liesbeth Vandenput Lindsay L. Waite Wei Zhao Devin Absher Folkert W. Asselbergs Mustafa Atalay Antony Attwood Anthony J. Balmforth Hanneke Basart John Beilby Lori L. Bonnycastle Paolo Brambilla Marcel Bruinenberg Harry Campbell Daniel I. Chasman Peter S. Chines Francis S. Collins John Connell William Cookson Ulf dé Fairé Femmie de Vegt Mariano Dei Maria Dimitriou Sarah Edkins Karol Estrada David M. Evans Martin Farrall Maurizio Ferrario

10.1038/ng.2606 article EN Nature Genetics 2013-04-07
John R. B. Perry Felix R. Day Cathy E. Elks Patrick Sulem Deborah J. Thompson and 95 more Teresa Ferreira Chunyan He Daniel I. Chasman Tõnu Esko Guðmar Þorleifsson Eva Albrecht Wei Ang Tanguy Corre Diana L. Cousminer Bjarke Feenstra Nora Franceschini Andrea Ganna Andrew D. Johnson Sanela Kjellqvist Kathryn L. Lunetta George McMahon Ilja M. Nolte Lavinia Paternoster Eleonora Porcu Albert V. Smith Lisette Stolk Alexander Teumer Natalia Tšernikova Emmi Tikkanen Sheila Ulivi Erin K. Wagner Najaf Amin Laura J. Bierut Enda M. Byrne Jouke‐Jan Hottenga Daniel L. Koller Massimo Mangino Tune H. Pers Laura M. Yerges-Armstrong Jing Hua Zhao Irene L. Andrulis Hoda Anton‐Culver Femke Atsma Stefania Bandinelli Matthias W. Beckmann Javier Benı́tez Carl Blomqvist Stig E. Bojesen Manjeet K. Bolla Bernardo Bonanni Hiltrud Brauch Hermann Brenner Julie E. Buring Jenny Chang‐Claude Stephen J. Chanock Jinhui Chen Georgia Chenevix‐Trench J. Margriet Collée Fergus J. Couch David Couper Andrea D. Coviello Angela Cox Kamila Czene Pio D’Adamo George Davey Smith Immaculata De Vivo Ellen W. Demerath Joe Dennis Peter Devilee Aida Karina Dieffenbach Alison M. Dunning Guðný Eiríksdóttir Johan G. Eriksson Peter A. Fasching Luigi Ferrucci Dieter Flesch‐Janys Henrik Flyger Tatiana Foroud Lude Franke Melissa E. Garcia Montserrat García‐Closas Frank Geller Eco J. C. de Geus Graham G. Giles Daníel F. Guðbjartsson Vilmundur Guðnason Pascal Guénel Suiqun Guo Per Hall Ute Hamann Robin Haring Catharina A. Hartman Andrew C. Heath Albert Hofman Maartje J. Hooning John L. Hopper Frank B. Hu David J. Hunter David Karasik Douglas P. Kiel

10.1038/nature13545 article EN Nature 2014-07-23
Felix R. Day Deborah J. Thompson Hannes Helgason Daniel I. Chasman Hilary K. Finucane and 95 more Patrick Sulem Katherine S. Ruth Sean Whalen Abhishek Sarkar Eva Albrecht Elisabeth Altmaier Marzyeh Amini Caterina Barbieri Thibaud Boutin Archie Campbell Ellen W. Demerath Ayush Giri Chunyan He Jouke‐Jan Hottenga Robert Karlsson Ivana Kolčić Po−Ru Loh Kathryn L. Lunetta Massimo Mangino Marco Brumat George McMahon Sarah E. Medland Ilja M. Nolte Raymond Noordam Teresa Nutile Lavinia Paternoster Natalia Perjakova Eleonora Porcu Lynda M. Rose Katharina E. Schraut Ayellet V. Segrè Albert V. Smith Lisette Stolk Alexander Teumer Irene L. Andrulis Stefania Bandinelli Matthias W. Beckmann Javier Benı́tez Sven Bergmann Murielle Bochud Eric Boerwinkle Stig E. Bojesen Manjeet K. Bolla Judith S. Brand Hiltrud Brauch Hermann Brenner Linda Broer Thomas Brüning Julie E. Buring Harry Campbell Eulalia Catamo Stephen J. Chanock Georgia Chenevix‐Trench Tanguy Corre Fergus J. Couch Diana L. Cousminer Angela Cox Laura Crisponi Kamila Czene George Davey Smith Eco J. C. de Geus Renée de Mutsert Immaculata De Vivo Joe Dennis Peter Devilee Isabel dos‐Santos‐Silva Alison M. Dunning Johan G. Eriksson Peter A. Fasching Lindsay Fernández‐Rhodes Luigi Ferrucci Dieter Flesch‐Janys Lude Franke Marike Gabrielson Ilaria Gandin Graham G. Giles Harald Grallert Daníel F. Guðbjartsson Pascal Guénel Per Hall Emily Hallberg Ute Hamann Tamara B. Harris Catharina A. Hartman Gerardo Heiss Maartje J. Hooning John L. Hopper Frank B. Hu David J. Hunter M. Arfan Ikram Hae Kyung Im Marjo‐Riitta Järvelin Peter K. Joshi David Karasik Manolis Kellis

