A5062300791- Substance Abuse Treatment and Outcomes
- Alcohol Consumption and Health Effects
- Health disparities and outcomes
- Physical Activity and Health
- Cardiac Health and Mental Health
- Global Health Care Issues
- Cardiovascular Health and Disease Prevention
- Workplace Health and Well-being
- Blood Pressure and Hypertension Studies
- Cardiovascular and exercise physiology
- Opioid Use Disorder Treatment
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Psychosomatic Disorders and Their Treatments
- Heart Rate Variability and Autonomic Control
- Cardiovascular Health and Risk Factors
- Nutritional Studies and Diet
- Adipokines, Inflammation, and Metabolic Diseases
- Employment and Welfare Studies
- Liver Disease Diagnosis and Treatment
- Thermoregulation and physiological responses
- Cardiovascular Function and Risk Factors
- Migration, Health and Trauma
- Neurotransmitter Receptor Influence on Behavior
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Homelessness and Social Issues
University of Eastern Finland
2015-2024
Laurea University of Applied Sciences
2021
Finland University
1998-2020
University of California, Los Angeles
2014-2016
Center For Policy Research
2016
UCLA Health
2016
Center for Environmental Health
2016
Universidade Federal Fluminense
2015
Center for Research in Environmental Epidemiology
2015
Päijät-Hämeen Keskussairaala
2014
There is debate about the value of assessing levels C-reactive protein (CRP) and other biomarkers inflammation for prediction first cardiovascular events.We analyzed data from 52 prospective studies that included 246,669 participants without a history disease to investigate adding CRP or fibrinogen conventional risk factors risk. We calculated measures discrimination reclassification during follow-up modeled clinical implications initiation statin therapy after assessment fibrinogen.The...
BackgroundLow-risk limits recommended for alcohol consumption vary substantially across different national guidelines. To define thresholds associated with lowest risk all-cause mortality and cardiovascular disease, we studied individual-participant data from 599 912 current drinkers without previous disease.MethodsWe did a combined analysis of three large-scale sources in 19 high-income countries (the Emerging Risk Factors Collaboration, EPIC-CVD, the UK Biobank). We characterised...
Background Even though previous studies have suggested an association between high fish intake and reduced coronary heart disease (CHD) mortality, men in Eastern Finland, who a intake, exceptionally CHD mortality. We hypothesized that this paradox could be part explained by mercury content fish. Methods Results studied the relation of dietary mercury, as well hair urinary excretion to risk acute myocardial infarction (AMI) death from CHD, cardiovascular (CVD), any cause 1833 aged 42 60 years...
<h3>Context</h3>The value of assessing various emerging lipid-related markers for prediction first cardiovascular events is debated.<h3>Objective</h3>To determine whether adding information on apolipoprotein B and A-I, lipoprotein(a), or lipoprotein-associated phospholipase A<sub>2</sub> to total cholesterol high-density lipoprotein (HDL-C) improves disease (CVD) risk prediction.<h3>Design, Setting, Participants</h3>Individual records were available 165 544 participants without baseline CVD...
<h3>Importance</h3> It is uncertain whether depressive symptoms are independently associated with subsequent risk of cardiovascular diseases (CVDs). <h3>Objective</h3> To characterize the association between and CVD incidence across spectrum lower mood. <h3>Design, Setting, Participants</h3> A pooled analysis individual-participant data from Emerging Risk Factors Collaboration (ERFC; 162 036 participants; 21 cohorts; baseline surveys, 1960-2008; latest follow-up, March 2020) UK Biobank (401...
Cynical hostility has been associated with increased cardiovascular morbidity and mortality; yet few studies have investigated this relation in population-based samples, little is known about underlying mechanisms. This study examined the association between hostility, measured by eight-item Distrust Scale, risk for all-cause mortality incident myocardial infarction. Subjects were 2,125 men, ages 42–60 years, from Kuopio lschemic Heart Disease Risk Factor Study, a longitudinal of...
<h3>Abstract</h3> <b>Objective:</b> To examine the association between beer binging (regular sessions of heavy drinking) and mortality. <b>Design:</b> Prospective population based study with baseline assessment level alcohol intake (dose), by type drink drinking pattern, previous existing diseases, socioeconomic background, occupational status, involvement in organisations during leisure time, physical activity body mass index, blood pressure, serum lipids plasma fibrinogen concentration, an...
