A5032322516- Cardiac pacing and defibrillation studies
- Cardiac Arrhythmias and Treatments
- Cardiac electrophysiology and arrhythmias
- Heart Failure Treatment and Management
- Acute Myocardial Infarction Research
- Atrial Fibrillation Management and Outcomes
- Diabetes Treatment and Management
- Cardiovascular Function and Risk Factors
- Coronary Interventions and Diagnostics
- Pleural and Pulmonary Diseases
- Systemic Sclerosis and Related Diseases
- Obesity and Health Practices
- Chronic Disease Management Strategies
- Neurological disorders and treatments
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Apelin-related biomedical research
- Cardiovascular and exercise physiology
- Cardiac Imaging and Diagnostics
- Diabetes Management and Research
- Nutrition and Health in Aging
- Air Quality and Health Impacts
- Urticaria and Related Conditions
- Climate Change and Health Impacts
- Potassium and Related Disorders
- Pericarditis and Cardiac Tamponade
Karolinska Institutet
2020-2024
Glanrhyd Hospital
2024
Karolinska University Hospital
2020-2022
Lund University
2014-2021
Danderyds sjukhus
2021
Skåne University Hospital
2015-2020
The present study aims to describe accelerometer-assessed physical activity (PA) patterns and fulfillment of PA recommendations in a large sample middle-aged men women, differences between subgroups socio-demographic, socio-economic, lifestyle-related variables. A total 27 890 (92.5% participants, 52% aged 50-64 years) women with at least four days valid hip-worn accelerometer data (Actigraph GT3X+, wGT3X+ wGT3X-BT) from the Swedish CArdioPulmonary bioImage Study, SCAPIS, were included. In...
Abstract Aims The aim was to describe the prevalence, characteristics, and outcome of patients with acute myocardial infarction (MI) developing left ventricular (LV) systolic dysfunction or pulmonary congestion by applying different criteria define population. Methods results In MI included in Swedish web‐system for enhancement development evidence‐based care heart disease (SWEDEHEART) registry, four sets were applied, creating not mutually exclusive subsets patients: ejection fraction (EF)...
BACKGROUND: The effect of myocardial infarction (MI) on life expectancy is difficult to study because the prevalence MI hinders direct comparison with general population. We sought assess this in relation age, sex, and left ventricular ejection fraction (LVEF) by comparing individuals matched comparators without previous MI. METHODS: included patients a first between 1991 2022 from nationwide SWEDEHEART registry (Swedish Web-System for Enhancement Development Evidence-Based Care Heart...
The very long-term outcome of patients who survive the first few years after receiving cardiac resynchronization therapy (CRT) has not been well described thus far. We aimed to provide outcomes, especially with regard occurrence sudden death (SCD), in CRT without (CRT-P) and defibrillator (CRT-D).A total 1775 patients, ischaemic or non-ischaemic dilated cardiomyopathy, were alive 5 implantation, enrolled this multicentre European observational cohort study. Overall mortality rates specific...
<h3>Objective</h3> Among primary prevention patients with heart failure receiving cardiac resynchronisation therapy (CRT), the impact of additional implantable cardioverter defibrillator (ICD) treatment on outcomes and its interaction sex remains uncertain. We aim to assess whether addition ICD functionality CRT devices offers a more pronounced survival benefit in men compared women, as previous research has suggested. <h3>Methods</h3> Observational multicentre cohort study 5307 consecutive...
Background Cardiac resynchronization therapy (CRT) with or without a defibrillator has positive effect on mortality and morbidity for patients heart failure. However, comparisons between CRT‐defibrillators (CRT‐D) CRT‐pacemakers (CRT‐P) are relatively scarce outside the clinical trial setting. This study aimed to assess baseline characteristics in relation long‐term prognosis treated CRT, investigate potential benefit of CRT‐D versus CRT‐P. Methods Data were retrospectively collected from...
Cardiac resynchronization therapy (CRT) is an established for appropriately selected patients with heart failure. Response to CRT has been heterogeneously defined using both clinical and echocardiographic measures, poor correlation between the two. The study cohort was comprised of 202 CRT-treated response at 6 months post-implant. Echocardiographic (E+) as a reduction in LVESV ≥ 15%, improvement 1 NYHA class (C+), biomarker 25% NT-proBNP(B+). association measures (E+, B+, C+; score range...
AimsCardiac resynchronization therapy (CRT) has a well-documented positive effect on mortality and heart failure morbidity. The aim of this study was to assess the long-term survival predictive value self-assessed functional status prognosis patients treated with CRT-pacemaker (CRT-P).
<b><i>Background:</i></b> Interatrial block (IAB) and abnormal P-wave terminal force in lead V<sub>1</sub> (PTFV<sub>1</sub>) are electrocardiographic (ECG) abnormalities that have been shown to be associated with new-onset atrial fibrillation (AF) death. However, their prognostic importance has not proven cardiac resynchronization therapy (CRT) recipients. <b><i>Objective:</i></b> To assess if IAB...
