A5041040472- Acute Myocardial Infarction Research
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac Imaging and Diagnostics
- Coronary Interventions and Diagnostics
- Heart Failure Treatment and Management
- Atrial Fibrillation Management and Outcomes
- Health Systems, Economic Evaluations, Quality of Life
- Cardiac Health and Mental Health
- Venous Thromboembolism Diagnosis and Management
- Frailty in Older Adults
- Cardiovascular Function and Risk Factors
- Cardiac, Anesthesia and Surgical Outcomes
- Sex and Gender in Healthcare
- Cardiac Arrest and Resuscitation
- Cardiac and Coronary Surgery Techniques
- Takotsubo Cardiomyopathy and Associated Phenomena
- Medication Adherence and Compliance
- Mechanical Circulatory Support Devices
- Nutrition and Health in Aging
- Healthcare cost, quality, practices
- Cardiac Ischemia and Reperfusion
- Diabetes Treatment and Management
- Workplace Health and Well-being
- Cardiovascular Issues in Pregnancy
- Lipoproteins and Cardiovascular Health
Linköping University
2016-2025
Linköping University Hospital
2012-2024
Sahlgrenska University Hospital
2018-2024
University of Gothenburg
2024
Karolinska University Hospital
2017-2022
Uppsala University
2016-2018
Lund University
2017-2018
Clinical Research Institute
2016-2018
Duke University
2016-2018
Skåne University Hospital
2018
Impact of changes treatments on outcomes in ST-elevation myocardial infarction (STEMI) patients real-life health care has not been documented. All STEMI cases (n = 105.674) registered the nation-wide SWEDEHEART registry between 1995 and 2014 were included followed for fatal non-fatal up to 20 years. Most treatment occurred from 1994 2008. Evidence-based increased: reperfusion 66.2 81.7%; primary percutaneous coronary intervention: 4.5 78.0%; dual antiplatelet therapy 0 89.6%; statin: 14.1...
Background— For the large and growing population of elderly patients with cardiovascular disease, it is important to identify clinically relevant measures biological age their contribution risk. Frailty an emerging concept in medicine denoting increased vulnerability decreased physiological reserves. We analyzed manner which variable frailty predicts short-term outcomes for non–ST-segment elevation myocardial infarction patients. Methods Results— Patients aged ≥75 years, diagnosed were...
The clinical effect of routine oxygen therapy in patients with suspected acute myocardial infarction who do not have hypoxemia at baseline is uncertain.In this registry-based randomized trial, we used nationwide Swedish registries for patient enrollment and data collection. Patients an saturation 90% or higher were randomly assigned to receive either supplemental (6 liters per minute 6 12 hours, delivered through open face mask) ambient air.A total 6629 enrolled. median duration was 11.6 the...
Early detection of coronary atherosclerosis using computed tomography angiography (CCTA), in addition to artery calcification (CAC) scoring, may help inform prevention strategies. We used CCTA determine the prevalence, severity, and characteristics its association with CAC scores a general population. recruited 30 154 randomly invited individuals age 50 64 years SCAPIS (the Swedish Cardiopulmonary Bioimage Study). The study includes without known heart disease (ie, no previous myocardial...
This study assessed sex differences in treatments, all-cause mortality, relative survival, and excess mortality following acute myocardial infarction.A population-based cohort of all hospitals providing infarction care Sweden (SWEDEHEART [Swedish Web System for Enhancement Development Evidence-Based Care Heart Disease Evaluated According to Recommended Therapies]) from 2003 2013 was included the analysis. Excess rate ratios (EMRRs), adjusted clinical characteristics guideline-indicated...
Patients with myocardial infarction (MI) seldom reach recommended targets for secondary prevention. This study evaluated a smartphone application ("app") aimed at improving treatment adherence and cardiovascular lifestyle in MI patients.Multicenter, randomized trial.A total of 174 ticagrelor-treated patients were to either an interactive patient support tool (active group) or simplified (control addition usual post-MI care. Primary end point was composite nonadherence score measuring...
Most trials that have shown a benefit of beta-blocker treatment after myocardial infarction included patients with large infarctions and were conducted in an era before modern biomarker-based diagnosis percutaneous coronary intervention, antithrombotic agents, high-intensity statins, renin-angiotensin-aldosterone system antagonists.
We assessed the changes in short- and long-term outcomes their relation to implementation of new evidence-based treatments all patients with non-ST-elevation myocardial infarction (NSTEMI) Sweden over 20 years. Cases NSTEMI (n = 205 693) between 1995 2014 were included from nationwide Swedish Web-System for Enhancement Development Evidence-Based Care Heart Disease Evaluated According Recommended Therapies (SWEDEHEART) registry. During years in-hospital invasive procedures increased 1.9%...