10.1038/ng.3841 article EN Nature Genetics 2017-04-24

Abstract Early puberty timing is associated with higher risks for type 2 diabetes (T2D) and cardiovascular disease in women therefore represents a potential target early preventive interventions. We characterised the range of diseases other adverse health outcomes or late men very large UK Biobank study. Recalled past/current were self-reported by questionnaire. limited analyses to individuals White ethnicity (250,037 women; 197,714 men) at least 500 cases (~0·2% prevalence) we applied...

10.1038/srep11208 article EN cc-by Scientific Reports 2015-06-18
Joshua C. Randall Thomas W. Winkler Zoltán Kutalik Sonja I. Berndt Anne Jackson and 95 more Keri L. Monda Tuomas O. Kilpeläinen Tõnu Esko Reedik Mägi Shengxu Li Tsegaselassie Workalemahu Mary F. Feitosa Damien C. Croteau‐Chonka Felix R. Day Tove Fall Teresa Ferreira Stefan Gustafsson Adam E. Locke Iain Mathieson André Scherag Sailaja Vedantam Andrew R. Wood Liming Liang Valgerður Steinthórsdóttir Guðmar Þorleifsson Emmanouil T. Dermitzakis Antigone S. Dimas Fredrik Karpe Josine L. Min Geoffrey C. Nicholson Deborah J. Clegg Thomas N. Person Jon P. Krohn Sabrina Bauer Christa Buechler Kristina Eisinger Amélie Bonnefond Philippe Froguel Jouke‐Jan Hottenga Inga Prokopenko Lindsay L. Waite Tamara B. Harris Albert V. Smith Alan R. Shuldiner Wendy L. McArdle Mark J. Caulfield Patricia B. Munroe Henrik Grönberg Yii-Der Ida Chen Li Guo J. Beckmann Toby Johnson Unnur Þorsteinsdóttir Maris Teder‐Laving Kay‐Tee Khaw Nicholas J. Wareham Wei Zhao Najaf Amin Ben A. Oostra Aldi T. Kraja Michael A. Province L. Adrienne Cupples Nancy L. Heard‐Costa Jaakko Kaprio Samuli Ripatti Ida Surakka Francis S. Collins Jouko Saramies Jaakko Tuomilehto Antti Jula Veikko Salomaa Jeanette Erdmann Christian Hengstenberg Christina Loley Heribert Schunkert Claudia Lamina H.-Erich Wichmann Eva Albrecht Christian Gieger Andrew A. Hicks Åsa Johansson Peter P. Pramstaller Sekar Kathiresan Elizabeth K. Speliotes Brenda W.J.H. Penninx Anna-Liisa Hartikainen Marjo‐Riitta Järvelin Ulf Gyllensten Dorret I. Boomsma Harry Campbell James F. Wilson Stephen J. Chanock Martin Farrall Anuj Goel Carolina Medina‐Gómez Fernando Rivadeneira Karol Estrada André G. Uitterlinden Albert Hofman M. Carola Zillikens

Given the anthropometric differences between men and women previous evidence of sex-difference in genetic effects, we conducted a genome-wide search for sexually dimorphic associations with height, weight, body mass index, waist circumference, hip waist-to-hip-ratio (133,723 individuals) took forward 348 SNPs into follow-up (additional 137,052 total 94 studies. Seven loci displayed significant (FDR<5%), including four previously established (near GRB14/COBLL1, LYPLAL1/SLC30A10, VEGFA,...