In patients with cardiac resynchronization therapy (CRT), atrial fibrillation (AF) is associated an unfavorable outcome and may cause loss of biventricular pacing (BivP). An effective delivery BivP more than 98% all ventricular beats has been shown to be a major determinant CRT-success.At Swedish tertiary referral center, data was retrospectively obtained from patient registers, medical records preoperative electrocardiograms. Data regarding AF during the first year follow-up assessed...
Objectives. Up to 50% of patients qualified for cardiac resynchronization therapy (CRT) have documented atrial fibrillation (AF) prior CRT-implantation. This finding is associated with worse prognosis but few studies evaluated the importance post-implant device-detected AF. study aimed assess prognostic impact high-rate episodes (AHRE), as a surrogate Design. Data were retrospectively obtained from consecutive receiving CRT. Baseline clinical data and CRT device-interrogations, performed at...
Objective. Evaluate if the use of active clearance chest tubes after aortic valve surgery influenced bleeding and reduced postoperative residual pericardial effusion. Design. Prospective randomised trial comparing PleuraFlow® 32 F tube with FlowGlide™ to a standard Argyle® in 100 patients undergoing surgery. Chest outputs effusion measurements assessed by two-dimensional transthoracic echocardiography were recorded before hospital discharge. Results. Postoperative per hour did not differ...
Objectives. Cardiac Resynchronization Therapy (CRT) for heart-failure patients has a well-documented positive effect, but the overall mortality in this group remains high. This study aimed to explore whether additional information from device post-implant (occurrence of ventricular high-rate episodes), could add prognostic value on CRT-pacemaker (CRT-P) treatment. Design. Clinical data and device-interrogation were retrospectively gathered medical records 220 treated with CRT-P. Ventricular...
Abstract Background Primary percutaneous coronary intervention (PCI) is the recommended reperfusion strategy in ST-elevation myocardial infarction (STEMI) patients provided time to ≤120 minutes. In presenting early with an estimated &gt;120 minutes, thrombolytic therapy should be considered according European Society of Cardiology guidelines. However, there a lack contemporary data on treated thrombolysis. Aims Our aim was determine how often thrombolysis administered STEMI having...
Abstract Background Cardiovascular disease, including acute myocardial infarction (AMI) is the leading cause of death globally.(1) While risk AMI higher with increasing age, consequences can be more severe in younger individuals, causing larger loss-of-life-expectancy and imposing burdens for society terms healthcare costs premature retirements. Description young cohort greatest interest to identify modifiable factors and/or other predisposing that may optimized. Aims To describe prevalence...
Abstract Background Cardiovascular disease is the primary cause of mortality in patients with type 2 diabetes mellitus (T2DM). Randomized controlled trials (RCT) have shown that Glucagon-like peptide-1 receptor agonists (GLP-1RA) improve cardiovascular outcomes T2DM patients, greater therapeutic benefits observed established atherosclerotic disease. However, effect GLP1-RA therapy on has been inconsistent and RCT not sufficiently powered to examine or their different subgroups patients....
Objective To assess the risk of future death and cardiac events following percutaneous coronary intervention (PCI) in patients using smokeless tobacco, snus, compared with not snus at admission for a first PCI. Methods The Swedish Coronary Angiography Angioplasty Registry is prospective registry on diagnostic procedures interventions. A total 74 958 admitted PCI were enrolled between 2009 2018, 6790 users 68 168 snus. We used Cox proportional hazards regression statistical modelling imputed...
Abstract Background LV dysfunction and symptomatic heart failure are common complications after myocardial infarction the mortality morbidity burden remain high in this population. Published data becoming dated, mainly focus on hospitalization burden. There is a lack of contemporary describing patients with post-MI terms symptom secondary prevention measures. Purpose The purpose study was to describe different degree MI, their burden, quality life adherence recommended measures nationwide...
Abstract Background Both sodium–glucose cotransporter 2 inhibitors (SGLT2i) and glucagon-like peptide-1 receptor agonists (GLP1-RA) have been shown to reduce the risk of adverse cardiovascular outcomes in type diabetes mellitus (T2DM) patients with established atherosclerotic disease. Purpose The aim this study was assess comparative effectiveness SGLT2i GLP1-RA myocardial infarction (MI) T2DM. Methods This observational cohort included MI T2DM who were treated or within 180 days hospital...
Abstract Background Advanced Inter Atrial Block (aIAB) reflects a disruption of the electrical signal between atria and develops gradually. It has been predictive atrial fibrillation death in patients with Cardiac Resynchronization Therapy (CRT). A higher number inferior ECG leads demonstrating biphasic P waves was proposed as measure aIAB severity, however its prognostic importance not proven. Purpose To assess if is associated poor prognosis CRT recipients to see there dose-response...