Ilja M. Nolte
- Genetic Associations and Epidemiology
- Lymphoma Diagnosis and Treatment
- Genetic Mapping and Diversity in Plants and Animals
- Immune Cell Function and Interaction
- Birth, Development, and Health
- Genetic and phenotypic traits in livestock
- Nutrition, Genetics, and Disease
- Cardiac electrophysiology and arrhythmias
- Epigenetics and DNA Methylation
- Inflammatory Bowel Disease
- Viral-associated cancers and disorders
- Bioinformatics and Genomic Networks
- Child and Adolescent Psychosocial and Emotional Development
- Cognitive Abilities and Testing
- Obesity, Physical Activity, Diet
- Renal and Vascular Pathologies
- Cancer-related molecular mechanisms research
- Asthma and respiratory diseases
- Hormonal Regulation and Hypertension
- Heart Rate Variability and Autonomic Control
- Genetic Syndromes and Imprinting
- Organ Donation and Transplantation
- Liver Disease Diagnosis and Treatment
- Cardiovascular Disease and Adiposity
- Adipokines, Inflammation, and Metabolic Diseases
University Medical Center Groningen
2016-2025
University of Groningen
2016-2025
University of Bristol
2024
Bristol Regional Medical Center
2024
Massachusetts General Hospital
2024
University of Cambridge
2024
University of Tartu
2024
RELX Group (United States)
2022
Utrecht University
2021
Weatherford College
2021
A scavenger that protects the heart Coronary disease is a tale of two forms plasma cholesterol. In contrast to well-established effects “bad” cholesterol (LDL-C), role “good” (HDL-C) mysterious. Elevated HDL-C correlates with lower risk disease, yet drugs raise levels do not reduce risk. Zanoni et al. found some people exceptionally high carry rare sequence variant in gene encoding major receptor, receptor BI. This destroys receptor's ability take up HDL-C. Interestingly, this have higher...
Hypertension is a heritable and major contributor to the global burden of disease. The sum rare common genetic variants robustly identified so far explain only 1%–2% population variation in BP hypertension. This suggests existence more undiscovered variants. We conducted genome-wide association study 1,621 hypertensive cases 1,699 controls follow-up validation analyses 19,845 16,541 using an extreme case-control design. locus on chromosome 16 5′ region Uromodulin (UMOD; rs13333226, combined...