10.1371/journal.pgen.1003500 article EN cc-by PLoS Genetics 2013-06-06
Felix R. Day Katherine S. Ruth Deborah J. Thompson Kathryn L. Lunetta Natalia Pervjakova and 95 more Daniel I. Chasman Lisette Stolk Hilary K. Finucane Patrick Sulem Brendan Bulik‐Sullivan Tõnu Esko Andrew D. Johnson Cathy E. Elks Nora Franceschini Chunyan He Elisabeth Altmaier Jennifer A. Brody Lude Franke Jennifer E. Huffman Margaux F. Keller Patrick F. McArdle Teresa Nutile Eleonora Porcu Antonietta Robino Lynda M. Rose Ursula M. Schick Jennifer A. Smith Alexander Teumer Michela Traglia Dragana Vuckovic Jie Yao Wei Zhao Eva Albrecht Najaf Amin Tanguy Corre Jouke‐Jan Hottenga Massimo Mangino Albert V. Smith Toshiko Tanaka Gonçalo R. Abecasis Irene L. Andrulis Hoda Anton‐Culver Antonis C. Antoniou Volker Arndt Alice M. Arnold Caterina Barbieri Matthias W. Beckmann Alicia Beeghly‐Fadiel Javier Benı́tez Leslie Bernstein Suzette J. Bielinski Carl Blomqvist Eric Boerwinkle Natalia Bogdanova Stig E. Bojesen Manjeet K. Bolla Anne‐Lise Børresen‐Dale Thibaud Boutin Hiltrud Brauch Hermann Brenner Thomas Brüning Barbara Burwinkel Archie Campbell Harry Campbell Stephen J. Chanock J. Ross Chapman Yii-Der Ida Chen Georgia Chenevix‐Trench Fergus J. Couch Andrea D. Coviello Angela Cox Kamila Czene Hatef Darabi Immaculata De Vivo Ellen W. Demerath Joe Dennis Peter Devilee Thilo Dörk Isabel dos‐Santos‐Silva Alison M. Dunning John D. Eicher Peter A. Fasching Jessica D. Faul Jonine D. Figueroa Dieter Flesch‐Janys Ilaria Gandin Melissa E. Garcia Montserrat García‐Closas Graham G. Giles Giorgia Girotto Mark S. Goldberg Anna González‐Neira Mark O. Goodarzi Megan L. Grove Daníel F. Guðbjartsson Pascal Guénel Xiuqing Guo Christopher A. Haiman Per Hall Ute Hamann

10.1038/ng.3412 article EN Nature Genetics 2015-09-28

Abstract Polycystic ovary syndrome (PCOS) is the most common reproductive disorder in women, yet there little consensus regarding its aetiology. Here we perform a genome-wide association study of PCOS up to 5,184 self-reported cases White European ancestry and 82,759 controls, with follow-up further ∼2,000 clinically validated ∼100,000 controls. We identify six signals for at statistical significance ( P &lt;5 × 10 −8 ), in/near genes ERBB4/HER4 , YAP1 THADA FSHB RAD50 KRR1. Variants three...

10.1038/ncomms9464 article EN cc-by Nature Communications 2015-09-29
Josine L. Min Gibran Hemani Eilís Hannon Koen F. Dekkers Juan Castillo‐Fernandez and 95 more René Luijk Elena Carnero‐Montoro Daniel J. Lawson Kimberley Burrows Matthew Suderman Andrew D. Bretherick Tom G. Richardson Johanna Klughammer Valentina Iotchkova Gemma C. Sharp Ahmad Al Khleifat Aleksey Shatunov Alfredo Iacoangeli Wendy L. McArdle Karen Ho Ashish Kumar Cilla Söderhäll Carolina Soriano‐Tárraga Eva Giralt‐Steinhauer Nabila Kazmi Dan Mason Allan F. McRae David L. Corcoran Karen Sugden Silva Kasela Alexia Cardona Felix R. Day Giovanni Cugliari Clara Viberti Simonetta Guarrera Michael C. Lerro Richa Gupta Sailalitha Bollepalli Pooja R. Mandaviya Yanni Zeng Toni‐Kim Clarke Rosie M. Walker Vanessa Schmoll Darina Czamara Carlos Ruiz-Arenas Faisal I. Rezwan Riccardo E. Marioni Tian Lin Yvonne Awaloff Marine Germain Dylan Aïssi Ramona Zwamborn Kristel van Eijk Annelot M. Dekker Jenny van Dongen Jouke‐Jan Hottenga Gonneke Willemsen Cheng‐Jian Xu Guillermo Barturen Francesc Català‐Moll Martin Kerick Carol A. Wang Phillip E. Melton Hannah R. Elliott Jean Shin Manon Bernard İdil Yet Melissa Smart T.J. Gorrie-Stone Chris Shaw Ammar Al‐Chalabi Susan M. Ring Göran Pershagen Erik Melén Jordi Jiménez‐Conde Jaume Roquer Debbie A. Lawlor John Wright Nicholas G. Martin Grant W. Montgomery Terrie E. Moffitt Richie Poulton Tõnu Esko Lili Milani Andres Metspalu John R. B. Perry Ken K. Ong Nicholas J. Wareham Giuseppe Matullo Carlotta Sacerdote Salvatore Panico Avshalom Caspi Louise Arseneault France Gagnon Miina Ollikainen Jaakko Kaprio Janine F. Felix Fernando Rivadeneira Henning Tiemeier Marinus H. van IJzendoorn

