Valeria Pala
A5002407950- Nutritional Studies and Diet
- Obesity, Physical Activity, Diet
- Cancer Risks and Factors
- Consumer Attitudes and Food Labeling
- Nutrition, Genetics, and Disease
- Diet and metabolism studies
- Cancer, Lipids, and Metabolism
- Fatty Acid Research and Health
- Metabolomics and Mass Spectrometry Studies
- Liver Disease Diagnosis and Treatment
- Estrogen and related hormone effects
- Metabolism, Diabetes, and Cancer
- Nutrition and Health in Aging
- Diet, Metabolism, and Disease
- Colorectal Cancer Screening and Detection
- Regulation of Appetite and Obesity
- Bone and Dental Protein Studies
- Endometrial and Cervical Cancer Treatments
- Physical Activity and Health
- Alcohol Consumption and Health Effects
- Folate and B Vitamins Research
- Pancreatic and Hepatic Oncology Research
- Eating Disorders and Behaviors
- Growth Hormone and Insulin-like Growth Factors
- Health disparities and outcomes
Fondazione IRCCS Istituto Nazionale dei Tumori
2016-2025
Fairmont Senior High School
2025
Utrecht University
2024
Regional Health
2012-2024
Institut Gustave Roussy
2008-2020
Imperial College London
2020
University of Southern California
2012-2018
Cancer Registry of Norway
2018
University of Oslo
2018
Istituti di Ricovero e Cura a Carattere Scientifico
2012-2016
BACKGROUND Physical activity (PA) is considered a cornerstone of diabetes mellitus management to prevent complications, but conclusive evidence lacking. METHODS This prospective cohort study and meta-analysis existing studies investigated the association between PA mortality in individuals with diabetes. In EPIC (European Prospective Investigation Into Cancer Nutrition), was defined 5859 at baseline. Associations leisure-time total walking cardiovascular disease (CVD) were studied using...
Although several studies have investigated the association of Mediterranean diet with overall mortality or risk specific cancers, data on cancer are sparse. We examined between adherence to dietary pattern and using from European Prospective Investigation Into Cancer nutrition, a multi-centre prospective cohort study including 142 605 men 335 873. Adherence was score (range: 0–9) considering combined intake fruits nuts, vegetables, legumes, cereals, lipids, fish, dairy products, meat...
A higher intake of fruits and vegetables has been associated with a lower risk ischaemic heart disease (IHD), but there is some uncertainty about the interpretation this association. The objective was to assess relation between fruit vegetable mortality from IHD in European Prospective Investigation into Cancer Nutrition (EPIC)-Heart study. After an average 8.4 years follow-up, were 1636 deaths among 313 074 men women without previous myocardial infarction or stroke eight countries....
Earlier analyses within the EPIC study showed that dietary fibre intake was inversely associated with colorectal cancer risk, but results from some large cohort studies do not support this finding. We explored whether association remained after longer follow-up a near threefold increase in cases, and if varied by gender tumour location.After mean of 11.0 years, 4,517 incident cases were documented. Total, cereal, fruit, vegetable intakes estimated questionnaires at baseline. Hazard ratios...
A total of 308,036 women were selected from the European Prospective Investigation into Cancer and Nutrition (EPIC) study to evaluate association between tobacco smoking risk cervical intraepithelial neoplasia grade 3 (CIN3)/carcinoma in situ (CIS) invasive cancer (ICC). At baseline, participants completed a questionnaire provided blood samples. During mean follow-up time 9 years, 261 ICC cases 804 CIN3/CIS reported. In nested case-control study, baseline sera 609 1,218 matched controls...
Background In addition to HPV, high parity and hormonal contraceptives have been associated with cervical cancer (CC). However, most of the evidence comes from retrospective case-control studies. The aim this study is prospectively evaluate associations between factors risk developing intraepithelial neoplasia grade 3 (CIN3)/carcinoma in situ (CIS) invasive (ICC). Methods Findings We followed a cohort 308,036 women recruited European Prospective Investigation into Cancer Nutrition (EPIC)...
Background Whether and how n-3 n-6 polyunsaturated fatty acids (PUFAs) are related to type 2 diabetes (T2D) is debated. Objectively measured plasma PUFAs can help clarify these associations. Methods Findings Plasma phospholipid were by gas chromatography among 12,132 incident T2D cases 15,919 subcohort participants in the European Prospective Investigation into Cancer Nutrition (EPIC)-InterAct study across eight countries. Country-specific hazard ratios (HRs) estimated using...
The relationship between erythrocyte membrane fatty acids and postmenopausal breast cancer risk was analyzed previously only by retrospective studies, which suggested a protective effect of increased saturation index (SI), i.e., the ratio stearic to oleic acid. We investigated relationships in prospective study hormones, diet, prediagnostic (the ORDET study) conducted northern Italy.A total 4052 women were followed for an average 5.5 years; 71 cases invasive identified. For each case...
To date, no attempt has been made to systematically determine the apportionment of hepatocellular carcinoma burden in Europe or North America among established risk factors.Using data collected from 1992 2006, which included 4,409,809 person-years European Prospective Investigation into Cancer and nutrition (EPIC), we identified 125 case patients with carcinoma, whom 115 were matched 229 control subjects. We calculated odds ratios (ORs) for association documented factors incidence this...
One of the aims EPIC study is to produce accurate descriptions dietary habits participants recruited in 27 centers 10 European countries. To do this, different assessment instruments were developed and applied capture wide range diets characterizing populations. Three food frequency questionnaires for Italy: one Varese, Turin Florence, Ragusa Naples. These inquired about eating over previous year completed by 46,839 Italian participants. Specially software analyzed responses linked them...
It is well established that parity and use of oral contraceptives reduce the risk ovarian cancer, but associations with other reproductive variables are less clear. We examined contraceptive factors cancer in European Prospective Investigation into Cancer Nutrition. Among 327 396 eligible women, 878 developed over an average 9 years. Hazard ratios (HRs) 95% confidence intervals (CIs) were estimated using Cox proportional hazard models stratified by centre age, adjusted for smoking status,...
To compare the average out-of-home (OH) consumption of foods and beverages, as well energy intake, among populations from 10 European countries to describe characteristics substantial OH eaters, defined for purpose present study, in comparison other individuals.Cross-sectional study. Dietary data were collected through single 24-hour dietary recalls, which place was recorded. For eaters those who consumed more than 25% total daily intake at locations household premises. Mean intakes...
Type 2 diabetes mellitus (T2DM) is one of the most common chronic diseases worldwide. In high-income countries, low socioeconomic status seems to be related a high incidence T2DM, but very little known about intermediate factors this relationship. Method We performed case-cohort study in eight Western European countries nested EPIC (n = 340, 234, 3.99 million person-years follow-up). A random sub-cohort 16,835 individuals and total 12,403 incident cases T2DM were identified. Crude...
Abstract Fermented dairy products like yogurt have been suggested to protect against colorectal cancer (CRC). We conducted a prospective study on 45,241 (14,178 men; 31,063 women) volunteers of the EPIC‐Italy cohort who completed dietary questionnaire including specific questions intake. During 12 years follow‐up, 289 were diagnosed with CRC. Hazard ratios (HRs) for disease and 95% confidence intervals (CIs) estimated by Cox proportional hazard models, stratified adjusted energy intake other...