Objectives: To examine the influence of childhood and adult socioeconomic position, mobility, cumulative disadvantage across lifecourse on cognitive function in late middle age.
ABSTRACT Background Only few prospective population studies have been able so far to investigate depression and drinking patterns in detail. Therefore, little is known about what aspect of alcohol consumption best predicts symptoms the general population. Participants design In this population‐based two‐wave cohort study, a alcohol‐drinking men women ( n = 15 926) were followed‐up after 5 years. A postal questionnaire was sent 1998 (response proportion 40%) again 2003 80% baseline...
Abstract Background there are no previous studies linking repeated heat exposure of sauna and the risk memory diseases. We aimed to investigate whether frequency bathing is associated with dementia Alzheimer's disease. Setting prospective population-based study. Methods was assessed at baseline in Kuopio Ischaemic Heart Disease cohort study 2,315 apparently healthy men aged 42–60 years baseline, examinations conducted between 1984 1989. Hazard ratios (HRs) 95% confidence intervals (CIs) for...
The social health insurance coverage is relatively high in Mongolia; however, escalation of out-of-pocket payments for care, which reached 41 % the total expenditure 2011, a policy concern. aim this study to analyse incidence catastrophic expenditures and measure rate impoverishment from care under scheme Mongolia. We used data Household Socio-Economic Survey 2012, conducted by National Statistical Office Catastrophic are defined an excess at various thresholds household (capacity pay). For...
Early recognition of and intervention in risky alcohol consumption has been shown to be an effective way reduce the harm. However, primary care physicians are still not screening for intervening sufficiently their patients' misuse.The purpose this study was explore factors having effect on health inquiring about consumption.A qualitative physicians' experiences views based tape recorded semi-structured interviews carried out all (n = 35) working at four centres Eastern Finland.Seven main...
Objectives This study examined the association between perceived health and early retirement. Methods A cohort of 1748 men aged 42 to 60 years from eastern Finland was followed 1984 2000. At baseline, participants had answered a questionnaire regarding their general (as measured by physician diagnoses) status. Comprehensive pension records were obtained Social Insurance Institution Central Pension Security Institute. The risk disability pensioning in various disease categories...
Objective: To explore the associations between alexithymia and increased somatic morbidity. The mechanisms underlying these associations, however, are still unclear. Furthermore, data on association mortality scarce. Methods: A total of 2321 Finnish men, aged 46 to 61 years, were followed up for an average 20 years. Mortality rates obtained from national register. baseline cardiovascular disease (CVD), all-cause, injury, cancer deaths examined with adjustments age several behavioral...
Background Plasma adiponectin levels have previously been inversely associated with carotid intima‐media thickness ( IMT ), a marker of subclinical atherosclerosis. In this study, we used sex‐stratified Mendelian randomization approach to investigate whether has causal protective influence on . Methods and Results Baseline plasma concentration was tested for association baseline , progression over 30 months, occurrence cardiovascular events within 3 years in 3430 participants (women, n=1777;...
Objectives This study aimed to assess the effects of physically demanding work – measured as energy expenditure (EE) during occupational physical activities (OPA) on risk acute myocardial infarction (AMI) among men with and without preexisting ischemic heart disease (IHD). Methods The 20-year prospective examined 1891 middle-aged working using absolute (kcal/day) relative (relative aerobic strain percent oxygen uptake reserve) measures EE. Linear quadratic hazard models were explored in Cox...
There remains a dearth of life-course studies analyzing childhood environment and late-life chronic illness. In particular, few have addressed possible early-life predictors dementia. This study examines relationships between stress later-age dementia, specifically Alzheimer's disease (AD).We used data from 2682 men in the population-based Kuopio Ischemic Heart Disease Risk Factor Study who participated extensive baseline health examinations interviews 1984 1989, when they were 42 61 years...
BACKGROUNDSauna bathing is associated with reduced cardiovascular risk, but the mechanisms underlying this beneficial effect are not entirely understood. We aimed to assess relationship between sauna and risk of incident hypertension.