10.1038/s41588-021-00923-x article EN Nature Genetics 2021-09-01
Matthew R. Robinson Aaron Kleinman Mariaelisa Graff Anna A. E. Vinkhuyzen David Couper and 95 more Michael B. Miller Wouter J. Peyrot Abdel Abdellaoui Brendan P. Zietsch Ilja M. Nolte Jana V. van Vliet‐Ostaptchouk Harold Snieder Behrooz Z. Alizadeh H. Marike Boezen Lude Franke Pim van der Harst Gerjan Navis Marianne G. Rots Harold Snieder Morris A. Swertz Bruce H. R. Wolffenbuttel Cisca Wijmenga Gonçalo R. Abecasis Devin Absher Helene Alavere Eva Albrecht Hana Lango Allen Peter Almgren Najaf Amin Philippe Amouyel Denise Anderson Alice M. Arnold Dominique Arveiler Thor Aspelund Folkert W. Asselbergs Themistocles L. Assimes Mustafa Atalay Antony Attwood Larry D. Atwood Stephan J. L. Bakker Beverley Balkau Anthony J. Balmforth Cristina Barlassina Inês Barroso Hanneke Basart Sabrina Bauer J. Beckmann John Beilby Amanda J. Bennett Yoav Ben‐Shlomo Richard N. Bergman Sven Bergmann Sonja I. Berndt Reiner Biffar Anna Maria Di Blasio Bernhard O. Boehm Michael Boehnke Heiner Boeing Eric Boerwinkle Jennifer L. Bolton Amélie Bonnefond Lori L. Bonnycastle Dorret I. Boomsma Ingrid B. Borecki Stefan R. Bornstein Nabila Bouatia‐Naji Gabrielle Boucher Jennifer L. Bragg‐Gresham Paolo Brambilla Marcel Bruinenberg Thomas A. Buchanan Christa Buechler Gemma Cadby Harry Campbell Mark J. Caulfield Christine Cavalcanti-Proença G Cesana Stephen J. Chanock Daniel I. Chasman Yii‐Der Ida Chen Peter S. Chines Deborah J. Clegg Lachlan Coin Francis S. Collins John Connell William Cookson Matthew N. Cooper Damien C. Croteau‐Chonka L. Adrienne Cupples Daniele Cusi Felix R. Day Ian N.M. Day George Dedoussis Mariano Dei Panos Deloukas Emmanouil T. Dermitzakis Antigone S. Dimas Maria Dimitriou Anna Dixon Marcus Dörr

10.1038/s41562-016-0016 article EN Nature Human Behaviour 2017-01-09
Katherine S. Ruth Felix R. Day Jazib Hussain Ana Martínez-Marchal Catherine Aiken and 95 more Ajuna Azad Deborah J. Thompson Lucie Knoblochová Hironori Abe Jane L. Tarry‐Adkins Javier Martín‐González Pierre Fontanillas Annique Claringbould Olivier B. Bakker Patrick Sulem Robin Walters Chikashi Terao Sandra Turon Momoko Horikoshi Kuang Lin N. Charlotte Onland‐Moret Aditya Sankar Emil Peter Thrane Hertz Pascal Timshel Vallari Shukla Rehannah Borup Kristina Wendelboe Olsen Paula Aguilera Mònica Ferrer‐Roda Yan Huang Stasa Stankovic Paul R. H. J. Timmers Thomas U. Ahearn Behrooz Z. Alizadeh Elnaz Naderi Irene L. Andrulis Alice M. Arnold Kristan J. Aronson Annelie Augustinsson Stefania Bandinelli Caterina Barbieri Robin N. Beaumont Heiko Becher Matthias W. Beckmann Stefania Benónísdóttir Sven Bergmann Murielle Bochud Eric Boerwinkle Stig E. Bojesen Manjeet K. Bolla Dorret I. Boomsma Nicholas Bowker Jennifer A. Brody Linda Broer Julie E. Buring Archie Campbell Harry Campbell Jose E. Castelao Eulalia Catamo Stephen J. Chanock Georgia Chenevix‐Trench Marina Ciullo Tanguy Corre Fergus J. Couch Angela Cox Laura Crisponi Simon S. Cross Francesco Cucca Kamila Czene George Davey Smith Eco J. C. de Geus Renée de Mutsert Immaculata De Vivo Ellen W. Demerath Joe Dennis Alison M. Dunning Miriam Dwek Mikael Eriksson Tõnu Esko Peter A. Fasching Jessica D. Faul Luigi Ferrucci Nora Franceschini Timothy M. Frayling Manuela Gago‐Dominguez Massimo Mezzavilla Montserrat García‐Closas Christian Gieger Graham G. Giles Harald Grallert Daníel F. Guðbjartsson Vilmundur Guðnason Pascal Guénel Christopher A. Haiman Niclas Håkansson Per Hall Caroline Hayward Chunyan He Wei He Gerardo Heiss

10.1038/s41586-021-03779-7 article EN Nature 2021-08-04
Coming Soon ...