Surgical risk scores do not include frailty assessments (eg, gait speed), which are of particular importance for patients with severe aortic stenosis considering transcatheter valve replacement.We assessed the association 5-m speed outcomes in a cohort 8039 who underwent replacement (November 2011-June 2014) and were included Society Thoracic Surgeons/American College Cardiology Transcatheter Valve Therapy Registry. We evaluated between continuous categorical 30-day all-cause mortality...
Background: The comparative efficacy and safety of ticagrelor versus clopidogrel in older patients with myocardial infarction (MI) has received limited study. Methods: We performed an observational analysis all ≥80 years (n=14 005) who were discharged alive aspirin combined either (60.2%) or (39.8%) after a MI between 2010 2017 registered the national registry SWEDEHEART (Swedish Web-System for Enhancement Development Evidence-Based Care Heart Disease Evaluated According to Recommended...
Beta-blockers (BB) are an established treatment following myocardial infarction (MI). However, there is uncertainty as to whether BB beyond the first year of MI have a role in patients without heart failure or left ventricular systolic dysfunction (LVSD).
To study gender differences in management and outcome patients with non-ST-elevation acute coronary syndrome.Cohort of 53 781 consecutive (37% women) from the Register Information Knowledge about Swedish Heart Intensive care Admissions (RIKS-HIA), a diagnosis either unstable angina pectoris or myocardial infarction. All were admitted to intensive units Sweden, between 1998 2002, followed for 1 year.Treatment intensity in-hospital, 30-day 1-year mortality.Women older (73 vs 69 years, p<0.001)...
In ST elevation myocardial infarction women received less evidence-based medicine and had worse outcome during the fibrinolytic era. With shift to primary percutaneous coronary intervention (pPCI) as preferred reperfusion strategy, authors aimed investigate whether these gender differences has diminished.Cohort study including consecutive patients registered 1998-2000 (n=15 697) 2004-2006 (n=14 380) in Register of Information Knowledge about Swedish Heart Intensive care Admissions.1. Use...
For the large population of elderly patients with cardiovascular disease, it is crucial to identify clinically relevant measures biological age and their contribution risk. Frailty denoting decreased physiological reserves increased vulnerability. We analysed manner in which variable frailty associated 1-year outcomes for non-ST-segment elevation myocardial infarction (NSTEMI) patients. Patients aged 75 years or older, diagnosed NSTEMI were included at three centres, clinical data including...
<h3>Importance</h3> Whether certain weather conditions modulate the onset of myocardial infarction (MI) is great interest to clinicians because it could be used prevent MIs as well guide allocation health care resources. <h3>Objective</h3> To determine if associated with day-to-day incidence MI. <h3>Design, Setting, and Participants</h3> In this prospective, population-based nationwide setting, daily data from Swedish Meteorological Hydrological Institute were extracted for all reported...
To describe the time trends of in-hospital and out-of-hospital bleeding parallel to development new treatments ischaemic outcomes over last 20 years in a nationwide myocardial infarction (MI) population.Patients with acute MI (n = 371 431) enrolled SWEDEHEART registry from 1995 until May 2018 were selected evaluated for events at 1 year. In-hospital increased 0.5% peak 2% 2005/2006 thereafter slightly decreased plateau around 1.3% by end study period. Out-of-hospital stepwise fashion 2.5%...
Abstract Objectives To evaluate an artificial intelligence (AI)–based, automatic coronary artery calcium (CAC) scoring software, using a semi-automatic software as reference. Methods This observational study included 315 consecutive, non-contrast-enhanced computed tomography (CSCT) scans. A and obtained the Agatston score (AS), volume (VS), mass (MS), number of calcified lesions. Semi-automatic analysis time were registered, including manual double-check results. Statistical analyses...
Most reports on the declining incidence of myocardial infarction (MI) during COVID-19 have either been anecdotal, survey results or geographically limited to areas with lockdowns. We examined MI pandemic in Sweden, which has remained an open society a different public health approach fighting COVID-19.We assessed rate (IR) as well ratios (IRRs) all referred for coronary angiography Sweden using nationwide Swedish Coronary Angiography and Angioplasty Registry (SCAAR), (1 March 2020-7 May...
Background A significant proportion of patients with ST-segment-elevation myocardial infarction (MI) have no standard modifiable cardiovascular risk factors (SMuRFs) and unexpected worse 30-day outcomes compared those SMuRFs. The aim this article is to examine non-ST-segment-elevation MI in the absence Methods Results Presenting features, management, without SmuRFs (hypertension, diabetes, hypercholesterolemia, smoking) were Swedish registry SWEDEHEART (Swedish Web-System for Enhancement...