A5023076001- Acute Myocardial Infarction Research
- Cardiac Imaging and Diagnostics
- Coronary Interventions and Diagnostics
- Antiplatelet Therapy and Cardiovascular Diseases
- Heart Failure Treatment and Management
- Cardiac Health and Mental Health
- Cardiovascular Function and Risk Factors
- Health Systems, Economic Evaluations, Quality of Life
- Venous Thromboembolism Diagnosis and Management
- Sex and Gender in Healthcare
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Structural Anomalies and Repair
- Congenital Heart Disease Studies
- Cardiac Valve Diseases and Treatments
- Cardiovascular Disease and Adiposity
- Cardiovascular Issues in Pregnancy
- Atrial Fibrillation Management and Outcomes
- Cardiac pacing and defibrillation studies
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Cardiovascular Effects of Exercise
- Cardiac Arrest and Resuscitation
- Cardiac electrophysiology and arrhythmias
- Heparin-Induced Thrombocytopenia and Thrombosis
- Sleep and related disorders
- Pulmonary Hypertension Research and Treatments
Linköping University
2016-2025
Region Jönköpings län
2024
Karolinska Institutet
2024
Linköping University Hospital
2009-2023
Skåne University Hospital
2023
Lund University
2023
University of Gothenburg
2019
Jönköping University
2013
University of Amsterdam
2012
Amsterdam UMC Location University of Amsterdam
2012
The direct-acting platelet P2Y12 receptor antagonist ticagrelor can reduce the incidence of major adverse cardiovascular events when administered at hospital admission to patients with ST-segment elevation myocardial infarction (STEMI). Whether prehospital administration improve coronary reperfusion and clinical outcome is unknown.
Spontaneous coronary artery dissection (SCAD) has long been recognized as a cause of acute syndromes (ACS). Initially considered very rare and associated primarily with pregnancy the peripartum period, use higher sensitivity Troponin assays early angiography in ACS, coupled greater awareness condition, led to increased diagnosis, it is now understood that SCAD represents significant ACS predominantly young middle-aged women, most cases occurring outside context recent pregnancy.1,2 Although...
Background— For the large and growing population of elderly patients with cardiovascular disease, it is important to identify clinically relevant measures biological age their contribution risk. Frailty an emerging concept in medicine denoting increased vulnerability decreased physiological reserves. We analyzed manner which variable frailty predicts short-term outcomes for non–ST-segment elevation myocardial infarction patients. Methods Results— Patients aged ≥75 years, diagnosed were...
Early detection of coronary atherosclerosis using computed tomography angiography (CCTA), in addition to artery calcification (CAC) scoring, may help inform prevention strategies. We used CCTA determine the prevalence, severity, and characteristics its association with CAC scores a general population. recruited 30 154 randomly invited individuals age 50 64 years SCAPIS (the Swedish Cardiopulmonary Bioimage Study). The study includes without known heart disease (ie, no previous myocardial...
The comparative efficacy of various anticoagulation strategies has not been clearly established in patients with acute myocardial infarction who are undergoing percutaneous coronary intervention (PCI) according to current practice, which includes the use radial-artery access for PCI and administration potent P2Y12 inhibitors without planned glycoprotein IIb/IIIa inhibitors.In this multicenter, randomized, registry-based, open-label clinical trial, we enrolled either ST-segment elevation...
Evaluation of quality care is an integral part modern healthcare, and has become indispensable tool for health authorities, the public, press patients. However, measuring difficult, because it a multifactorial multidimensional concept that cannot be estimated solely on basis patients’ clinical outcomes. Thus, process through indicators (QIs) widely used practice in this context. Other professional societies have published QIs evaluation context acute myocardial infarction (AMI), but no such...
Abstract Aims Quality indicators (QIs) are tools to improve the delivery of evidence-base medicine. In 2017, European Society Cardiology (ESC) Association for Acute Cardiovascular Care (ACVC) developed a set QIs acute myocardial infarction (AMI), which have been evaluated at national and international levels across different populations. However, an update these is needed in light accumulated experience changes supporting evidence. Methods results The ESC methodology QI development was used...
The present study aims to describe accelerometer-assessed physical activity (PA) patterns and fulfillment of PA recommendations in a large sample middle-aged men women, differences between subgroups socio-demographic, socio-economic, lifestyle-related variables. A total 27 890 (92.5% participants, 52% aged 50-64 years) women with at least four days valid hip-worn accelerometer data (Actigraph GT3X+, wGT3X+ wGT3X-BT) from the Swedish CArdioPulmonary bioImage Study, SCAPIS, were included. In...
Importance Adverse pregnancy outcomes are recognized risk enhancers for cardiovascular disease, but the prevalence of subclinical coronary atherosclerosis after these conditions is unknown. Objective To assess associations between history adverse and artery disease assessed by computed tomography angiography screening. Design, Setting, Participants Cross-sectional study a population-based cohort women in Sweden (n = 10 528) with 1 or more deliveries 1973 later, ascertained via Swedish...
Abstract. Objectives . To determine the possibility of very early prognostic stratification based on electrocardiograms (ECGs) at rest and/or cardiac enzyme levels after an episode suspected unstable coronary heart disease. Design and setting Men with angina or non‐Q‐wave myocardial infarction were studied in care units eight hospitals. The ECGs creatinine kinase followed. Subjects In total 911 men followed for 12 months. Of 8136 consecutively admitted, 3365 fulfilled inclusion criteria....
To study gender differences in management and outcome patients with non-ST-elevation acute coronary syndrome.Cohort of 53 781 consecutive (37% women) from the Register Information Knowledge about Swedish Heart Intensive care Admissions (RIKS-HIA), a diagnosis either unstable angina pectoris or myocardial infarction. All were admitted to intensive units Sweden, between 1998 2002, followed for 1 year.Treatment intensity in-hospital, 30-day 1-year mortality.Women older (73 vs 69 years, p<0.001)...
The aim of the study was to perform a feature tracking analysis on cine magnetic resonance (MR) images elucidate if functional measurements motion left ventricular wall may detect scar defined with gadolinium enhanced MR. Myocardial contraction can be measured in terms velocity, displacement and local deformation (strain) particular myocardial segment. Contraction will reduced presence as consequence blood flow. Thirty patients (3 women 27 men) were selected based or absence extensive...
In ST elevation myocardial infarction women received less evidence-based medicine and had worse outcome during the fibrinolytic era. With shift to primary percutaneous coronary intervention (pPCI) as preferred reperfusion strategy, authors aimed investigate whether these gender differences has diminished.Cohort study including consecutive patients registered 1998-2000 (n=15 697) 2004-2006 (n=14 380) in Register of Information Knowledge about Swedish Heart Intensive care Admissions.1. Use...
For the large population of elderly patients with cardiovascular disease, it is crucial to identify clinically relevant measures biological age and their contribution risk. Frailty denoting decreased physiological reserves increased vulnerability. We analysed manner in which variable frailty associated 1-year outcomes for non-ST-segment elevation myocardial infarction (NSTEMI) patients. Patients aged 75 years or older, diagnosed NSTEMI were included at three centres, clinical data including...