Anne M. May
- Cancer survivorship and care
- Nutritional Studies and Diet
- Nutrition and Health in Aging
- Obesity, Physical Activity, Diet
- Cancer Risks and Factors
- Childhood Cancer Survivors' Quality of Life
- Colorectal Cancer Treatments and Studies
- Physical Activity and Health
- Lymphatic System and Diseases
- Cancer-related cognitive impairment studies
- Health Systems, Economic Evaluations, Quality of Life
- Diet and metabolism studies
- Cancer Immunotherapy and Biomarkers
- Cancer, Lipids, and Metabolism
- Frailty in Older Adults
- Cancer Treatment and Pharmacology
- Esophageal Cancer Research and Treatment
- Gastric Cancer Management and Outcomes
- Colorectal Cancer Screening and Detection
- CAR-T cell therapy research
- Colorectal Cancer Surgical Treatments
- Glioma Diagnosis and Treatment
- Consumer Attitudes and Food Labeling
- Economic and Financial Impacts of Cancer
- Genetic factors in colorectal cancer
University Medical Center Utrecht
2016-2025
Utrecht University
2014-2025
Instituto Nacional de Cardiología
2025
Netherlands Comprehensive Cancer Organisation
2025
Medicines Evaluation Board
2024
German Oceanographic Museum
2022-2024
Nationwide Children's Hospital
2024
Heidelberg University
2010-2023
University Hospital Heidelberg
2011-2023
The Netherlands Cancer Institute
2023
The number of cancer survivors worldwide is growing, with over 15.5 million in the United States alone-a figure expected to double coming decades. Cancer face unique health challenges as a result their diagnosis and impact treatments on physical mental well-being. For example, often experience declines functioning quality life while facing an increased risk recurrence all-cause mortality compared persons without cancer. 2010 American College Sports Medicine Roundtable was among first reports...
Previous studies have relied predominantly on the body-mass index (BMI, weight in kilograms divided by square of height meters) to assess association adiposity with risk death, but few examined whether distribution body fat contributes prediction death.We BMI, waist circumference, and waist-to-hip ratio death among 359,387 participants from nine countries European Prospective Investigation into Cancer Nutrition (EPIC). We used a Cox regression analysis, age as time variable, stratified...
Abstract Physical activity has been associated with lower risks of breast and colorectal cancer in epidemiological studies; however, it is unknown if these associations are causal or confounded. In two-sample Mendelian randomisation analyses, using summary genetic data from the UK Biobank GWA consortia, we found that a one standard deviation increment average acceleration was (odds ratio [OR]: 0.51, 95% confidence interval [CI]: 0.27 to 0.98, P-value = 0.04) (OR: 0.66, CI: 0.48 0.90, 0.01)....
Background: The higher risk of death resulting from excess adiposity may be attenuated by physical activity (PA). However, the theoretical number deaths reduced eliminating inactivity compared with overall and abdominal obesity remains unclear. Objective: We examined whether modified association between PA all-cause mortality estimated population attributable fraction (PAF) years life gained for these exposures. Design: This was a cohort study in 334,161 European men women. mean follow-up...
BACKGROUND Physical activity (PA) is considered a cornerstone of diabetes mellitus management to prevent complications, but conclusive evidence lacking. METHODS This prospective cohort study and meta-analysis existing studies investigated the association between PA mortality in individuals with diabetes. In EPIC (European Prospective Investigation Into Cancer Nutrition), was defined 5859 at baseline. Associations leisure-time total walking cardiovascular disease (CVD) were studied using...
Although several studies have investigated the association of Mediterranean diet with overall mortality or risk specific cancers, data on cancer are sparse. We examined between adherence to dietary pattern and using from European Prospective Investigation Into Cancer nutrition, a multi-centre prospective cohort study including 142 605 men 335 873. Adherence was score (range: 0–9) considering combined intake fruits nuts, vegetables, legumes, cereals, lipids, fish, dairy products, meat...
Epidemiological evidence suggests that the Mediterranean diet (MD) could reduce risk of breast cancer (BC). As from prospective studies remains scarce and conflicting, we investigated association between adherence to MD BC among 335,062 women recruited 1992 2000, in ten European countries, followed for 11 years on average. Adherence was estimated through an adapted relative (arMED) score excluding alcohol. Cox proportional hazards regression models were used while adjusting factors. A total...
Exercise started shortly after breast cancer diagnosis might prevent or diminish fatigue complaints. The Physical Activity during Cancer Treatment (PACT) study was designed to primarily examine the effects of an 18-week exercise intervention, offered in daily clinical practice setting and starting within 6 weeks diagnosis, on preventing increase fatigue.This multi-centre controlled trial randomly assigned 204 patients usual care (n = 102) supervised aerobic resistance 102). By design, all...
The oncological efficacy and safety of laparoscopic gastrectomy are under debate for the Western population with predominantly advanced gastric cancer undergoing multimodality treatment.In 10 experienced upper GI centers in Netherlands, patients resectable (cT1-4aN0-3bM0) adenocarcinoma were randomly assigned to either or open gastrectomy. No masking was performed. primary outcome hospital stay. Analyses performed by intention treat. It hypothesized that leads shorter stay, less...
To accurately examine associations of physical activity (PA) with disease outcomes, a valid method assessing free-living is required. We examined the validity brief PA questionnaire (PAQ) used in European Prospective Investigation into Cancer and Nutrition (EPIC). energy expenditure (PAEE) time spent moderate vigorous (MVPA) was measured 1,941 healthy individuals from 10 countries using individually-calibrated combined heart-rate movement sensing. Participants also completed short EPIC-PAQ,...
Transepithelial Na+ reabsorption across tight epithelia is regulated by aldosterone. The amiloride-sensitive epithelial sodium channel (ENaC) a major target for the natriferic action of In this study, effect aldosterone on ENaC mRNA abundance and rate protein synthesis each three subunits (alpha, beta gamma) in A6 kidney cell line were examined. cells grown plastic, induced large rapid increase gamma subunit abundance, but not translated into corresponding proteins. porous substrate,...
There is convincing evidence for a decreased risk of breast cancer with increased physical activity. Uncertainties remain, however, about the role different types activity on and potential effect modification these associations. We used data from 218,169 premenopausal postmenopausal women nine European countries, ages 20 to 80 years at study entry into Prospective Investigation Cancer Nutrition. Hazard ratios (HR) multivariate Cox regression models were calculated using metabolic equivalent...