A5069150949- Nutritional Studies and Diet
- Nutrition and Health in Aging
- Blood Pressure and Hypertension Studies
- Cardiovascular Health and Disease Prevention
- Frailty in Older Adults
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Cerebrovascular and Carotid Artery Diseases
- Dementia and Cognitive Impairment Research
- Health disparities and outcomes
- Acute Ischemic Stroke Management
- Cardiovascular Health and Risk Factors
- Lipoproteins and Cardiovascular Health
- Alcohol Consumption and Health Effects
- Geriatric Care and Nursing Homes
- Adipokines, Inflammation, and Metabolic Diseases
- Heart Rate Variability and Autonomic Control
- Health Systems, Economic Evaluations, Quality of Life
- Cardiovascular Disease and Adiposity
- Diet and metabolism studies
- Obstructive Sleep Apnea Research
- Sodium Intake and Health
- Stroke Rehabilitation and Recovery
- Nutrition, Health and Food Behavior
- Neuroscience of respiration and sleep
- Obesity, Physical Activity, Diet
Osaka International Cancer Institute
2015-2024
Tokyo Metropolitan Institute of Gerontology
2016-2024
Osaka University
2012-2024
Health Center
2021-2024
University of Tsukuba
2001-2024
Ehime University
1998-2024
Weatherford College
2024
Juntendo University Hospital
2024
Shimizu (Japan)
2024
Dokkyo Medical University
2024
There is debate about the value of assessing levels C-reactive protein (CRP) and other biomarkers inflammation for prediction first cardiovascular events.We analyzed data from 52 prospective studies that included 246,669 participants without a history disease to investigate adding CRP or fibrinogen conventional risk factors risk. We calculated measures discrimination reclassification during follow-up modeled clinical implications initiation statin therapy after assessment fibrinogen.The...
Disease surveillance and population surveys of risk characteristics in a northeast rural community Japan (1965 census population, 7,030) are combined an attempt to relate morbidity factor trends for coronary heart disease stroke during the last 2 decades. Between 1964 1983, incidence (i.e., myocardial infarction, angina pectoris, sudden death) did not change significantly among men women ages 40-69, was lower than that stroke. The all declined about 60% both women, with significant decrease...
There is limited evidence on sarcopenia in Asian populations. This study aimed to clarify the prevalence, associated factors, and magnitude of association with mortality incident disability for combinations its components among Japanese community-dwelling older adults.We conducted a 5.8 year prospective 1851 residents aged 65 years or (50.5% women; mean age 72.0 ± 5.9) who participated health check-ups. Sarcopenia was defined according Working Group 2019 algorithm. Appendicular lean mass...
It is uncertain to what extent established cardiovascular risk factors are associated with venous thromboembolism (VTE).
Abstract To examine the relation of triglycerides with coronary heart disease among populations low mean total cholesterol, authors conducted a 15.5-year prospective study ending in 1997 11,068 Japanese aged 40–69 years (4,452 men and 6,616 women cholesterol = 4.73 mmol/liter 5.03 mmol/liter, respectively), initially free or stroke. There were 236 events comprising 133 myocardial infarctions, 68 angina pectoris events, 44 sudden cardiac deaths. The incidence was greater dose-response manner...
Few cohort studies have examined the association of carotid intima-media thickness (IMT) and plaque characteristics with risk stroke in apparently healthy persons. We relationship IMT surface, morphology, calcification plaques incidence among Japanese men.Carotid were evaluated bilaterally ultrasonography 1289 men aged 60 to 74 years without a previous or coronary heart disease. In this cohort, subsequent was investigated.During 4.5-year follow-up, 34 strokes occurred. The...
BACKGROUND The objective of this study was to examine the relation high-density lipoprotein cholesterol (HDL-C) coronary heart disease in Japanese men whose serum total is low by Western standards. METHODS AND RESULTS A prospective, observational based on 7.7 years follow-up for incidence and stroke conducted. subjects were 6408 middle-aged male workers aged 40 59 at baseline urban companies Osaka, Japan, mean 5.10 mmol/L. Mean HDL-C adjusted age, cholesterol, systolic blood pressure,...
Background and Purpose— Limited evidence was available on the metabolic syndrome risk of cardiovascular disease in Asia. The purpose this study is to examine association ischemic Japanese men women. Methods— We conducted an 18-year prospective 9087 people aged 40 69 years (3595 5492 women), initially free heart or stroke. During follow-up, there were 116 (74 42 women) cases 256 (144 112 strokes. Metabolic defined by modified criteria National Cholesterol Education Program Adult Treatment...
All health insurers in Japan are mandated to provide Specific Health Checkups and Guidance (SHG) focusing on metabolic syndrome (MetS) middle-aged adults, beginning 2008; intensive HG for individuals who have abdominal obesity two or more additional MetS risk factors, motivational with one factor. The aim of this study is describe medium-term changes indexes groups using the National Database.
Evidence linking the gut-brain axis to Alzheimer's disease (AD) is accumulating, but characteristics of causally important microbes are poorly understood. We perform a fecal microbiome analysis in healthy subjects and those with mild cognitive impairment (MCI) AD. find that Faecalibacterium prausnitzii (F. prausnitzii) correlates scores decreases MCI group compared group. Two isolated strains from group, live Fp360 pasteurized Fp14, improve an AD mouse model. Whole-genome comparison reveals...
Although frailty and cognitive impairment are critical risk factors for disability mortality in the general population of older inhabitants, prevalence incidence these individuals treated specialty outpatient clinics unknown. We recently established a clinic comprehensive assessments conditions such as frailty, sarcopenia, cognition, planned 3-year prospective observational study to identify progression aging-related statuses. To date, we recruited 323 patients who revealed symptoms...
Abstract Objective To clarify the rate of oral frailty and hypofunction in rural community‐dwelling older adults Japan. Background Recently, function Japanese has been evaluated multilaterally based on two concepts: hypofunction. Oral is defined as a decrease accompanied by mental physical functions. disease where comprehensively decreased. However, their rates have not yet elucidated. Materials methods were 679 from areas. investigate differences occurrence due to evaluation methods, one...
Aim This study examined the short‐term effects of participation in Kayoi‐no‐ba – community gathering places for residents to contribute care prevention with support volunteers Japan on frailty status during coronavirus disease 2019 (COVID‐19) pandemic, based a 1‐year longitudinal older adults. Methods Participants ( n = 3899) were aged ≥65 years. At baseline, they classified into four groups, their frequency before and after COVID‐19 pandemic: nonparticipation group, continued interrupted...
Understanding the effects of alcohol intake on stroke and other cardiovascular diseases is an important issue for public health.A 10.5-year prospective study relationship between disease incidence was conducted in 2890 men, aged 40 to 69 years free a history coronary heart disease, three rural communities Japan.One hundred seventy-eight strokes (40 intracerebral hemorrhages, 18 subarachnoid 104 nonhemorrhagic strokes, 16 unclassified strokes), 34 events, 19 sudden deaths occurred. Drinkers >...